International Journal of Industrial Entomology and Biomaterials

Korean Society of Sericultural Science (한국잠사학회)
권호 표지

Chemical Composition of Main Cordyceps species in Korea

  • Hong, In-Pyo (National Academy of Agricultural Science, R.D.A.) ;
  • Nam, Sung-Hee (National Academy of Agricultural Science, R.D.A.) ;
  • Sung, Gyoo-Byung (National Academy of Agricultural Science, R.D.A.) ;
  • Lee, Kwang-Gil (National Academy of Agricultural Science, R.D.A.) ;
  • Cho, Soo-Muk (National Academy of Agricultural Science, R.D.A.) ;
  • Seok, Soon-Ja (National Academy of Agricultural Science, R.D.A.) ;
  • Hur, Hyeon (Department of Applied Biology, Dongguk University) ;
  • Lee, Min-Woong (Department of Applied Biology, Dongguk University) ;
  • Guo, Shun-Xing (Institute of Medicinal Plant, Chinese Academy of Medical Sciences)
  • Published : 2009.03.31
Download PDF
⟨ Previous Next ⟩

Abstract

The caterpillar-shaped Chinese medicinal mushroom (DongChongXiaCao) looks like a worm in the winter and like a grass in the summer. The fruiting body has been regarded as popular folk or effective medicines used to treat human diseases such as asthma, bronchial and lung inflammation, and kidney disease. The fruiting bodies of Cordyceps militaris, C. pruinosa and Paecilomyces tenuipes that formed on the living silkworm (Bombyx mori) host were used in this examination. This study was carried out to investigate the soluble sugar, amino acid and fatty acid profiles in the fruiting-bodies. Soluble sugars such as glycerol, glucose, mannitol and sucrose were mainly found in the fruiting bodies of C. militaris, C. pruinosa and P. tenuipes. Total soluble sugar content was 29.23 mg/g in C. militaris, 8.61 mg/g in C. pruinosa and 24.00 mg/g 1in P. tenuipes on dry weight basis. Total free amino acid content was 14.09 mg/g 1in C. militaris, 34.60 mg/g in C. pruinosa and 17.09 mg/g in P. tenuipes. The content of oleic acid in fatty acids was above high more than 30% regardless of species.

Keywords

References

  1. Ban KW, Park DK, Shim JO, Lee YS, Park CH, Lee JY, Lee TS, Lee SS, Lee MW (1998) Cultural characteristics for inducing fruiting-body of Isaria japonica. Korean J Mycology 26(3), 380-386
  2. Bok JW, Lermer L, Chilton J, Klingeman HG, Towers GH (1999) Antitumor sterols from the mycelia of Cordyceps sinensis. Phytochemistry 51(7), 891-898 https://doi.org/10.1016/S0031-9422(99)00128-4
  3. Chang HL, Chao GR, Chen CC. Mau JL (2001) Non-volatile taste components of Agaricus blazei, Antrodia camphorata and Cordyceps militaris mycelia. Food Chemistry 74, 203-207 https://doi.org/10.1016/S0308-8146(01)00127-3
  4. Chen, HK (1986) Studies on the characteristics of taste-active components in mushroom concentrate and its powderization. Master's Thesis, National Chung-Hsing University, Taichung, Taiwan
  5. Chiou WF, Chang PC, Chou CJ, Chen CF (2000) Protein constituent contributes to the hypotensive and vasorelaxant activities of Cordyceps sinensis. Life Sci 66(14), 1369-1376 https://doi.org/10.1016/S0024-3205(00)00445-8
  6. Furuya T, Hirotani M, Matsuzawa M (1983) N6-(2-hydroxyethyl) adenosine, a biologically active compound from cultured mycelia of Cordyceps and Isaria species. Phytochemistry 22, 2509-2512 https://doi.org/10.1016/0031-9422(83)80150-2
  7. Gai CZ, Jin SJ, Wang B, Li YQ. Li CX (2004) The efficacy of Cordyceps militaris capsules in treatment of chronic bronchitis in comparison with Jinshuibao capsules. Chinese Journal of New Drugs 13, 169-171
  8. Huang BM, Hsu CC, Tsai SJ, Sheu CC, Leu SF (2001) Effect of Cordyceps sinensis on testosterone production in normal mouse Leydig cells. Life Sci 69, 2593-2602 https://doi.org/10.1016/S0024-3205(01)01339-X
  9. Huang BM, Stocco DM, Norman RL. (1997) The cellular mechanism of corticotropin-releasing hormone (CRH) stimulated steroidogenesis in mouse Leydig cells are similar to those for LH. J Androl 18(5), 528-534
  10. Kim KM, Kwon YG, Chung HT, Yun YG, Pae HO, Han JA, Ha KS, Kim TW and Kim YM (2003) Methanol extract of Cordyceps pruinosa inhibits in vitro and in nivo inflammatory mediators by suppressing NF-\textbullet\acute{a}B activation. Toxicology and applied pharmacology 190, 1-8 https://doi.org/10.1016/S0041-008X(03)00152-2
  11. Kobayashi Y (1982) Key to the taxa of the genera Cordyceps and Torrubiella. Trans. Mycol. Soc. Jpn. 23(3), 29-364
  12. Kuo YC, Lin CY, .Tsai WJ, Wu CL, Chen CF, Shiao MS (1994) Growth inhibitors against tumor cells in Cordyceps sinensis other than cordycepin and polysaccharides. Cancer Invest 12(6), 611-615 https://doi.org/10.3109/07357909409023046
  13. Kuo YC, Tsai WJ, Shiao MS, Chen CF, Lin CY (1996) Cordyceps sinensis as an immunomodulatory agent. Am J Chin Med 24(2), 111-125 https://doi.org/10.1142/S0192415X96000165
  14. Li QS, Zeng W, Yi DH, Huang TF (1998) Studies on the alternation of generations in Cordyceps sinensis. ChungKuoYaoTsaChil 23(4), 210-212
  15. Litchfield JH (1967) Morel mushroom mycelium as a food flavoring material. Biotechnology Bioengineering 9, 289-304 https://doi.org/10.1002/bit.260090303
  16. Manabe N, Sugimoto M, Azuma Y, Taketomo N, Yamashita A, Tsuboi H, Tsunoo A, Kinjo N, Nian-Lai H, Miyamoto H (1996) Effect of the mycelial extract of cultured Cordyceps sinensis on in vivo hepatic energy metabolism in the mouse. Jpn J Pharmacol 70(1), 85-88 https://doi.org/10.1254/jjp.70.85
  17. Ooi VEC, Liu F (1999) A review of pharmacological activity of mushroom polysaccharides. International Journal of Medicinal Mushrooms 1(3), 195-206
  18. Shim JS, Min EG, Chang HR, Lee CY, Kim SS, and Han YH (2000) Cytoctxicity against human cancer cell lines by Paecilomyces tenuipes DGUM 32001. Kor. J Microbial 36, 312-315
  19. Spatafora JW, Blackwell M (1993) Molecular systematics of unitunicate perithecia ascomycetes; the Clavicipitales-Hypocreales connection. Mycologia 85, 912-922 https://doi.org/10.2307/3760674
  20. Wang SM, Lee LJ, Lin WW, Chang CM (1998) Effect of a water-soluble extract of Cordyceps sinensis on steroidogenesis and capsular morphology of lipid droplet in cultured rat adrenocortical cell. J Cell Biochem. 69(4), 483-489 https://doi.org/10.1002/(SICI)1097-4644(19980615)69:4<483::AID-JCB9>3.0.CO;2-J
  21. Wu CS, Leu SF, Yang HY, Huang BM. (2001) Melatonin inhibits the expression of steroidogenic acute regulatory protein and steroidogenesis in MA-10 cells. J Androl 22(5), 245-254
  22. Zhu JS, Halpern GM, Jones K. (1998a) The Scientific rediscovery of an ancient Chinese herbal medicine: Cordyceps sinensis: part Ⅱ . J Altern Complement Med 4(3), 289-303 https://doi.org/10.1089/acm.1998.4.3-289
  23. Zhu JS, Halpern GM, Jones K. (1998b) The Scientific rediscovery of a precious ancient Chinese herbal regimen: Cordyceps sinensis: part Ⅱ. J Altern Complement Med 4(4), 429-457 https://doi.org/10.1089/acm.1998.4.429