Bulletin of the Korean Chemical Society

Korean Chemical Society (대한화학회)
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Molecular Recognition of Neutral Substrates by New Tetraaminocalix[4]arene Derivative

  • Nimse, Satish Balasaheb (Institute for Applied Chemistry and Department of Chemistry, Hallym University) ;
  • Song, Keum-Soo (Biometrix Technology, Inc., 202 BioVenture Plaza) ;
  • Jung, Chan-Yong (Biometrix Technology, Inc., 202 BioVenture Plaza) ;
  • Eoum, Woon-Yong (Biometrix Technology, Inc., 202 BioVenture Plaza) ;
  • Kim, Tai-Sun (Institute for Applied Chemistry and Department of Chemistry, Hallym University)
  • Published : 2009.06.20
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Abstract

The recognition of neutral aromatic substrates by different neutral calix[4]arene receptors 1, 2, and 3 was studied by NMR spectroscopy. The stoichiometry is 1:1 in all cases as was confirmed by jobs plot. Owing to the deep cavity, 1 affords stronger binding abilities for substrate 4 and 5, while all receptors remained inert for substrates 6 and 7. The binding constants determined by $^1H$ NMR titration show that the recognition of substrate 4 by 1 gives strongest complexation ($K_a\;of\;9.8\;{\times}\;102\;M^{-1}$).

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