대한임상독성학회지 (Journal of The Korean Society of Clinical Toxicology)
- 제6권2호
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- Pages.138-141
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- 2008
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- 1738-1320(pISSN)
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- 2508-6332(eISSN)
위장관염으로 오인된 콜히친 중독 1례
A Case of Colchicine Intoxication Presenting as Acute Gastroenteritis
- 안지윤 (한림대학교 의과대학 응급의학교실) ;
- 손유동 (한림대학교 의과대학 응급의학교실) ;
- 권혁술 (한림대학교 의과대학 응급의학교실) ;
- 안희철 (한림대학교 의과대학 응급의학교실)
- Ahn, Ji-Yun (Department of Emergency Medicine, College of Medicine, Hallym University) ;
- Sohn, You-Dong (Department of Emergency Medicine, College of Medicine, Hallym University) ;
- Kwon, Hyuk-Sool (Department of Emergency Medicine, College of Medicine, Hallym University) ;
- Ahn, Hee-Chol (Department of Emergency Medicine, College of Medicine, Hallym University)
- 발행 : 2008.12.31
초록
A 47-year-old woman ingested about 12 mg of colchicine with suicidal intent. Colchicine, a highly poisonous alkaloid, is a commonly used treatment for gout, Bechet's disease, and familial Mediterranean fever. Despite the knowledge of its side effects, the risk of a significant overdose is under-appreciated. She suffered from acute multisystem toxicity, including gastrointestinal disorders, bone marrow suppression, alopecia, and probable pancreatitis, but she ultimately recovered with supportive therapy. We report a case of acute colchicine toxicity from a single overdose with a review of the literature.