Phenolic Constituents of Althaea rosea Canival.

접시꽃뿌리의 페놀성 성분

  • Kim, Do-Hoon (Natural Pruducts Laboratory, College of Pharmacy, Sungkyunkwan University) ;
  • Yang, Min-Cheol (Natural Pruducts Laboratory, College of Pharmacy, Sungkyunkwan University) ;
  • Lee, Kyu-Ha (Natural Pruducts Laboratory, College of Pharmacy, Sungkyunkwan University) ;
  • Kim, Ki-Hyun (Natural Pruducts Laboratory, College of Pharmacy, Sungkyunkwan University) ;
  • Lee, Kang-Ro (Natural Pruducts Laboratory, College of Pharmacy, Sungkyunkwan University)
  • 김도훈 (성균관대학교 약학대학 천연물 약품화학 연구실) ;
  • 양민철 (성균관대학교 약학대학 천연물 약품화학 연구실) ;
  • 이규하 (성균관대학교 약학대학 천연물 약품화학 연구실) ;
  • 김기현 (성균관대학교 약학대학 천연물 약품화학 연구실) ;
  • 이강노 (성균관대학교 약학대학 천연물 약품화학 연구실)
  • Published : 2007.09.30

Abstract

Seven compounds, scopoletin (1), p-hydroxyphenethyl trans-ferulate (2), $1-({\alpha}-L-rhamnosyl(1\;{\rightarrow}\;6)-{\beta}-D-glucopyranosyloxy)-3,4,5-trimethoxybenzene$ (3), benzyl ${\alpha}-L-rhamnopyranosyl(1\;{\rightarrow}\;6)-{\beta}-D-glucopyranoside$ (4), suberic acid (5), sebacic acid (6) and scopolin (7) were isolated from the methanol extract of the roots of Althaea rosea Canival. Compounds $1\;{\sim}\;7$ were first isolated from this plant. The isolated compounds were tested for their cytotoxicity against human cancer cell lines using a SRB method in vitro.

Keywords

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