한국어병학회지 (Journal of fish pathology)

  • 제21권3호
  • /
  • Pages.219-228
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  • 2008
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  • 1226-0819(pISSN)
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  • 2233-5412(eISSN)
한국어병학회 (The Korean Society of Fish Pathology)
권호 표지

Yeast $\beta$-glucan 첨가 사료가 뱀장어의 비특이적 면역 반응에 미치는 영향

The Effects of yeast $\beta$-glucan in the Diet on Immune Response of Japanese eel, Anguilla japonica, by Oral Administration

  • 김진도 (국립수산과학원 남부내수면연구소) ;
  • 우승호 (부경대학교 수산생명의학과) ;
  • 김이청 (국립수산과학원 남부내수면연구소) ;
  • 이준희 (부경대학교 수산생명의학과) ;
  • 조용철 (국립수산과학원 남부내수면연구소) ;
  • 최상민 (국립수산과학원 남부내수면연구소) ;
  • 박수일 (부경대학교 수산생명의학과)
  • Kim, Jin-Do (Inland Aquaculture Research Institute, National Fisheries Research & Development Institute (NFRDI)) ;
  • Woo, Sung-Ho (Department of Aquatic life medicine, Pukyong National University) ;
  • Kim, Yi-Cheong (Inland Aquaculture Research Institute, National Fisheries Research & Development Institute (NFRDI)) ;
  • Lee, Jun-Hee (Department of Aquatic life medicine, Pukyong National University) ;
  • Cho, Yong-Chul (Inland Aquaculture Research Institute, National Fisheries Research & Development Institute (NFRDI)) ;
  • Choi, Sang-Min (Inland Aquaculture Research Institute, National Fisheries Research & Development Institute (NFRDI)) ;
  • Park, Soo-Il (Department of Aquatic life medicine, Pukyong National University)
  • 발행 : 20081200
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초록

The effects of dietary yeast β-glucan administration on growth, nonspecific immune responses, serum lysozyme, skin mucous lysozyme, NBT (nitroblue tetrazolium) reduction by phagocytes, and disease resistance against Edwardsiella tarda in Japanese eel, Anguilla japonica were evaluated. Fish were fed the diets supplemented with 0%, 0.1% and 0.5% of yeast β-glucan to a commercial diet for 6 weeks. The body weight gain from the fish fed on the 0.5% supplemented diet for 6 weeks was significantly higher than the control. Both serum and skin mucous lysozyme were significantly higher in the all experimental groups except 2 weeks of 0.5% group. The bactericidal activity of serum was slightly increased at 6 weeks. Also, The intracellular superoxide anion production of kidney phagocytes was significantly higher in the all experimental groups. The diet supplemented with 0.1% were also found to raise the relative percent survival (RPS) of Japanese eel after an artificial challenge with 1×107 cells of Edwardsiella tarda per fish. The results suggested the potential of yeast β-glucan to activate some innate immune responses and to improve the growth in Japanese eel.

키워드

참고문헌

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