The Korean Journal of Food And Nutrition (한국식품영양학회지)

The Korean Society of Food and Nutrition (한국식품영양학회)
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The Anticoagulant and Anticancer Activities of Enteromorpha intestinalis Extracts

파래 추출물의 항응고 활성과 항암 활성에 관한 연구

  • Lim, Eun-Jeong (Dept. of Food and Nutrition, Hanyang Women's College) ;
  • Cho, Kyung-Ryun (Dept. of Food and Nutrition, Hanyang Women's College) ;
  • Kim, Ji-Young (Dept. of Food and Nutrition, Hanyang Women's College) ;
  • Lee, Yoo-Hyun (Dept. of Food and Nutrition, Suwon University) ;
  • Ho, Jin-Nyoung (Laboratory of Radiation Tumor Physiology, Korea Institute of Radiological and Medical Sciences) ;
  • Kim, Young-Jun (Dept. of Food and Biotechnology, Korea University) ;
  • Cho, Hong-Yon (Dept. of Food and Biotechnology, Korea University)
  • 임은정 (한양여자대학 식품영양과) ;
  • 조경련 (한양여자대학 식품영양과) ;
  • 김지영 (한양여자대학 식품영양과) ;
  • 이유현 (수원대학교 식품영양학과) ;
  • 효진녕 (한국원자력의학원 방사선종양연구부) ;
  • 김영준 (고려대학교 식품생명공학과) ;
  • 조홍연 (고려대학교 식품생명공학과)
  • Published : 2008.03.31
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Abstract

The study was performed to investigate the biological activity of Enteromorpha intestinalis. In order to examine its blood anti-coagulant effects, Enteromorpha intestinalis was extracted with cold water, methanol, hot water, HCl and NaOH. In general, the alkali extract of Enteromorpha intestinalis was approximately 17 times stronger than the control. The anti-cancer effects of select extracts(methanol, hot water, 0.1 N NaOH, 1 N NaOH) were determined in human melanoma cells(Bl6/F10), fibrosarcoma cells(HTl080) and breast cancer cells(MCF7) by MTT assay. With the treatment of 250 ${\mu}g/m{\ell}$ of methanol extracts. HT1080, B16/F10 and MCF7 cell viabilities significantly decreased to 8.06%, 3.62% and 10.10%, respectively. Thus these results strongly support the possibie use of Enteromorpha intestinalis as a functional materials.

Keywords

References

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