A Case of Patella Metastasis of Papillary Thyroid Carcinoma

갑상선 유두암의 슬개골 전이

  • Han, Eun-Ji (Department of Radiology, College of Medicine, The Catholic University of Korea) ;
  • Choi, Woo-Hee (Department of Radiology, College of Medicine, The Catholic University of Korea) ;
  • Chung, Yong-An (Department of Radiology, College of Medicine, The Catholic University of Korea) ;
  • Sohn, Hyung-Sun (Department of Radiology, College of Medicine, The Catholic University of Korea) ;
  • Kang, Chang-Suk (Department of Clinical Pathology, College of Medicine, The Catholic University of Korea)
  • 한은지 (가톨릭대학교 의과대학 방사선과학교실) ;
  • 최우희 (가톨릭대학교 의과대학 방사선과학교실) ;
  • 정용안 (가톨릭대학교 의과대학 방사선과학교실) ;
  • 손형선 (가톨릭대학교 의과대학 방사선과학교실) ;
  • 강창석 (가톨릭대학교 의과대학 병리학교실)
  • Published : 2009.02.28

Abstract

A 73-year-old man presented with a chief complaint of progressive left knee pain for two months. He had a history of total thyroidectomy and central lymph node dissection due to papillary thyroid carcinoma three months ago. MRI images revealed a solid mass in the left patella. A solid mass demonstrated low signal on T1 weighed image, and high signal on T2 weighed image. And whole body bone scan showed focal photon defect in same lesion of left patella. The histologic result of left knee lesion was adenocarcinoma, consistent with metastatic papillary thyroid carcinoma. Although patellar metastasis of papillary thyroid carcinoma is very rare, when knee pain and radiologic abnormality are noted, differential diagnosis of metastasis is necessary.

Keywords

References

  1. Schlumberger MJ. Papillary and follicular thyroid carcinoma. N Engl J Med 1998;338:297-306 https://doi.org/10.1056/NEJM199801293380506
  2. Fred A, Miton J. Essentialls of Nuclear Medicine Imaging. 5th ed. Philadelphia. Saunders; 2006. p. 244-92
  3. Lawrence E, Lord ST, Leon Y, McIntyre PJ, Penix J, Grebenev D, et al. Tall cell papillary thyroid carcinoma metastatic to femur: evidence for thyroid hormone synthesis within the femur. Am J Med Sci 2001;322:103-8 https://doi.org/10.1097/00000441-200108000-00008
  4. Pittas AG, Adler M, Fazzari M, Tickoo S, Rosai J, Larson SM, et al. Bone metastases from thyroid carcinoma: clinical characteristics and prognostic variables in one hundred forty-six patients. Thyroid 2000;10:261-8 https://doi.org/10.1089/thy.2000.10.261
  5. Eroglu A, Karaoglanoglu N, Bilen H, Gursan N. Follicular thyroid carcinoma: metastasis to the sternum, 13 years after total thyroidectomy. Int J Clin Pract 2006;60:1506-8 https://doi.org/10.1111/j.1742-1241.2005.00637.x
  6. Do MY, Rhee Y, Kim DJ, Kim CS, Nam KH, Ahn CW, et al. Clinical features of bone metastases resulting from thyroid cancer: a review of 28 patients over a 20-year period. Endocr J 2005;52:701-7 https://doi.org/10.1507/endocrj.52.701
  7. Jemal A, Siegel R, Ward E, Murray T, Xu J, Thun MJ. Cancer statistics, 2007. CA Cancer J Din 2007;57:43-66 https://doi.org/10.3322/canjclin.57.1.43
  8. Kransdorf MJ, Moser RP, Jr., Vinh TN, Aoki J, Callaghan JJ. Primary tumors of the patella. A review of 42 cases. Skeletal Radiol 1989;18:365-71 https://doi.org/10.1007/BF00361426
  9. Fred A, Milton J. Skeletal system. In: Essentials of Nuclear Medicine Imaging: Saunders; 2006. p. 244-292