The Korean Journal of Cytopathology (대한세포병리학회지)

The Korean Society for Cytopathology (대한세포병리학회)
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Mucinous Tubular and Spindle Cell Carcinoma of the Kidney: Touch Imprint Cytologic and Histologic Findings - A Case Report -

점액성 세관 방추세포 신장암종의 압착도말 세포소견 - 1예 보고 -

  • Won, Kyu-Yeoun (Department of Pathology, East-West Neo Medical center, School of Medicine, Kyunghee University) ;
  • Kim, Gou-Young (Department of Pathology, East-West Neo Medical center, School of Medicine, Kyunghee University) ;
  • Lim, Sung-Jig (Department of Pathology, East-West Neo Medical center, School of Medicine, Kyunghee University) ;
  • Kim, Hyun-Cheol (Department of Radiology, East-West Neo Medical center, School of Medicine, Kyunghee University) ;
  • Jeon, Seung-Hyun (Department of Urology, East-West Neo Medical center, School of Medicine, Kyunghee University)
  • 원규연 (경희대학교 동서신의학병원 병리과) ;
  • 김교영 (경희대학교 동서신의학병원 병리과) ;
  • 임성직 (경희대학교 동서신의학병원 병리과) ;
  • 김현철 (경희대학교 동서신의학병원 영상의학과) ;
  • 전승현 (경희대학교 동서신의학병원 비뇨기과)
  • Published : 2008.09.30
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Abstract

The recent WHO classification has recognized mucinous tubular and spindle cell carcinoma (MTSCC) as a distinct entity of renal cell carcinoma, exhibiting a mixed pattern of tubules and a surrounding spindle cell proliferation within a myxoid stroma, with low-grade nuclear features. A 51-year-old woman had an incidentally discovered renal mass. Radiologic examination revealed a large, well defined mass in the lower pole of the right kidney; a right radical nephrectomy was performed. Imprint cytologic smears from fresh surgical specimens showed cellular, cohesive clusters with thick, broad trabecular arrangements and branching structures. On high power fields, the tumor was composed of round-to-oval low-grade nuclei with vesicular chromatin and small nucleoli. The tumor cells had indistinct borders and pale, eosinophilic cytoplasm, In some areas, round-to-elongated tubular structures and spindle cell patterns were noted. Chronic inflammatory cell infiltration was noted, along with a mucinous back-ground and occasional psammoma bodies. Neither significant cytologic atypia nor mitosis was seen.

Keywords

References

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  1. Mucinous Tubular and Spindle Cell Carcinoma of the Kidney with Aggressive Behavior: An Unusual Renal Epithelial Neoplasm - A Case Report - vol.44, pp.2, 2008, https://doi.org/10.4132/koreanjpathol.2010.44.2.211