한국어병학회지 (Journal of fish pathology)

  • 제22권2호
  • /
  • Pages.107-113
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  • 2009
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  • 1226-0819(pISSN)
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  • 2233-5412(eISSN)
한국어병학회 (The Korean Society of Fish Pathology)
권호 표지

국내산 메기, Silurus asotus의 상피종

Epithelioma of farmed catfish Silurus asotus in Korea

  • Yu, Jin-Ha (Department of Aquatic Life Medicine, Kunsan National University) ;
  • Park, Sung-Woo (Department of Aquatic Life Medicine, Kunsan National University) ;
  • Kim, Dong-Wan (Dongkyung Microbial Technology)
  • 발행 : 2009.08.01
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초록

지중 양식 중인 메기, Silurus asotus에 Ameiurus nrbulosus 상피종과 유사한 질병이 발생하였다. 상피종은 피부, 지느러미 및 수염에 독립된 형태로 대형의 종괴를 형성하고 있었으며, 조직학적으로는 증생된 상피를 관입된 결합조직에 의해 피포되어 구획되어져 있으며, 증생된 상피 세포는 불규칙한 배열을 하고 있었다. 또한 종양의 내부에는 점액세포와 곤봉세포가 다수 내재되어 있었다. 본 상피종의 발생 원인은 단정할 수는 없지만 상피종을 유발하는 것으로 알려진 바이러스는 검출되지 않았기 때문에 기존에 어류의 종양원으로 보고된 바이러스이외의 종류이던가 아니면 다른 요인이 작용할 것으로 생각되지만 본 연구에서는 원인을 추정할 수 없었다.

Catfish Silurus asotus sampled from a pond farm in Korea, was affected with an epithelial tumor resembling catfish Ameiurus nrbulosus lip and mouth epithelioma. The neoplasm appeared in the form of solitary, multiple, large and fleshy masses upon the skin, fin or barbel. The epithelial tumor proliferation causes papillary folds supported by connective tissue cords. These folds extended above the normal skin surface and into the underlying dermis. In some area, proliferation of mucous cells or club cells were observed. The epithelial cells of the tumor were dispersed with no orderly arrangement. This is the first report on epithelioma of catfish in Korea.

키워드

참고문헌

  1. Andres, K.: A herpesvirus associated with an epizooticepidermal papillomatosis in Europeansmelt (Osmerus eperlanus). In: Ahne, W. &Kurstak, E. (eds.) Viruses of lower vertebrate.Springer, Berlin, pp. 301-306, 1989
  2. Anders, K. and Yoshimizu, M.: Role of viruses inthe induction of skin tumours and tumourlikeproliferations of fish. Dis. Aquat. Org.,19: 215-232, 1994 https://doi.org/10.3354/dao019215
  3. Aso Y., Wani J., Klenner D.A.S. and Yoshimizu M.: Detection and identification of Oncorhynchus masou virus (OMV) disease by polymerase chain reaction (PCR). Bull. Fish. Sci. Hokkaido Univ., 52: 111-116, 2001
  4. Bekesi, L., Horvath, T., Kovacs-Gayer, E. and Csaba,G.: Demonstration of herpesvirus-likeparticles in skin lesions of European eel (Anguillaanguilla). J. Appl. Ichthyol., 2: 190-192, 1986 https://doi.org/10.1111/j.1439-0426.1986.tb00662.x
  5. Blazer, A. S., Fournie, J. W., Wolf, J. C. and Wolfe,M. J.: Manual for the microscopic diagnosis of proliferative liver and skin lesion in the brown bullhead (Ameiurus nebulosus). Pennsylvania Sea Grant. pp 1-34, 2007
  6. Bloch, B., Mellergaard, S. and Nielsen, E.: Adenovirus- like particles associated with epithelial hyperplasias in dab, Limanda limanda (L.). J. Fish. Dis., 9: 281-285, 1986 https://doi.org/10.1111/j.1365-2761.1986.tb01015.x
  7. Carlisle, J. C.: An epidermal papilloma of the Atlanticsalmon Ⅱ: Ultrastructure and etiology. J. Wildlife Dis., 13: 235-239, 1977
  8. David, H. C.: Essential histology. 2nd Ed. pp 142,2001
  9. Kim, Y. G. and Lee, K. K.: Studies on disease ofcatfish (Silurus asotus) in Korea. J. Fish.Pathol., 6: 1-10, 1993
  10. Luck$\acute{e}$, B. and Schlumberger, H.: Transplantable epitheliomasof the lip and mouth of catfish. I.Pathology. Transplantation to anterior chamber of the eye and into the cornea. J. Exp.Med., 74: 397-416, 1941 https://doi.org/10.1084/jem.74.5.397
  11. Oh, M. J., Kitamura, S. I. and Jung, S. J.: Differentiationof lymphocystis disease virus genotypeby multiplex PCR. J. Microbiol., 44: 248-253, 2006
  12. Paperna, I., Vilenkin, M. and Matos, A. P. A.: Iridovirus infections in farm-reared tropical ornamental fish. Dis. Aquat. Org., 48: 17-25, 2001 https://doi.org/10.3354/dao048017
  13. Pinkney, A. E. and Harshbarger, J. C.: Tumorprevalence in brown bullhead (Ameiurusnebulosus) from the south river, Anne ArundelCounty, Maryland. U.S. Fish. Wildfish.Service. pp 1-27, 2005
  14. Romero, C. H., Woodruff, R. A., Bonde, R. K. and Bonilla, A.: Molecular identification of a papillomavirus from cutaneous lesions of captive and free-ranging Florida Manatees. J.Wild. Dis., 41: 437-441, 2005
  15. Sano, T., Morita, N., Shima, N. and Akimoto, M.: A preliminary report on pathogenicity and oncogenicity of cyprinid herpesvirus. Bull.Eur. Ass. Fish Pathol., 10: 11-13, 1990
  16. Schubert, G.: The infective agent in carp pox. Bull.Off. Int. Epiz., 65: 1011-1022, 1966
  17. Sonstegard, R. A.: Environmental carcinogenesisstudies in fishes of the Great Lakes of NorthAmerica. Ann. N.Y. Acad. Sci., 298: 261-269, 1977 https://doi.org/10.1111/j.1749-6632.1977.tb19270.x
  18. Wolf, K.: Fish viruses and fish viral diseases. CornellUniv. Press, Ithaca, pp 476, 1988
  19. Yamamoto, T., MacDonald, R. E., Gillespie, D. C. and Kelly, R. K.: Viruses associated with lymphocystis disease and the dermal sarcoma of walleye (Stizostedion vitreum). J. Fish. Res. Bd. Can., 33: 2408-2419, 1976 https://doi.org/10.1139/f76-287
  20. Yoshimizu, M., Nomura, T., Awakaru, T., Ezura, Y.and Kimura, T.: Prevalence of pathogenicfish viruses in anadromous masu salmon (Oncorhynchus masou) in the northern eastof Japan, 1976-1987. Physiol. Ecol. Jap.Spec., 1: 559-576, 1989