한국동물위생학회지 (Korean Journal of Veterinary Service)

  • 제31권3호
  • /
  • Pages.291-303
  • /
  • 2008
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  • 3022-7372(pISSN)
  • /
  • 2287-7630(eISSN)
한국동물위생학회 (The Korean Society of Veterinary Service)
권호 표지

돼지 마이코플라즈마 폐렴 예방백신의 접종시기별 방어효과에 관한 연구

Evaluation of vaccination against Mycoplasma hyopneumoniae in pigs at different vaccination time-points

  • Lee, Ham-Hee (Cargill Agri Purina) ;
  • Rha, James (Graduate School of Public Health, Seoul National University) ;
  • Han, Jeong-Hee (Kangwon National University, Department of Veterinary Medicine)
  • 발행 : 2008.09.30
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초록

This study was performed to evaluate the effect of commercial swine mycoplasma vaccine (M+$Pac^{(R)}$, Schering-Plough Animal HealthCo.) at different vaccination time points. Total 139 piglets were moved to experimental farm after weaning and were randomly allocated to 3 treatment groups and 1 control group. Piglets of 3 treatment groups (A, B and C) were vaccinated twice at 1 and 3 weeks (A group), 3 and 5 weeks (B), and 6 and 8 weeks (C), respectively. All vaccinates showed higher antibody titers compared with nonvaccinates, and maintained to finish (P<0.001). Performance and RBC/WBC count showed no significant difference between groups. Vaccinates at 6-8 weeks showed better effect on decrease of clinical sign compared with vaccinates at 1-3 weeks and 3-5 weeks and nonvaccinates. Also, lung lesion assessment showed significant difference between vaccinates at 3-5 weeks and 6-8 weeks, and nonvaccinates and vaccinates at 1-3 weeks (P<0.05). Vaccinates at 3-5 score in comparison with other groups. In conclusion, these results suggested that vaccination at 3-5 weeks or later may be more effective than earlier vaccination.

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