Acknowledgement
Supported by : Ministry of Health and Welfare, Korea Research Foundation, Stem Cell Research Center
References
- Bartek, J., and Lukas, J. (2006). Cell biology. Balancing life-or-death decisions. Science 314, 261-262 https://doi.org/10.1126/science.1133758
- Bartel, D.P. (2004). MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116, 281-297 https://doi.org/10.1016/S0092-8674(04)00045-5
- Bentwich, I., Avniel, A., Karov, Y., Aharonov, R., Gilad, S., Barad, O., Barzilai, A., Einat, P., Einav, U., Meiri, E., et al. (2005). Identification of hundreds of conserved and nonconserved human microRNAs. Nat. Genet. 37, 766-770 https://doi.org/10.1038/ng1590
- Card, D.A., Hebbar, P.B., Li, L., Trotter, K.W., Komatsu, Y., Mishina, Y., and Archer, T.K. (2008). Oct4/Sox2-regulated miR-302 targets cyclin D1 in human embryonic stem cells. Mol. Cell. Biol. 28, 6426-6438 https://doi.org/10.1128/MCB.00359-08
- Carleton, M., Cleary, M.A., and Linsley, P.S. (2007). MicroRNAs and cell cycle regulation. Cell Cycle 6, 2127-2132 https://doi.org/10.4161/cc.6.17.4641
- Cho, W.C. (2007). OncomiRs: the discovery and progress of microRNAs in cancers. Mol. Cancer 6, 60 https://doi.org/10.1186/1476-4598-6-60
- Cimmino, A., Calin, G.A., Fabbri, M., Iorio, M.V., Ferracin, M., Shimizu, M., Wojcik, S.E., Aqeilan, R.I., Zupo, S., Dono, M., et al. (2005). miR-15 and miR-16 induce apoptosis by targeting BCL2. Proc. Natl. Acad. Sci. USA 102, 13944-13949 https://doi.org/10.1073/pnas.0506654102
- Doree, M., and Galas, S. (1994). The cyclin-dependent protein kinases and the control of cell division. FASEB J. 8, 1114-1121 https://doi.org/10.1096/fasebj.8.14.7958616
- Hayashita, Y., Osada, H., Tatematsu, Y., Yamada, H., Yanagisawa, K., Tomida, S., Yatabe, Y., Kawahara, K., Sekido, Y., and Takahashi, T. (2005). A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation. Cancer Res. 65, 9628-9632 https://doi.org/10.1158/0008-5472.CAN-05-2352
- He, L., and Hannon, G.J. (2004). MicroRNAs: small RNAs with a big role in gene regulation. Nat. Rev. Genet. 5, 522-531 https://doi.org/10.1038/nrg1379
- He, L., Thomson, J.M., Hemann, M.T., Hernando-Monge, E., Mu, D., Goodson, S., Powers, S., Cordon-Cardo, C., Lowe, S.W., Hannon, G.J., et al. (2005). A microRNA polycistron as a potential human oncogene. Nature 435, 828-833 https://doi.org/10.1038/nature03552
- Kamikubo, Y., Takaori-Kondo, A., Uchiyama, T., and Hori, T. (2003). Inhibition of cell growth by conditional expression of kpm, a human homologue of Drosophila warts/lats tumor suppressor. J. Biol. Chem. 278, 17609-17614 https://doi.org/10.1074/jbc.M211974200
- Ke, H., Pei, J., Ni, Z., Xia, H., Qi, H., Woods, T., Kelekar, A., and Tao, W. (2004). Putative tumor suppressor Lats2 induces apoptosis through downregulation of Bcl-2 and Bcl-x(L). Exp. Cell Res. 298, 329-338 https://doi.org/10.1016/j.yexcr.2004.04.031
- Kim, K.S., Kim, J.S., Lee, M.R., Jeong, H.S., and Kim, J. (2009). A study of microRNAs in silico and in vivo: emerging regulators of embryonic stem cells. FEBS J. 276, 2410-2149
- Lee, R.C., and Ambros, V. (2001). An extensive class of small RNAs in Caenorhabditis elegans. Science 294, 862-864 https://doi.org/10.1126/science.1065329
- Lee, R.C., Feinbaum, R.L., and Ambros, V. (1993). The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75, 843-854 https://doi.org/10.1016/0092-8674(93)90529-Y
- Lee, N.S., Kim, J.S., Cho, W.J., Lee, M.R., Steiner, R., Gompers, A., Ling, D., Zhang, J., Strom, P., Behlke, M., et al. (2008). miR- 302b maintains 'stemness' of human embryonal carcinoma cells by post-transcriptional regulation of Cyclin D2 expression. Biochem. Biophys. Res. Commun. 377, 434-440 https://doi.org/10.1016/j.bbrc.2008.09.159
- Lee, K.H., Goan, Y.G., Hsiao, M., Lee, C.H., Jian, S.H., Lin, J.T., Chen, Y.L., and Lu, P.J. (2009). MicroRNA-373 (miR-373) posttranscriptionally regulates large tumor suppressor, homolog 2 (LATS2) and stimulates proliferation in human esophageal cancer. Exp. Cell Res. 315, 2529-2538 https://doi.org/10.1016/j.yexcr.2009.06.001
- Leung, W.K., Wu, M.S., Kakugawa, Y., Kim, J.J., Yeoh, K.G., Goh, K.L., Wu, K.C., Wu, D.C., Sollano, J., Kachintorn, U., et al. (2008). Screening for gastric cancer in Asia: current evidence and practice. Lancet Oncol. 9, 279-287 https://doi.org/10.1016/S1470-2045(08)70072-X
- Lewis, B.P., Shih, I.H., Jones-Rhoades, M.W., Bartel, D.P., and Burge, C.B. (2003). Prediction of mammalian microRNA targets. Cell 115, 787-798 https://doi.org/10.1016/S0092-8674(03)01018-3
- Li, Y., Pei, J., Xia, H., Ke, H., Wang, H., and Tao, W. (2003). Lats2, a putative tumor suppressor, inhibits G1/S transition. Oncogene 22, 4398-4405 https://doi.org/10.1038/sj.onc.1206603
- Lu, J., Getz, G., Miska, E.A., Alvarez-Saavedra, E., Lamb, J., Peck, D., Sweet-Cordero, A., Ebert, B.L., Mak, R.H., Ferrando, A.A., et al. (2005). MicroRNA expression profiles classify human cancers. Nature 435, 834-838 https://doi.org/10.1038/nature03702
- Matsui, Y., Nakano, N., Shao, D., Gao, S., Luo, W., Hong, C., Zhai, P., Holle, E., Yu, X., Yabuta, N., et al. (2008). Lats2 is a negative regulator of myocyte size in the heart. Circ. Res. 103, 1309- 1318 https://doi.org/10.1161/CIRCRESAHA.108.180042
- Mertens-Talcott, S.U., Chintharlapalli, S., Li, X., and Safe, S. (2007). The oncogenic microRNA-27a targets genes that regulate specificity protein transcription factors and the G2-M checkpoint in MDA-MB-231 breast cancer cells. Cancer Res. 67, 11001- 11011 https://doi.org/10.1158/0008-5472.CAN-07-2416
- O'Donnell, K.A., Wentzel, E.A., Zeller, K.I., Dang, C.V., and Mendell, J.T. (2005). c-Myc-regulated microRNAs modulate E2F1 expression. Nature 435, 839-843 https://doi.org/10.1038/nature03677
- Saito, Y., Suzuki, H., and Hibi, T. (2009). The role of microRNAs in gastrointestinal cancers. J. Gastroenterol. 44 (Suppl 19), 18-22 https://doi.org/10.1007/s00535-008-2285-3
- Suh, M.R., Lee, Y., Kim, J.Y., Kim, S.K., Moon, S.H., Lee, J.Y., Cha, K.Y., Chung, H.M., Yoon, H.S., Moon, S.Y., et al. (2004). Human embryonic stem cells express a unique set of microRNAs. Dev. Biol. 270, 488-498 https://doi.org/10.1016/j.ydbio.2004.02.019
- Takamizawa, J., Konishi, H., Yanagisawa, K., Tomida, S., Osada, H., Endoh, H., Harano, T., Yatabe, Y., Nagino, M., Nimura, Y., et al. (2004). Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival. Cancer Res. 64, 3753-3756 https://doi.org/10.1158/0008-5472.CAN-04-0637
- Volinia, S., Calin, G.A., Liu, C.G., Ambs, S., Cimmino, A., Petrocca, F., Visone, R., Iorio, M., Roldo, C., Ferracin, M., et al. (2006). A microRNA expression signature of human solid tumors defines cancer gene targets. Proc. Natl. Acad. Sci. USA 103, 2257-2261 https://doi.org/10.1073/pnas.0510565103
- Voorhoeve, P.M., le Sage, C., Schrier, M., Gillis, A.J., Stoop, H., Nagel, R., Liu, Y.P., van Duijse, J., Drost, J., Griekspoor, A., et al. (2006). A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors. Cell 124, 1169-1181 https://doi.org/10.1016/j.cell.2006.02.037
- Wu, W., Sun, M., Zou, G.M., and Chen, J. (2007). MicroRNA and cancer: Current status and prospective. Int. J. Cancer 120, 953- 960 https://doi.org/10.1002/ijc.22454
- Yabuta, N., Fujii, T., Copeland, N.G., Gilbert, D.J., Jenkins, N.A., Nishiguchi, H., Endo, Y., Toji, S., Tanaka, H., Nishimune, Y., et al. (2000). Structure, expression, and chromosome mapping of LATS2, a mammalian homologue of the Drosophila tumor suppressor gene lats/warts. Genomics 63, 263-270 https://doi.org/10.1006/geno.1999.6065
- Zamore, P.D., and Haley, B. (2005). Ribo-gnome: the big world of small RNAs. Science 309, 1519-1524 https://doi.org/10.1126/science.1111444
Cited by
- hNaa10p contributes to tumorigenesis by facilitating DNMT1-mediated tumor suppressor gene silencing vol.120, pp.8, 2010, https://doi.org/10.1172/jci42275
- Targeting YAP and Hippo signaling pathway in liver cancer vol.14, pp.8, 2009, https://doi.org/10.1517/14728222.2010.499361
- The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version vol.24, pp.9, 2009, https://doi.org/10.1101/gad.1909210
- Stability of the LATS2 Tumor Suppressor Gene Is Regulated by Tristetraprolin vol.285, pp.23, 2010, https://doi.org/10.1074/jbc.m109.094235
- MicroRNA expression and its implication for the diagnosis and therapeutic strategies of gastric cancer vol.297, pp.2, 2009, https://doi.org/10.1016/j.canlet.2010.07.018
- Targeting miR-375 in gastric cancer vol.15, pp.8, 2009, https://doi.org/10.1517/14728222.2011.581232
- The Role of microRNAs in Helicobacter pylori Pathogenesis and Gastric Carcinogenesis vol.1, pp.None, 2009, https://doi.org/10.3389/fcimb.2011.00021
- MicroRNAs Regulate Key Effector Pathways of Senescence vol.2011, pp.None, 2011, https://doi.org/10.4061/2011/205378
- miR-Sens-a retroviral dual-luciferase reporter to detect microRNA activity in primary cells vol.18, pp.5, 2009, https://doi.org/10.1261/rna.031831.111
- An update on targeting Hippo-YAP signaling in liver cancer vol.16, pp.3, 2009, https://doi.org/10.1517/14728222.2012.662958
- Titrated extract of Centella asiatica provides a UVB protective effect by altering microRNA expression profiles in human dermal fibroblasts vol.30, pp.5, 2009, https://doi.org/10.3892/ijmm.2012.1117
- Centella asiatica protects against UVB-induced HaCaT keratinocyte damage through microRNA expression changes vol.30, pp.6, 2009, https://doi.org/10.3892/ijmm.2012.1157
- Hippo signaling pathway in mammals:a new therapeutic target for tumors : Hippo signaling pathway in mammals:a new therapeutic target for tumors vol.34, pp.3, 2012, https://doi.org/10.3724/sp.j.1005.2012.00269
- MicroRNAs as Diagnostic Biomarkers in Gastric Cancer vol.13, pp.10, 2009, https://doi.org/10.3390/ijms131012544
- Regulators of mammalian Hippo pathway in cancer vol.1826, pp.2, 2009, https://doi.org/10.1016/j.bbcan.2012.05.006
- Involvement of parental imprinting in the antisense regulation of onco-miR-372-373 vol.4, pp.1, 2013, https://doi.org/10.1038/ncomms3724
- Correlation of microrna-372 upregulation with poor prognosis in human glioma vol.8, pp.1, 2009, https://doi.org/10.1186/1746-1596-8-1
- microRNA-372 maintains oncogene characteristics by targeting TNFAIP1 and affects NFκB signaling in human gastric carcinoma cells vol.42, pp.2, 2013, https://doi.org/10.3892/ijo.2012.1737
- MicroRNA-373 is upregulated and targets TNFAIP1 in human gastric cancer, contributing to tumorigenesis vol.6, pp.5, 2013, https://doi.org/10.3892/ol.2013.1534
- Caudatin induces cell apoptosis in gastric cancer cells through modulation of Wnt/β-catenin signaling vol.30, pp.2, 2009, https://doi.org/10.3892/or.2013.2495
- Pregnancy-associated miRNA-clusters vol.97, pp.1, 2009, https://doi.org/10.1016/j.jri.2012.11.001
- NEDD4 E3 ligase inhibits the activity of the Hippo pathway by targeting LATS1 for degradation vol.12, pp.24, 2009, https://doi.org/10.4161/cc.26672
- Mir-302 cluster exhibits tumor suppressor properties on human unrestricted somatic stem cells vol.35, pp.7, 2009, https://doi.org/10.1007/s13277-014-1844-x
- miR-374b-5p suppresses RECK expression and promotes gastric cancer cell invasion and metastasis vol.20, pp.46, 2014, https://doi.org/10.3748/wjg.v20.i46.17439
- miR-7 inhibits the invasion and metastasis of gastric cancer cells by suppressing epidermal growth factor receptor expression vol.31, pp.4, 2014, https://doi.org/10.3892/or.2014.3052
- miR-338-3p Suppresses Gastric Cancer Progression through a PTEN-AKT Axis by Targeting P-REX2a vol.12, pp.3, 2009, https://doi.org/10.1158/1541-7786.mcr-13-0507
- Targeting the Production of Oncogenic MicroRNAs with Multimodal Synthetic Small Molecules vol.9, pp.3, 2014, https://doi.org/10.1021/cb400668h
- MicroRNA and signaling pathways in gastric cancer vol.21, pp.8, 2009, https://doi.org/10.1038/cgt.2014.37
- miR-372 inhibits p62 in head and neck squamous cell carcinoma in vitro and in vivo vol.6, pp.8, 2015, https://doi.org/10.18632/oncotarget.3340
- MicroRNAs in tumorigenesis, metastasis, diagnosis and prognosis of gastric cancer vol.22, pp.6, 2009, https://doi.org/10.1038/cgt.2015.19
- Upregulation of miR-372 and -373 associates with lymph node metastasis and poor prognosis of oral carcinomas : miR-372 and -373 in OSCC vol.125, pp.11, 2009, https://doi.org/10.1002/lary.25464
- Low mir-372 expression correlates with poor prognosis and tumor metastasis in hepatocellular carcinoma vol.15, pp.None, 2009, https://doi.org/10.1186/s12885-015-1214-0
- Deep-sequencing identification of differentially expressed miRNAs in decidua and villus of recurrent miscarriage patients vol.293, pp.None, 2009, https://doi.org/10.1007/s00404-016-4038-5
- Long Non-Coding RNAs (lncRNAs) of Sea Cucumber: Large-Scale Prediction, Expression Profiling, Non-Coding Network Construction, and lncRNA-microRNA-Gene Interaction Analysis of lncRNAs in Apostichopus vol.18, pp.4, 2016, https://doi.org/10.1007/s10126-016-9711-y
- microRNA-372 Suppresses Migration and Invasion by Targeting p65 in Human Prostate Cancer Cells vol.35, pp.12, 2009, https://doi.org/10.1089/dna.2015.3186
- hsa-miR-376c-3p Regulates Gastric Tumor Growth Both In Vitro and In Vivo vol.2016, pp.None, 2009, https://doi.org/10.1155/2016/9604257
- miR-135b, upregulated in breast cancer, promotes cell growth and disrupts the cell cycle by regulating LATS2 vol.48, pp.5, 2016, https://doi.org/10.3892/ijo.2016.3405
- MicroRNA-524-5p suppresses the growth and invasive abilities of gastric cancer cells vol.11, pp.3, 2016, https://doi.org/10.3892/ol.2016.4143
- Upregulation of miR-34a by diallyl disulfide suppresses invasion and induces apoptosis in SGC-7901 cells through inhibition of the PI3K/Akt signaling pathway vol.11, pp.4, 2009, https://doi.org/10.3892/ol.2016.4266
- MicroRNAs in Pregnancy and Gestational Diabetes Mellitus: Emerging Role in Maternal Metabolic Regulation vol.17, pp.5, 2009, https://doi.org/10.1007/s11892-017-0856-5
- Decreased expression of hsa-miR-372 predicts poor prognosis in patients with gallbladder cancer by affecting chloride intracellular channel 1 vol.16, pp.5, 2017, https://doi.org/10.3892/mmr.2017.7520
- microRNA-372 inhibits proliferation and induces apoptosis in human breast cancer cells by directly targeting E2F1 vol.16, pp.6, 2017, https://doi.org/10.3892/mmr.2017.7591
- Repression of MicroRNA‐372 by Arsenic Sulphide Inhibits Prostate Cancer Cell Proliferation and Migration through Regulation of large tumour suppressor kinase 2 vol.120, pp.3, 2009, https://doi.org/10.1111/bcpt.12687
- Differential MicroRNA Expression Profile of Colon Cancer Stem Cells Derived from Primary Tumor and HT-29 Cell line vol.10, pp.8, 2009, https://doi.org/10.5812/ijcm.8182
- The LATS1 and LATS2 tumor suppressors: beyond the Hippo pathway vol.24, pp.9, 2009, https://doi.org/10.1038/cdd.2017.99
- Downregulation of ULK 1 by micro RNA ‐372 inhibits the survival of human pancreatic adenocarcinoma cells vol.108, pp.9, 2009, https://doi.org/10.1111/cas.13315
- Downregulation of MiR-31 stimulates expression of LATS2 via the hippo pathway and promotes epithelial-mesenchymal transition in esophageal squamous cell carcinoma vol.36, pp.1, 2009, https://doi.org/10.1186/s13046-017-0622-1
- MicroRNA-1225-5p behaves as a tumor suppressor in human glioblastoma via targeting of IRS1 vol.11, pp.None, 2009, https://doi.org/10.2147/ott.s178001
- miR-372 promotes breast cancer cell proliferation by directly targeting LATS2 vol.15, pp.3, 2018, https://doi.org/10.3892/etm.2018.5761
- miRNA-103a-3p Promotes Human Gastric Cancer Cell Proliferation by Targeting and Suppressing ATF7 in vitro vol.41, pp.5, 2009, https://doi.org/10.14348/molcells.2018.2078
- The aberrantly expressed miR-372 partly impairs sensitivity to apoptosis in parathyroid tumor cells vol.25, pp.7, 2009, https://doi.org/10.1530/erc-17-0204
- A novel microRNA, hsa-miR-6852 differentially regulated by Interleukin-27 induces necrosis in cervical cancer cells by downregulating the FoxM1 expression vol.8, pp.None, 2009, https://doi.org/10.1038/s41598-018-19259-4
- Modulation of oncogenic miRNA biogenesis using functionalized polyamines vol.8, pp.None, 2009, https://doi.org/10.1038/s41598-018-20053-5
- Inhibition of miR‐24 suppresses malignancy of human non‐small cell lung cancer cells by targeting WWOX in vitro and in vivo vol.9, pp.12, 2009, https://doi.org/10.1111/1759-7714.12824
- Propofol suppresses growth, migration and invasion of A549 cells by down-regulation of miR-372 vol.18, pp.None, 2009, https://doi.org/10.1186/s12885-018-5175-y
- The E2F1–miR-520/372/373–SPOP Axis Modulates Progression of Renal Carcinoma vol.78, pp.24, 2009, https://doi.org/10.1158/0008-5472.can-18-1662
- Scenario and future prospects of microRNAs in gastric cancer: A review vol.22, pp.4, 2019, https://doi.org/10.22038/ijbms.2019.32399.7765
- MicroRNA-372-3p Predicts Response of TACE Patients Treated with Doxorubicin and Enhances Chemosensitivity in Hepatocellular Carcinoma vol.20, pp.None, 2020, https://doi.org/10.2174/1871520620666200516145830
- miR-205: A Potential Biomedicine for Cancer Therapy vol.9, pp.9, 2009, https://doi.org/10.3390/cells9091957
- Aminoglycoside Conjugation for RNA Targeting: Antimicrobials and Beyond vol.26, pp.54, 2020, https://doi.org/10.1002/chem.202002258
- Placenta-derived macaque trophoblast stem cells: differentiation to syncytiotrophoblasts and extravillous trophoblasts reveals phenotypic reprogramming vol.10, pp.1, 2009, https://doi.org/10.1038/s41598-020-76313-w
- Activation of the miR-371/372/373 miRNA Cluster Enhances Oncogenicity and Drug Resistance in Oral Carcinoma Cells vol.21, pp.24, 2009, https://doi.org/10.3390/ijms21249442
- Retracted: Targeted Regulation of FoxO3a by miR-372 to Mediate Gastric Carcinoma Cell Apoptosis and DDP Drug Resistance vol.35, pp.10, 2009, https://doi.org/10.1089/cbr.2019.3299
- Synthetic RNA Modulators in Drug Discovery vol.64, pp.11, 2021, https://doi.org/10.1021/acs.jmedchem.1c00154
- Design and Implementation of Synthetic RNA Binders for the Inhibition of miR-21 Biogenesis vol.12, pp.6, 2009, https://doi.org/10.1021/acsmedchemlett.0c00682
- Potential Biomarkers of miR-371-373 Gene Cluster in Tumorigenesis vol.11, pp.9, 2009, https://doi.org/10.3390/life11090984