Evaluation of the Risk of Metabolic Syndrome for the Young Adults in Korean Students of a University

한국인 대학생군 대상의 청.장년층 대사이상증후군 위험성 평가

  • Published : 2009.02.28

Abstract

Metabolic syndrome, defined as the clustering of several metabolic disorders including obesity (waist circumference ${\geq}90$ if male or ${\geq}80$ if female, cm), dyslipidemia ($TG{\geq}150$ or HDL-C<40 if male or <50 if female, mg/dl), hypertension ($BP{\geq}130/85mmHg$) and hyperglycemia (fasting plasma $glucose{\geq}110mg/dl$), increases the cardiovascular risk of the general population. Recently, risk of this syndrome arises in young adults world widely. Therefore, we randomly selected and evaluated the risk of metabolic syndrome of total 43 people (group I-22, group II-21) for 2 years. Group I was 22 peoples (15 males, 7 females) with age of 22 thru 35 year old (average 28 year old) and group II was 21 people (19 male, 2 female) with age of 22 thur 32 years old (average 24 year old) in Cheongju area from March 1st thru 30th of 2008 in Cheongju area from September 1st thru 30th of 2007 in order to find out how serious this phenomenon is in young adult of Korea. 13.95% (n=7) of total people has a metabolic syndrome by NCEP/ATPIII definition among this group (group I-6, group II-1). Those of 6 have 3 or over risk factor for metabolic syndrome such as obesity, hypertension, fasting blood glucose and hypetriglyceridemia at the same time (group I-5, group II-1). Group I have more risk factor because of more higher age than group II. Therefore we need aggressively to monitor and provide them for early diagnosis, educational programs and assistance for lifestyle changes in order to prevent metabolic syndrome among young adults.

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References

  1. Solymoss, B. C., Bourassa, M. G. and Campcau, L. : Effect of increasing metabolic syndrome score on atherosclertic risk profile and coronary artery disease angiogtaphic severity. Am. J. Cardiol. 93, 159 (2004) https://doi.org/10.1016/j.amjcard.2003.09.032
  2. Isomaa, B., Almgtren, P. and Tuomi, T. : Cardiovascular morbidity and mortality associated with the metabolic syndrome. Diabetes Care. 24, 683 (2001) https://doi.org/10.2337/diacare.24.4.683
  3. Laaksonen, D. E., Lakka, H. M., Niskanen, L. K., Kaplan, G. A., Salonen, J. T. and Lakka, T. A. : Metabolic syndrome and development of diabetes mellitus: application and validation of recently suggested definitions of the metabolic syndrome in a prospective cohort study. Am. J. Epidemiol. 156, 1070 (2002) https://doi.org/10.1093/aje/kwf145
  4. The US National Cholesterol Education Program (NCEP) Expert Panel: Third report of the National Cholesterol Education Program Expert Panel on Detection, Evalution, and Treatment of High Blood Cholesterol in Adults Adult Treatment Panel III (ATPIII) final report. Circulation. 106, 3143 (2002)
  5. Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel). JAMA 285, 2486 (2001)
  6. Kim, H. C., Choi, K. S., Jang, Y. H., Shin, H. W. and Kim, D. J. : Normal serum aminotransferase levels and the metabolic syndrome: Korean National Health and Nutrition Examination Surveys. Yonsei Med. J. 47, 542 (2006) https://doi.org/10.3349/ymj.2006.47.4.542
  7. WHO : Physical status: The use and interpretation of anthropometry. WHO Technical Report Series. Geneva, WHO, p. 854 (1995)
  8. World Health Organization. Geneva, World Health Organization : Diet, nutrition and the prevention of chronic diseases: report of a joint WHO/FAO expert consultation. WHO 916, (2003)
  9. Tapia Ceballos, L., Lopez Siguero, J. P. and Jurado Ortiz, A. : Prevalence of metabolic syndrome and its components in obese children and adolescents. An. Pediatr. (Barc). 67, 352(2007) https://doi.org/10.1016/S1695-4033(07)70653-7
  10. Grandi, A. M., Maresca, A. M., Giudici, E., Laurita, E., Marchesi, C. and Solbiati, F. : Metabolic syndrome and morphofunctional characteristics of the left ventricle in clinically hypertensive nondiabetic subjects. Am. J. Hypertens 19, 199 (2006) https://doi.org/10.1016/j.amjhyper.2005.07.024
  11. Reilly, M. P. and Rader, D. J. : The metabolic syndrome: more than sum of its parts? Circulation. 108, 1546 (2003) https://doi.org/10.1161/01.CIR.0000088846.10655.E0
  12. Scuteri, A., Najjar, S. S., Muller, D. C., Andres, R., Hougaku, H. and Metter, E. J. : Metabolic syndrome amplifies the ageassociated increases in vascular thckness and stiffness. J. Am. Coll. Cardiol. 43, 1388 (2004) https://doi.org/10.1016/j.jacc.2003.10.061
  13. Grassi, G. and Giannattasio, C. : Obesity and vascular stiffness: when body fat has an adverse impact on arterial dynamics. J. Hypertens. 23, 1789 (2005) https://doi.org/10.1097/01.hjh.0000182524.67310.8e
  14. Kosch, M., Barenbrock, M., Kisters, K., Rahn, K. H. and Haysberg, M. : Relationship between muscle sympathetic nerve activity and large artery mechanical vessel wall properties in renal transplant patients. J. Hypertens. 20, 501(2002) https://doi.org/10.1097/00004872-200203000-00026
  15. Westerbacka, J., Seppälä-Lindroos, A. and Yki-Järvinen, H. : Resistance to acute insulin induced decreases in large artery stiffness accompanies the insulin resistance syndrome. J. Clin. Endorcrinol. Metab. 86, 5262 (2001) https://doi.org/10.1210/jc.86.11.5262
  16. Malik, S., Wong, N. D., Franklin, S. S., Kamath, T. V. and L'Italien, G. J. : Impact of the metabolic syndrome on mortality from coronary heart disease, cardiovascular disease, and all causes in United States adults. Circulation. 110, 1245 (2004) https://doi.org/10.1161/01.CIR.0000140677.20606.0E
  17. Kawamoto, R., Tomita, H., Oka, Y. and Ohtsuka, N. : Relationship between serum uric acid concentration, metabolic syndrome and carotid atherosclerosis. Intern. Med. 45, 605(2006) https://doi.org/10.2169/internalmedicine.45.1661