YAKHAK HOEJI (약학회지)

The Pharmaceutical Society of Korea (대한약학회)
권호 표지

Evaluation for the Purpose and Relevance of Obesity Treatment in Local Clinics

외래 비만 클리닉에서 행해지는 비만 치료의 목적 및 타당성에 관한 평가

  • Yang, Jeong-Hye (College of Pharmacy, CBITRC, Chungbuk National University) ;
  • Lee, Myung-Koo (College of Pharmacy, CBITRC, Chungbuk National University) ;
  • Lim, Sung-Jin (College of Pharmacy, CBITRC, Chungbuk National University) ;
  • Lee, Bo-Reum (College of Pharmacy, CBITRC, Chungbuk National University) ;
  • Kwon, Ik-Hyun (College of Pharmacy, CBITRC, Chungbuk National University) ;
  • Bang, Joon-Seok (College of Pharmacy, CBITRC, Chungbuk National University) ;
  • Lee, Chong-Kil (College of Pharmacy, CBITRC, Chungbuk National University) ;
  • Lim, Sung-Cil (College of Pharmacy, CBITRC, Chungbuk National University)
  • Published : 2009.02.28
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Abstract

Metabolic syndrome is increasing nowadays and one of causes is obesity. Therefore prevention and treatment of obesity is very important to decrease of Metabolic syndrome. However currently many pharmacotherapy for obesity are popular in Korea and it may be dangerous. The aim of this study is to evaluate the purpose and relevance of obese treatment in two areas (capital & local) of Korea and suggest to guide for the right directions of pharmacotherapy in obesity treatment. We selected and surveyed 90 patients (88 females, 2 males, age of $23{\sim}60$) at random who received a prescription after consulting with a doctor at several clinics of Cheongju-area and Seoul-area, from May thru June, 2007. And we evaluated their prescriptions. In results, only 26.7% were obese (13.3%, 2325), most 73.3% patients were normal (65.6%, 18.5$m^2$). The purpose of treatment was for appearance (38.9%), health (41.1%) or both (18.9%, p<0.01). 94% patients had the past history of obese treatment. Prescriptions were consisted of CNS stimulant, anticonvulsants, antidepressant, laxatives, diuretics, or antianxietics. Obese treatment is very important for health to prevent disease such as Metabolic Syndrome. However it should not be abused. In conclusion, some patients of obese treatment is not relevant to obesity and pharmacist role is important to guide them for the right directions in obesity treatment.

Keywords

References

  1. 한국보건사회연구원 : 2005년도 국민건강영양조사-검진, 보건복지부 (2006)
  2. World Health Organization. Obesity : Preventing and Managing the Global Epidemic. Report of a WHO Consultation on Obesity. World Health Organization, Geneva, Switzerland(1998)
  3. Kanazawa, M., Yoshiike, N. and Osaka, T. : Criteria and classification of obesity in Japan and Asia-Oceania. Asia Pac. J. Clin. Nutr. 11, S732 (2002) https://doi.org/10.1046/j.1440-6047.11.s8.19.x
  4. World Health Organization Regional Office for the Western Pacific (WPRO) : the International Association for the Study of Obesity (IASO) and the International Obesity Task Force (IOTF). The Asia-Pacific Perspective: Redefining Obesity and Its Treatment (2000)
  5. Anuurad, E., Shiwaku, K., Nogi, A., Kitajima, K., Enkhmaa, B., Shimono, K. and Yamane, Y. : The new BMI criteria for asians by the regional office for the western pacific region of WHO are suitable for screening of overweight to prevent metabolic syndrome in elder Japanese workers. J. Occup. Health 45(6), 335 (2003) https://doi.org/10.1539/joh.45.335
  6. Lee, S. Y., Park, H. S., Kim, S. M., Kwon, H. S., Kim, D. J., Cho, G. J., Han, J. H., Kim, S. R., Park, C. Y., Oh, S. J., Lee, C. B., Kim, K. S., Oh, S. W., Kim, Y. S., Choi, W. H. and Woo, H. J. : Cut-off points of waist circumference for defining abdominal obesity in the Korean population. 대한비만학회지15(1), 1 (2006)
  7. Must, A., Spadano, J., Coakley, E. H., Field, A. E., Colditz, G. and Deitz, W. H. : The disease burden associated with overweight and obesity. JAMA 282, 1523(1999)
  8. 한국보건사회연구원 : 한국인의 주요 상병 및 건강행태 분석. 2005년 국민건강영양조사 건강부문 심층분석 결과. 보건복지부(2007)
  9. Grundy, S. M., Cleeman, J. I. and Daniels, S. R. : Diagnosis and management of the metabolic syndrome - An american heart association/national heart, lung, and blood institute scientific statement. Circulation 112, 2735 (2005) https://doi.org/10.1161/CIRCULATIONAHA.105.169404
  10. Lee, W. J., Goh, E. H., Kim, M. S., Park, J. Y. and Lee, K. U. : Recent advances in the treatment of obesity. 당뇨병 28(5), 347 (2004)
  11. Bray, G. A. and Greenway, F. L. : A review of current and potential drugs for treatment of obesity. Endocr Rev. 20, 805(1999) https://doi.org/10.1210/er.20.6.805
  12. Park, Y. W. : Sympathomimetic drugs. J. Korean Acad. Fam. Med. 126 (2005)
  13. Kim, Y. S., M.D. Drug treatment of obesity. 대한내분비학회지 16(1), 9 (2001)
  14. Park, H. S. : Pharmacological therapy of obesity. 대한비만학회지 10, 2 (2001)
  15. 대한비만학회 : 비만의 진단과 치료: 아시아, 태평양지역 지침. 도서출판 한의학, 서울 (2000)
  16. Song, Y. M., MD, PhD, Ha MA, MD, PhD, and Sung JH, MD, PhD. : Body mass index and mortality in a middle-aged Korean Women. Annals of Epidemiology 17, 556 (2007) https://doi.org/10.1016/j.annepidem.2007.01.028
  17. Hayashi, R., Iwasaki, M., Otani, T., Wang, N., Miyazaki, H., Yoshiaki, S., Aoki, S., Koyama, H. and Suzuki, S. : Body mass index and mortality in a middle-aged Japanese cohort. Journal of Epidemiology 15(5), 70 (2005) https://doi.org/10.2188/jea.15.70
  18. Munro, J. F., McCuish, A. C. and Wilson, E. M. : Comparison of continuous and intermittent anorectic therapy in obesity. Br. Med. J. 1, 352 (1968) https://doi.org/10.1136/bmj.1.5588.352
  19. Park, Y. W. : Efficacy and safety of phentermine for obese patients: A preliminary open-label study. 대한비만학회지 14, 1 (2005)
  20. Bray, G. A., Hollander, P., Klein, S., Kushner, R., Levy, B., Fitchet, M. and Perry, B. H. : A 6-month randomized, placebocontrolled, dose-ranging trial of topiramate for weight loss in obesity. Obesity 11, 6 (2003)
  21. Halpren, A. and Mancini, M. C. : Treatment of obesity: an update on anti-obesity medications. The international Associations for the Study of Obesity 4, 25 (2003)