대한한의학회지 (The Journal of Korean Medicine)

  • 제30권1호
  • /
  • Pages.128-136
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  • 2009
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  • 1010-0695(pISSN)
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  • 2288-3339(eISSN)
대한한의학회 (The Society of Korean Medicine)
권호 표지

한양방 병용치료를 받은 110명의 암 환자에 대한 후향적 조사연구

Study on 110 cancer patients treated by combination of Oriental and conventional treatment

  • 정태영 (대전대학교 한방병원 동서암센터) ;
  • 조정효 (대전대학교 한방병원 동서암센터) ;
  • 이종훈 (대전대학교 한방병원 동서암센터) ;
  • 조종관 (대전대학교 한방병원 동서암센터) ;
  • 유화승 (대전대학교 한방병원 동서암센터) ;
  • 손창규 (대전대학교 한방병원 동서암센터)
  • Jeong, Tae-Young (Department of East-West Cancer Center, Oriental Hospital of Daejeon University) ;
  • Cho, Jung-Hyo (Department of East-West Cancer Center, Oriental Hospital of Daejeon University) ;
  • Lee, Jong-Hoon (Department of East-West Cancer Center, Oriental Hospital of Daejeon University) ;
  • Cho, Chong-Kwan (Department of East-West Cancer Center, Oriental Hospital of Daejeon University) ;
  • Yoo, Hwa-Seung (Department of East-West Cancer Center, Oriental Hospital of Daejeon University) ;
  • Son, Chang-Gue (Department of East-West Cancer Center, Oriental Hospital of Daejeon University)
  • 발행 : 2009.01.30
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초록

Objective: To investigate a clinical worth of combination therapy of Oriental and conventional cancer treatment focusing on reduction of chemotherapy-induced side effects. Methods: 110 patients treated by Oriental treatment after intravenous or oral chemotherapy were reviewed, from January, 2005 to April, 2008 at the East-West Cancer Center of Dunsan Oriental hospital. Symptoms were investigated by National Cancer Institute-Common Toxicity Criteria (NCI-CTC) Version 2.0. Results: 80% patients of 110 patients had at least one symptom among eight main side effects (neutropenia, anorexia, nausea, vomiting, diarrhea, stomatitis, constipation, headache). The presence of those was as follows: nausea 63%, anorexia 61 %, neutropenia 45%, vomiting 28%, constipation 21 %, headache 19%, diarrhea 11 %, and stomatitis 10%. Except neutropenia, above symptoms has ameliorated by Oriental treatment in seven treat days. Conclusions: This study first presented the general characteristics of cancer patients treated by Oriental and conventional therapy, and showed a clinical potential of combinational therapy aiming to chemotherapy-induced side effects.

키워드

참고문헌

  1. Shin HR, Ahn YO, Bae JM, Shin MH, Lee DH, Lee CW et al. Cancer incidence in Korea. Cancer Res Treat 2003;34(6):405-8.
  2. Korean National Statistical Office. Statistics of moratlity returns according to causes. Available from: URL:http://www.kosis.kr
  3. Park KH, Kim SY, Chae HJ. Selection of Oriental Medicinal Plants for Screening of Anticancer Agents. Korean J. Biotechnol. Bioeng. 2007;22(3):139.
  4. 조종관, 유화승. 한의학의 암치료기술. 서울:의성당. 2006:75.
  5. Byun JL, Kim JS, Lee SN. Inhibition of Anticancer Chemotherapy - induced Stomatitis by Oral Cryotherapy. Journal of Korean Cancer Association. 1993;25:760-1.
  6. Cho SM, Chang JW, Moon HL, Hong YS, Kim HK, Kim HY et al. Control of Cancer Chemotherapy-induced Nausea and Vomiting. Journal of Korean Cancer Association. 1986;18:35-6.
  7. Han JY, Ann YB, Kang JH, Moon HL, Hong YS, Kim HK et al. Chemotherapy Induced Severe Neutropenia. Journal of Korean Cancer Association. 1993;25:602-3.
  8. Xin YF, Zhou GL, Deng ZY, Chen YX, Wu YG, Xu PS et al. Protective effect of Lycium barbarum on doxorubicin-induced cardiotoxicity. Phytother Res. 2007 Nov;21(11):1020-4. https://doi.org/10.1002/ptr.2186
  9. Dibble SL, Luce J, Cooper BA, Israel J, Cohen M, Nussey B et al. Acupressure for chemotherapyinduced nausea and vomiting: a randomized clinical trial. Oncology forum. 2007 Jul;34(4):813-20.
  10. Gardani G, Cerrone R, Biella C, Galbiati B, Proserpio E, Gasiraghi M et al. A case-control study of Panicum Miliaceum in the treatment of cancer chemotherapy-induced alopecia. Minerva med. 2007 Dec;98(6):661-4.
  11. Jeong MS, Jeong JY, Park HE, Lee CJ, Oh YL, Kim WG. A study of support-therapeutic effect and reducing side effect for high-dose vitamin C use of gynecological cancer patients with chemotherapy. Korean J Gynecol Oncol. 2007;18(2):93-4.
  12. National Cancer Institute. COMMON TOXICITY CRITERIA(CTC): version 2.0. 1999. http://ctep.cancer.gov./forms/ctcv2nom-4-30-99-final3.pdf.
  13. Park BK, Yoo HS, Lee YW, Han SS, Cho JH, Son CG et al. Retrospective Cohort Analysis for Lung Cancer Patients Treated with Wheel Balance Therapy(WBT). The Journal of Korean Oriental Internal Medicine. 2008:45-56.
  14. Yoo HS, Cho JH, Lee YW, Son CK, Cho CK. Case Study of Cancer Patients Treated with Herbal Acupuncture Therapy. Journal of Korean Institute of Herbal-Acupuncture. 2004;7:27-36.
  15. Kim HS, Hong SB, Sung HJ, Moon GA, Yoon YS. Effect of Deer Blood on Reduction of the Side Effects of Chemotherapeutic Drugs. Korean Journal of Pharmacognosy. 2003;34(2);145-9.
  16. Kim TW, Son CK, Cho CK. Studies on the effects of Sojeokbaekchoolsan on the bleomycin induced pulmonary fibrosis and the antitumor activity. The Journal of Korean Oriental Oncology. 1999;5(1):77-101.
  17. Cho CK. An anticancer effect and a influence upon reducing side effects of Cisplatin of Sojeok-baek-chul-san. The Journal of Korean Oriental Oncology. 1996;4(2):255-72.
  18. Shin JW, Lee MM, Son JY, Lee NH, Cho CK, Chung WK et al. Myelophil, a mixture of Astragali Radix and Salviae Radix extract, moderates toxic side effects of fluorouracil in mice. World J Gastroenterol. 2008;14(15):2323-8. https://doi.org/10.3748/wjg.14.2323
  19. Cho JH, Yoo HS, Lee YW, Son CK, Cho CK. Clinical study in 320 cases for cancer patients on the effect Hangamdan. Daejeon University, Institute of korean medicine. 2004;12:157-5.
  20. Choi BL, Son CK. The Clinical study in 62 cases for lung cancer patients on the effects by Hangamdan. Daejeon University, Institute of korean medicine. 2001;10:121-31.
  21. Song KC, Choi BL, Lee YY, Yoo HS, Seo SH, Choi WJ et al. The Clinical study in 60 cases for breast cancer patients on the effects by Hnagamdan. The Journal of Korean Oriental Internal Medicine. 2001;22(4):669-74.
  22. Choi WJ, Son CK, Cho CK. The Clinical Report of PSM about 121 Cancer Patients. Korean Journal of Oriental Physiology and Pathology. 2001;15(2):361-6.
  23. Christine M, Lindsay M, Kristan M. The washington manual of oncology. Selected chemotherapy regimens. Philadelphia, USA:Lippincott Williams & Wilkins. 2008:497-533.
  24. Cho SM, Chang JW, Moon HL, Hong YS, Kim HK, Kim HY et al. Control of Cancer Chemotherapy-induced Nausea and Vomiting. Journal Korean Cancer Research Association. 1986;18;35-40.
  25. Lee KS, Han JY, Moon HL, Lee BG, Cho SK, Jin JR et al. Comparison of Tropisetron with Ondansetron in the Preventon of Cisplatin-induced Nausea and Vomiting. Journal of Korean Cancer Association. 1997;29(2):332-9.
  26. Park SW, Lee SH, Kim YJ, Kim KH, Yoon MS, Kim WW. A randomized comparison of intravenous ondansetron alone and in combination with intravenous dexamethasone in prevention of Nausea and Vomiting associated with Cisplatin based combination chemotherapy. J Korean Obstetrics and Gynecol. 1996;39(8):1523-32.
  27. Lee KJ, Moon SM, Hwang DY. Hematologic and Non-hematologic Toxicity after Intravenous Adjuvant 5-Fluorouracil and Leucovorin Treatment of Colorectal Cancer: A Prospective Study. J Korean Soc Coloproctol. 2005;21(6):426-32.
  28. 최경업, 김은영. 항암요법제의 임상약동력학. 서울:군자출판사. 2006:58-9,128,214-5.
  29. 박재갑, 박찬일, 김노경. 종양학. 서울:일조각. 2007:148,161,170.
  30. SM Chow. Side effect of high-dose radioactive iodine for ablation or treatment of differentiated thyroid carcinoma. J HK Coll Radiol. 2005;8:127-35.
  31. Yoon DH, Lee NH, Shim JC, Chae EY, Yoo HS, Cho JH et al. Study of Efficiency of the Eastwest Medical Combined Treatment of Advanced Gastric Cancer in Patients Case. Korean Journal of Oriental Physiology and Pathology. 2005;19(6):1681-4.
  32. Kim CB, Yoo JS, Park JK, Koh KW, Choi SY. Combined Treatment of Oriental Herbal Medicine and Prescribed Drugs among Cancer Patients. J Korean Oriental Med. 2007;28(2):205-12.