Bulletin of the Korean Chemical Society

Korean Chemical Society (대한화학회)
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Topological Study of the Behavior of Inorganic Fine Powers and a Nanovesicle Hybridized Coating

  • Seo, Dong-Sung (Department of Fine Chemical Engineering & Chemistry, Chungnam National University) ;
  • Kim, Dong-Pyo (Department of Fine Chemical Engineering & Chemistry, Chungnam National University) ;
  • Jin, Fan-Long (School of Chemical and Materials Engineering, Jilin Institute of Chemical Technology) ;
  • Park, Soo-Jin (Department of Chemistry, Inha University)
  • Published : 2009.02.20
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Abstract

In this study, the surface of inorganic fine powders is hybridized with nanovesicles containing tocopheryl acetate prepared with hydrogenated lecithin via a coating process. From AFM and SEM analyses it is found that the surface of the nanovesicle-coated fine powders lost their traditional topology and improved in terms of their roughness, skewness, and kurtosis. In addition, TEM observations revealed the formation of a 5 nm thick coating layer on the surface of the fine powders. These hybridized powders, in which bioactive materials such as tocopheryl acetate can be embedded, can be employed as a part of a drug delivery system due to their special ability to control release rate and temperature selectivity. Physical properties of the powders, i.e., the different angle and friction coefficient, were excellent.

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