The Korean Journal of Food And Nutrition (한국식품영양학회지)

The Korean Society of Food and Nutrition (한국식품영양학회)
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Effect of Gastrodiae rhizoma Powder on Serum and Liver Lipid Levels of Rats with High Fat Diet

고지방 식이와 병행 섭취한 천마 분말이 흰쥐의 혈청 및 간 조직 지질 함량에 미치는 영향

  • Cho, Hwa-Eun (Dept. of Professional Graduate School of Oriental Medicine, Wonkwang University) ;
  • Choi, Yun-Hee (Dept. of Professional Graduate School of Oriental Medicine, Wonkwang University) ;
  • Park, Sung-Hye (Dept. of School of Industrial Technology, Myungji University) ;
  • Park, Yong-Soo (Dept. of MJ Health Foods Association) ;
  • Ahn, Byung-Yong (School of Environmental and Resource, Chonbuk National University)
  • 조화은 (원광대학교 한의학전문대학원 한방건강증진연구개발팀) ;
  • 최윤희 (원광대학교 한의학전문대학원 한방건강증진연구개발팀) ;
  • 박성혜 (명지대학교 산업대학원 식품양생학과) ;
  • 박용수 (무주군약초영농조합법인) ;
  • 안병용 (전북대학교 환경자원학부)
  • Published : 2008.03.31
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Abstract

This study was performed to study the effects of Gastrodiae rhizoma on lipid concentration of serum and liver in rats fed high fat diet. Male Sprague-Dawley rat were randomly assigned to 5 groups such as basal diet only(BDG), high fat diet(HFG) and high fat diet with 5% processed Gastrodiae rhizoma(GRL), high fat diet with 10% processed Gastrodiae rhizoma(GRM), high fat diet with 15% processed Gastrodiae rhizoma(GRH) supply each of the experimental diets for 6 weeks. Food intake was significantly decreased by both high fat intake and high fat with Gastrodiae rhizoma intake compared with basal diet intake but weight gain was not significantly different from each groups. Liver weights were significantly lowered by Gastrodiae rhizoma intake compared with high fat intake. In the serum, total cholesterol was not significantly different with each groups, but triglyceride level was significantly lowered by Gastrodiae rhizoma intake as compared with control. In the liver, lipid levels inceased with the Gastrodiae rhizoma intake, but total cholesterol and triglyceride levels were not significantly different with control. These results showed that dietary Gastrodiae rhizoma as supplementary food may decrease triglyceride in the serum.

Keywords

References

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