Food Science of Animal Resources (한국축산식품학회지)

Korean Society for Food Science of Animal Resources (한국축산식품학회)
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Neuroprotective Effects and Physicochemical Characteristics of Milk Fortified with Fibroin BF-7

BF-7 강화 우유의 뇌기능보호 효과 및 물리화학적 특성

  • Choi, Gooi-Hun (Division of Animal Life Science, Konkuk University) ;
  • Jo, Mi-Na (Division of Animal Life Science, Konkuk University) ;
  • Moon, Sun-Hee (Division of Animal Life Science, Konkuk University) ;
  • Lim, Sung-Min (Division of Animal Life Science, Konkuk University) ;
  • Jung, A-Ram (Division of Animal Life Science, Konkuk University) ;
  • Yoon, Yoh-Chang (Division of Animal Life Science, Konkuk University) ;
  • Paik, Hyun-Dong (Division of Animal Life Science, Konkuk University)
  • 최귀헌 (건국대학교 동물생명과학부) ;
  • 조미나 (건국대학교 동물생명과학부) ;
  • 문선희 (건국대학교 동물생명과학부) ;
  • 임성민 (건국대학교 동물생명과학부) ;
  • 정아람 (건국대학교 동물생명과학부) ;
  • 윤여창 (건국대학교 동물생명과학부) ;
  • 백현동 (건국대학교 동물생명과학부)
  • Published : 2008.10.31
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Abstract

The impact of storage on the neuroprotective effects against $A\beta$-induced cell death and physicochemical characteristics of milk fortified with BF-7 were investigated. The BF-7 milk exerted protection of neuronal cells SK-N-SH from amyloid beta ($A\beta$)-induced neuronal stress. Our results showed that incubation of the cell with pretreated BF-7 milk, significantly attenuated apoptotic stress by $A\beta$, considered in cell morphology and nucleus shape. The general compositions were maintained consistently in BF-7 fortified milk (BF-7 milk). The BF-7 did not make any disturbance on pH and titratable acidity. The color change was not detected, either. Also, any microorganism had not been detected with more than 7 days storage at $4^{\circ}C$. In sensory evaluation study. the average scores of each sensory attribute were quite similar with plain milk. In conclusion, our results strongly indicate that BF-7 characteristics are quite adequate to be included in milk and BF-7 milk is still working well on neuro-protection, result in enforcing our brain and delaying neurodegeneration.

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References

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