Macromolecular Research

The Polymer Society of Korea (한국고분자학회)
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Facile Synthesis of Dendritic-Linear-Dendritic Materials by Click Chemistry

  • Lee, Jae-Wook (Department of Chemistry and Department of Medical Bioscience, Dong-A University) ;
  • Han, Seung-Choul (Department of Chemistry and Department of Medical Bioscience, Dong-A University) ;
  • Kim, Byoung-Ki (Department of Chemistry and Department of Medical Bioscience, Dong-A University) ;
  • Lee, Un-Yup (Department of Chemistry and Department of Medical Bioscience, Dong-A University) ;
  • Sung, Sae-Reum (Department of Chemistry and Department of Medical Bioscience, Dong-A University) ;
  • Kang, Hwa-Shin (Department of Chemistry and Department of Medical Bioscience, Dong-A University) ;
  • Kim, Ji-Hyeon (Department of Chemical and Bio Engineering, Kyungwon University) ;
  • Jin, Sung-Ho (Department of Chemistry Education & Center for Plastic Information System, Pusan National University)
  • Published : 2009.07.25
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Abstract

General, fast, and efficient stitching methods are presented for the synthesis of Fr$\acute{e}$chet-type dendrimers with linear units at a core, as a preliminary investigation for the synthesis of dendritic-linear-dendritic materials. The synthetic strategy involved an inexpensive, 1,3-dipolar, cycloaddition reaction between an alkyne and an azide in the presence of the Cu(I) species, which is known as the best example of click chemistry. The linear core building blocks, 1,7-octadiyne and 1,6-diazidohexane, were chosen to serve as the alkyne and azide functionalities for dendrimer growth via click reactions with the azide and alkyne-dendrons, respectively. These two building blocks were employed together with the azide- and alkyne-functionalized Fr$\acute{e}$chet-type dendrons in a convergent strategy to synthesize two kinds of Fr$\acute{e}$chet-type dendrimers with different linear core units. This comparative efficiency of the click methodology supports the fast and efficient synthesis of dendritic-linear-dendritic materials with the tailor made core unit.

Keywords

References

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