Journal of Biomedical Engineering Research (대한의용생체공학회:의공학회지)

The Korean Society of Medical and Biological Engineering (대한의용생체공학회)
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Development and Evaluation of Multi-Wavelength Excitation light Source for Fluorescence Imaging to Diagnose Malignancies

악성종양의 형광영상 진단을 위한 다파장 여기광원장치의 개발과 평가

  • Lim, Hyun-Soo (Department of Biomedical Engineering, College of Medicine, Chungnam National University)
  • 임현수 (충남대학교 의과대학 의공학교실)
  • Published : 2009.04.30
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Abstract

This study aims at designing and evaluating light source devices that can stably generate light with various wavelengths in order to make possible PDD using a photosensitizer and diagnosis using auto-fluorescence. The light source was a Xenon lamp and filter wheel, composed of an optical output control through Iris and filters with several wavelength bands. It also makes the inducement of auto-fluorescence possible because it is designed to generate a wavelength band of 380-420nm, 430-480nm, and 480-560nm. The transmission part of the light source was developed to enhance the efficiency of light transmission. To evaluate this light source, the characteristics of light output and wavelength band were verified. To validate the capability of this device as PDD, the detection of auto-fluorescence using mouse models was performed.

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References

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