Journal of Korean Academy of Nursing (대한간호학회지)

Korean Society of Nursing Science (한국간호과학회)
권호 표지
DOI QR코드

DOI QR Code

Transition of Symptoms and Quality of Life in Cancer Patients on Chemotherapy

항암화학요법 시행 초기 암환자의 증상 및 삶의 질 변화 양상

  • Kim, Min-Young (Jeju Regional Cancer Center, Jeju National University Hospital)
  • 김민영 (제주대학교병원 제주지역암센터)
  • Published : 2009.06.26
Download PDF
⟨ Previous Next ⟩

Abstract

Purpose: The purpose of this study was to assess changes in pain, fatigue, anorexia, anxiety and quality of life(QOL) in patients with cancer who were on chemotherapy. Methods: Symptoms and QOL were examined both before chemotherapy and after 2 cycles of chemotherapy. The participants were 76 cancer patients receiving chemotherapy in one of 7 hospitals. Results: The patients experienced a mean of 2.22-2.23 symptoms out of 4 symptoms. Patients who were female, or suffered from breast or colorectal cancer experienced more symptoms. Fatigue at present, and most severe fatigue and anorexia in the previous 3 weeks increased significantly. Anxiety and QOL decreased significantly after 2 cycles of chemotherapy. Number of symptoms, anorexia at present, most severe anorexia in past 3 weeks, and anxiety had negative correlations. QOL before chemotherapy showed a positive correlation with QOL after 2 cycles of chemotherapy. In a regression analysis, anxiety, QOL at baseline, income, and the most severe pain in the past 3 weeks were significant predictors of QOL. Conclusion: Physical and psychological factors were significant predictors of both QOL and each subscale, and these factors correlated with each other. These results demonstrate the needs for early assessment and intervention from the start of chemotherapy to decrease symptoms and improve QOL.

Keywords

References

  1. Berger, A. M., & Higginbotham, P. (2000). Correlates of fatigue during and following adjuvant breast cancer chemotherapy: A pilot study. Oncology Nursing Forum, 27, 1443-1448
  2. Byar, K. L., Berger, A. M., Bakken, S. L., & Cetak, M. A. (2006). Impact of adjuvant breast cancer chemotherapy on fatigue, other symptoms, and quality of life. Oncology Nursing Forum, 33, E18-E26 https://doi.org/10.1188/06.ONF.E18-E26
  3. Choi, S. E., Park, H. R., & Ban, J. Y. (2006). Anxiety in patient undergone hematopoietic stem cell transplantation. Journal of Korean Oncology Nursing, 6, 37-46
  4. Chung, B. Y., Yu, X., & Lee, E. H. (2006). Symptom experience, mood disturbance & social support in breast cancer patients undergoing radiotherapy. Journal of Korean Oncology Nursing, 6, 172-180
  5. Chung, C. W., Kim, M. J., Rhee, M. H., & Do, H. G. (2005). Functional status and psychosocial adjustment in gynecologic cancer patients receiving chemotherapy. Korean Journal of Women Health Nursing, 11, 58-66
  6. Curt, G. A., Breitbart, W., Cella, D., Groopman, J. E., Horning, S. J., Itri, L. M., et al. (2005). Impact of cancer-related fatigue on the lives of patients: New findings from the fatigue coalition. Oncologist, 5, 353-360 https://doi.org/10.1634/theoncologist.5-5-353
  7. Dodd, M. J., Miaskowski, C., & Paul, S. M. (2001). Symptom clusters and these effect on the functional status of patients with cancer. Oncology Nursing Forum, 28, 465-470
  8. Doran, D. M., Harrison, M. B., Laschinger, H. S., Hirdes, J. P., Rukholm, E., Sidani, S., et al. (2006). Nursing-sensitive outcomes data collection in acute care and long-term-care settings. Nursing Research, 55, S75-S81 https://doi.org/10.1097/00006199-200603001-00012
  9. Fox, S. W., & Lyon, D. E. (2006). Symptom clusters and quality of life in survivors of lung cancer. Oncology Nursing Forum, 33, 931-936 https://doi.org/10.1188/06.ONF.931-936
  10. Gong, S. H., Lee, S. H., Jung, J. H., Kim, J. Y., Lee, S. Y., & Kim, S. A. (2004). The effect of cancer pain management education on the concerns and hesitancy of pain management in out-patient of terminal gastric cancer. Korean Clinical Nursing Research, 10, 56-69
  11. Harteveld, J. T., Mistiaen, P. J., & Dukkers van Emden, D. M. (1997). Home visits by community nurses for cancer patients after discharge from hospital: An evaluation study of the continuity visit. Cancer Nursing, 20, 105-114 https://doi.org/10.1097/00002820-199704000-00005
  12. Hur, H. K., Lee, E. H., Lee, W. H., So, H. S., Chung, B. Y., & Kang, E. S. (2002). Symptom occurrence related to disease characteristics of adult patients with cancer. Journal of Korean Academy of Adult Nursing, 14, 411-417
  13. Itano, J. K., & Taoka, K. N. (1998). Core Curriculum for oncology nursing (3rd ed.). Philadelphia, PA: Oncology Nursing Society
  14. Kim, H. S., Lee, S. W., Yun, Y. H., Yu, S. J., & Heo, D. S. (2001). Gender differences in pain in cancer patients. Journal of Korean Hospice and Palliative care, 4, 14-25
  15. Kim, J. Y., & Shin, D. K. (1978). A study based on the standardization of the STAI for Korea. The New Medical Journal, 21(11), 69-75
  16. Kim, M. Y. (2008). Nursing outcomes in cancer patients cared by oncology advanced practice nurses during chemotherapy. Unpublished doctoral dissertation, Seoul National University, Seoul
  17. Kim, Y. J., Cho, I. S., & So, H. S. (2004). Changes on index of nausea, vomiting, and retching in hospitalized cancer patients undergoing chemotherapy. Journal of Korean Academy of Nursing, 34, 1326-1333
  18. Korean Central Cancer Registry (KCCR) (2003). 2002 annual report of the Korean Central Cancer Registry. Seoul: Ministry of Health and Welfare Affairs
  19. Korean National Statistical Office (KNSO). (2006). Annual report of the cause of death in Korea. Seoul: Author
  20. Korean Society for Hospice and Palliative Care (KSHPC) & Korean Cancer Study Group (KCSG) (2002). Cancer pain guideline. Seoul: Koonja
  21. Lee, E. O., Yi, M. S., Heo, D. S., Lee, K. S., & Eom, A. Y. (2001). Trajectories and related factors of fatigue in patients undergoing chemotherapy for lung cancer. Journal of Korean Oncology Nursing, 1, 54-64
  22. Lee, J. E. (2005). Symptom experiences according to chemotherapy cycle in patients with breast cancer. Unpublished master's thesis, Yonsei University, Seoul
  23. Oermann, M. H., & Templin, T. (2000). Important attributes of quality health care: Consumer perspectives. Journal of Nursing Scholarship, 2, 167-172 https://doi.org/10.1111/j.1547-5069.2000.00167.x
  24. Sarna, L., Cooley, M. E., Brown, J. K., Williams, R. D., Chernecky, C., Padilla G., et al. (2006). Quality of life and health status of dyads of women with lung cancer and family members. Oncology Nursing Forum, 33, 1109-1116 https://doi.org/10.1188/06.ONF.1109-1116
  25. Sohn, S. K., Kim, K. H., & Kim, S. H. (2007). Relationship between fatigue and functional status in patients with cancer. Journal of Korean Oncology Nursing, 7, 3-13
  26. Son, H. K., Kim, S. H., & Sohn, S. K. (2007). Relationship between fatigue and depression in patients with hemato-malignancy receiving chemotherapy. Journal of Korean Oncology Nursing, 7, 14-25
  27. Spielberger, C. D. (1972). Anxiety current trends in theory and research, 1. New York, NY: Academic Press
  28. Suh, Y. O. (2007). Predictors of quality of life in women with breast cancer. Journal of Korean Academy of Nursing, 37, 459-466
  29. Weaver C., Schiech, L., Held-Warmkessel, J., Kedziera, P., Haney, E., Dilullo, G., et al. (2006). Risk for unplanned hospital readmission of patients with cancer: Results of a retrospective medical record review. Oncology Nursing Forum, 33(3), E44-E52 https://doi.org/10.1188/06.ONF.E44-E52
  30. Yabro, C. H., Frogge, M. H., Goodman, M., & Groenwald, S. L. (2000). Cancer nursing principles and practice (5th ed.). Sudbury, MA: Jones and Bartlett Publishers
  31. Yang, M. J., Jeon, Y. W., Han, S. I., Han, C. W., & Eom, H. S. (2000). Depression and pain in patients with cancer-A preliminary study-. Journal of Korean Neuropsychiatric Association, 39, 1122-1131
  32. Yang, Y. H. (2003). Trajectory of fatigue, quality of life and physical symptoms in cancer patients receiving radiotherapy. Journal of Korean Academy of Nursing, 33, 562-569

Cited by

  1. 항암제 임상시험에 참여 중인 암 환자의 불안, 우울과 불확실성 vol.25, pp.1, 2013, https://doi.org/10.7475/kjan.2013.25.1.53
  2. 직장 남성의 스트레스 및 정서 상태에 따른 금연프로그램의 효과 분석 vol.14, pp.12, 2013, https://doi.org/10.5762/kais.2013.14.12.6364
  3. Changes of Symptom Distress and Quality of Life in Breast Cancer Patients Receiving Adjuvant Therapy vol.15, pp.2, 2009, https://doi.org/10.5388/aon.2015.15.2.67
  4. 항암화학요법을 받고 있는 한국 대장암 환자의 삶의 질 영향 요인 vol.45, pp.4, 2009, https://doi.org/10.4040/jkan.2015.45.4.604
  5. 갑상선암 수술환자의 삶의 질에 영향을 미치는 요인 vol.16, pp.8, 2009, https://doi.org/10.5762/kais.2015.16.8.5442
  6. 항문보존술을 받은 직장암 환자의 배변기능, 불안 및 우울이 삶의 질에 미치는 영향 vol.45, pp.5, 2009, https://doi.org/10.4040/jkan.2015.45.5.733
  7. Quality of life changes during adjuvant chemotherapy in patients with colon cancer vol.12, pp.1, 2009, https://doi.org/10.14216/kjco.16010
  8. A prospective exploration of symptom burden clusters in women with breast cancer during chemotherapy treatment vol.25, pp.5, 2009, https://doi.org/10.1007/s00520-016-3527-1
  9. 대장암·위암 환자의 항암화학요법 시기에 따른 암 증상, 우울 및 삶의 질의 변화: 전향적 종단 연구 vol.29, pp.3, 2009, https://doi.org/10.7475/kjan.2017.29.3.313
  10. The Effect of Visual Information Blocking Nursing Intervention on Stress and Anxiety during Chemoport Insertion in Adult Cancer Patients of Operation Rooms vol.30, pp.2, 2009, https://doi.org/10.7475/kjan.2018.30.2.194
  11. 항암화학요법 치료 중인 노인 암환자의 자가 건강관리 도구 개발: 건강관리 일기장의 효과성 검증 vol.35, pp.2, 2009, https://doi.org/10.14367/kjhep.2018.35.2.73
  12. 오장변증설문지 예측 타당도 연구 vol.32, pp.3, 2018, https://doi.org/10.15188/kjopp.2018.06.32.3.165
  13. A Longitudinal Path Analysis of Symptom, Fatigue and Quality of life in Patients with Colorectal Cancer during Chemotherapy vol.43, pp.3, 2018, https://doi.org/10.21032/jhis.2018.43.3.200
  14. Factors Affecting Sleep Disturbances in Hospitalized Patients with Colorectal Cancer undergoing Chemotherapy: A Retrospective Study vol.31, pp.1, 2009, https://doi.org/10.7475/kjan.2019.31.1.100
  15. 재가암환자를 위한 융합적 통합지지 프로그램의 적용 효과 vol.9, pp.2, 2009, https://doi.org/10.22156/cs4smb.2019.9.2.065
  16. Factors associated with the satisfaction of smoking cessation programs in clinics among Korean military personnel: An application of Transtheoretical model vol.36, pp.5, 2009, https://doi.org/10.14367/kjhep.2019.36.5.1
  17. Factors Related to Utilization of Smoking Cessation Support Service among Attempters for Quitting Smoking vol.45, pp.4, 2009, https://doi.org/10.21032/jhis.2020.45.4.349
  18. The Effects of Foot Reflexology on the Physical Symptoms of Cancer Patients vol.30, pp.1, 2021, https://doi.org/10.15857/ksep.2021.30.1.8
  19. 300인 미만 사업장근로자의 6개월 이내 재흡연 관련요인 vol.32, pp.1, 2009, https://doi.org/10.12799/jkachn.2021.32.1.107
  20. The “Ick” Factor: An Unrecognized Affective Predictor of Physical Symptoms During Chemotherapy vol.55, pp.4, 2009, https://doi.org/10.1093/abm/kaaa055
  21. 한방 암 치료에 대한 최근 10년간 임상연구 고찰: 국내 데이터베이스를 중심으로 vol.31, pp.4, 2009, https://doi.org/10.18325/jkmr.2021.31.4.75