DOI QR코드

DOI QR Code

Chemical Components of Dendrobium polyanthum

  • Hu, Jiang-Miao (State Key Laboratory of Phytochemistry and Plant Resource in West China, Kunming Institute of Botany, The Chinese Academy of Science) ;
  • Zhao, You-Xing (State Key Laboratory of Phytochemistry and Plant Resource in West China, Kunming Institute of Botany, The Chinese Academy of Science) ;
  • Miao, Ze-Hong (Division of Anti-Tumor Pharmacology, Shanghai Institute of Materia Medica, The Chinese Academy of Sciences) ;
  • Zhou, Jun (State Key Laboratory of Phytochemistry and Plant Resource in West China, Kunming Institute of Botany, The Chinese Academy of Science)
  • Published : 2009.09.20

Abstract

A new tetrahydroanthracene, 3,6,9-trihydroxy-3,4-dihydroanthracen-1(2H)-one (1), six phenolics, moscatilin (2), gigantol (3), batatasin (4), moscatin (5), 9,10-dihydromoscatin (6), 10-dihydrophenanthrene-2,4,7-triol (7), and a sesquiterpenoid, corchoionoside C (8), together with two sterols $\beta$-sitosterol (9) and daucosterol (10), were isolated from the stems of Dendrobium polyanthum. Compounds 1 and 2 were assessed for cytotoxic activity against two human tumor cell lines (A549 and HL-60).

Keywords

References

  1. Jiangsu New Medicinal University, Dictionary of Chinese Medicines; Shanghai Scientific and Technical Publishers: 1986; p 586
  2. Editing Committee of the Pharmacopoeia of China, Pharmacopoeia of China, Part Ι; Chemistry and Industry Press: 2005; p 62
  3. Ye, Q. H.; Zhao, W. M.; Qin, G. W. In The Progress in Medicinal Chemistry; Peng, S. X., Ed.; Chemical Industry Press: 2002; vol. 3, p 113
  4. Editing Committee of the Flora of China, Flora of China; Science press: 1999; Vol. 19, p 67
  5. Hu, J. M.; Chen, J. J.; Yu, H.; Zhao, Y. X.; Zhou, J. Journal of Asian Natural Products Research 2008, 10, 647 https://doi.org/10.1080/10286020802133605
  6. Hu, J. M.; Chen, J. J.; Yu, H.; Zhao, Y. X.; Zhou, J. Planta Medica 2008, 74, 535 https://doi.org/10.1055/s-2008-1074492
  7. Luning, B.; Leander, K. Acta Chemica Scandinavica 1965, 19, 1607 https://doi.org/10.3891/acta.chem.scand.19-1607
  8. Blomqvist, L.; Leander, K.; Luning, B.; Rosenblom, J. Acta Chemica Scandinavica 1972, 26, 3203 https://doi.org/10.3891/acta.chem.scand.26-3203
  9. Yenesew, A.; Ogur, J. A.; Duddeck, H. Phytochemistry 1993, 34, 1442 https://doi.org/10.1016/0031-9422(91)80049-7
  10. Yagi, A.; Makino, K.; Nishioka, I. Chemical & Pharmaceutical Bulletin 1974, 22, 1159 https://doi.org/10.1248/cpb.22.1159
  11. Bell, A. A.; Stipanovic, R. D.; Puhalla, J. E. Tetrahedron 1976, 32, 1353 https://doi.org/10.1016/0040-4020(76)85009-0
  12. Fabrice, V.; Michel, G. Tetrahedron 1990, 46, 2827 https://doi.org/10.1016/S0040-4020(01)88375-7
  13. Majumder, P. L.; Sen, R. C. Phytochemistry 1987, 26, 2121 https://doi.org/10.1016/S0031-9422(00)81777-X
  14. Leslie, C.; Jamieson, S. V. J. Chem. Soc., Perkin Trans Ι 1982, 7, 1467
  15. Majumder, P. L.; Pal, S. Phytochemistry 1993, 32, 1561 https://doi.org/10.1016/0031-9422(93)85180-Y
  16. Anton, H.; Schoeneborn, R.; Mues, R. Phytochemistry 1999, 52, 1639 https://doi.org/10.1016/S0031-9422(99)00394-5
  17. Coxon, D. T.; Ogundana, S. K.; Dennis, C. Phytochemistry 1982, 21, 1389 https://doi.org/10.1016/0031-9422(82)80148-9
  18. Honda, C.; Yamaki, M. Phytochemstry 2000, 53, 987 https://doi.org/10.1016/S0031-9422(99)00497-5
  19. Bhaskar, M. U.; Rao, L. J. M.; Rao, N. S. P.; Rao, P. R. M. J. Nat. Prod. 1991, 54, 386 https://doi.org/10.1021/np50074a006
  20. Sawabe, A.; Nesumi, C.; Morita, M.; Matsumoto, S.; Matsubara, Y.; Komemushi, S. J. Oleo Science 2005, 54, 185 https://doi.org/10.5650/jos.54.185
  21. Çalıs, I.; Kuruüzüm-Uz, A.; Lorenzetto, P. A.; Rüedi, P. Phytochemistry 2002, 59, 451 https://doi.org/10.1016/S0031-9422(01)00399-5
  22. Lee, Y. H.; Park, J. D.; Baek, N. I.; Kim, S. I.; Ahn, B. Z. Planta Medica 1995, 61, 178 https://doi.org/10.1055/s-2006-958043
  23. Gong, Y. Q.; Fan, Y.; Wu, D. Z.; Yang, H.; Hu, Z. B.; Wang, Z. T. European Journal of Cancer 2004, 40, 1554 https://doi.org/10.1016/j.ejca.2004.01.041

Cited by

  1. ChemInform Abstract: Chemical Components of Dendrobium polyanthum vol.41, pp.6, 2010, https://doi.org/10.1002/chin.201006201
  2. )-ones vol.14, pp.14, 2012, https://doi.org/10.1021/ol301305p
  3. Chemistry, bioactivity and quality control of Dendrobium, a commonly used tonic herb in traditional Chinese medicine vol.12, pp.2, 2013, https://doi.org/10.1007/s11101-013-9310-8
  4. Chemical components of Dendrobium crepidatum and their neurite outgrowth enhancing activities vol.3, pp.2, 2013, https://doi.org/10.1007/s13659-012-0103-3
  5. A New 9,10-Dihydrophenanthrene Glycoside from Dendrobium primulinum vol.52, pp.3, 2016, https://doi.org/10.1007/s10600-016-1653-0
  6. Chemical Components of Dendrobium chrysotoxum vol.30, pp.6, 2012, https://doi.org/10.1002/cjoc.201100670
  7. Chemical constituents from Dendrobium brymerianum Rchb. f vol.57, pp.None, 2009, https://doi.org/10.1016/j.bse.2014.08.027