The Korean Journal of Pain

The Korean Pain Society (대한통증학회)
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Implantation of an Intrathecal Drug Administration System -A report of two cases-

척수강 내 약물 주입기의 이식 -증례보고-

  • Lee, Sang Jin (Department of Anesthesiology and Pain Medicine, Seoul National University College of Medicine) ;
  • Nam, Sang Kun (Department of Anesthesiology and Pain Medicine, Seoul National University College of Medicine) ;
  • Kim, Jang Hyun (Department of Anesthesiology and Pain Medicine, Seoul National University College of Medicine) ;
  • Kim, Hyun Joo (Department of Anesthesiology and Pain Medicine, Seoul National University College of Medicine) ;
  • Lee, Sang Chul (Department of Anesthesiology and Pain Medicine, Seoul National University College of Medicine) ;
  • Kim, Yong Chul (Department of Anesthesiology and Pain Medicine, Seoul National University College of Medicine)
  • 이상진 (서울대학교 의과대학 마취과학교실) ;
  • 남상건 (서울대학교 의과대학 마취과학교실) ;
  • 김장현 (서울대학교 의과대학 마취과학교실) ;
  • 김현주 (서울대학교 의과대학 마취과학교실) ;
  • 이상철 (서울대학교 의과대학 마취과학교실) ;
  • 김용철 (서울대학교 의과대학 마취과학교실)
  • Received : 2008.12.24
  • Accepted : 2009.01.21
  • Published : 2009.04.01
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Abstract

Opioids profoundly inhibit evoked discharges of spinal nociceptive neurons, thereby inhibiting the transmission of pain. Intrathecal administration of opioids using implantable continuous infusion systems is an effective method of pain relief when other treatments have failed, as well as for patients with adequate analgesia on high dose therapy that produces unacceptable side effects. We report two cases of intrathecal pump implantation performed in patients suffering from intractable chronic pain. A test dose of 3 mg morphine was injected into the epidural space. No side effects were noted and patients experienced considerable pain relief. Implantation was performed one day after the test. The initial intrathecal morphine delivery dose was half of the equivalent dose of daily oral intake opioids and the infusion rate was increased gradually under close observation for opioid side effects. Two days post-implantation, both patients were discharged without any complications.

Keywords

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