Korean Journal of Pharmacognosy (생약학회지)

The Korean Society of Pharmacognosy (한국생약학회)
권호 표지

Quantitative and Pattern Analysis of Aucklandia lappa Decne and Inula helenium L.

목향과 토목향의 성분함량과 패턴비교 연구

  • Lee, A-Yeong (Department of Herbal Resources Research, Korea Institute of Oriental Medicine) ;
  • Chun, Jin-Mi (Herbal Quality Control Team, Korea Institute of Oriental Medicine) ;
  • Lee, Hye-Won (Department of Herbal Resources Research, Korea Institute of Oriental Medicine) ;
  • Choo, Byung-Kil (Department of Herbal Resources Research, Korea Institute of Oriental Medicine) ;
  • Kim, Ho-Kyoung (Department of Herbal Resources Research, Korea Institute of Oriental Medicine)
  • 이아영 (한국한의학연구원 한약자원연구부) ;
  • 천진미 (한국한의학연구원 한약품질검사팀) ;
  • 이혜원 (한국한의학연구원 한약자원연구부) ;
  • 추병길 (한국한의학연구원 한약자원연구부) ;
  • 김호경 (한국한의학연구원 한약자원연구부)
  • Published : 2007.09.30
Download PDF
⟨ Previous Next ⟩

Abstract

Aucklandia lappa Decne (Compositae) has been used for treatment of vomiting, diarrhea, abdominal pain and indigestion and Inula helenium L. (Compositae) for sweat and urination. In spite of difference species and efficacy, we have been used Aucklandia lappa Dence together with Inula helenium L. To distinguish Aucklandia lappa Dence from Inula helenium L., we have compared the contents of dehydrocostuslactone and costunolide by HPLC. The average contents of costunolide of Aucklandia lappa Dence was 0.84% $({\pm}\;0.29)$ but was not detected in Inula helenium L. The contents of dehydrocostuslactone from Aucklandia lappa Dence and Inula helenium L. were about 1.70% $({\pm}0.37)$ and 1.82% $({\pm}0.59)$, respectively.

Keywords

References

  1. 식품의약품안전청 (2002) 대한약전, 메디칼인덱스사, 22- 23, 86, 서울
  2. Association of phytology professor (2004) Phytology, Younglim Press, 353-354, 366-367, Seoul
  3. Jung, J. H., Ha, J. Y., Min, K. R., Shibata, F., Nakagawa, H., Kang, S. S., Chang, I. M. and Kim, Y. S. (1998) Reynosin from Saussurea lappa as inhibitor on CINC-1 induction in LPS-stimulated NRK-52E. Cells Planta Med. 64: 454-456 https://doi.org/10.1055/s-2006-957480
  4. Jung, J. H., Kim, Y. S., Lee, C. O., Kang S. S., Park, J. H. and Im, K. S. (1998) Cytotoxcity constituents of Saussurea lappa. Arch. Pharm. Res. 21: 153-156 https://doi.org/10.1007/BF02974020
  5. Kang, S. S., Kim, J. S., Chi, H. J., Chang S. Y. and Ha, K. W. (1999) Isolation and quantitative determination of costunolide from Saussurea Root. Kor. J. Pharmacogn. 30: 48- 53
  6. Chen, H. C., Chou, C. K., Lee, S. D, Whang, J. C., and Yeo, S. F. (1995) Active compounds from Saussurea lappa Clarks that supress hepatitis B virus surface antigen gene expression in human hepatoma cells. Antiviral Res. 27: 99-109 https://doi.org/10.1016/0166-3542(94)00083-K
  7. Wedge, D. E., Galindo, J. C. and Macias, F. A. (2000) Fungicidal activity of natural and synthetic sesquiterpene lactone analogs. Phytochem. 53: 747-757 https://doi.org/10.1016/S0031-9422(00)00008-X
  8. Park, H. J., Jung, W. T., Basnet, P., Kadota, S. and Namba, T. (1996) Syringin 4-O-beta-glucoside a new pheylpropanoid glycoside and costunolide, a nitric oxide synthesis inhibitor from the stem bark of Magnolia sieboldii. J. Nat. Prod. 59: 1128-1130 https://doi.org/10.1021/np960452i
  9. Matsuda, H., Toguchida, I., Ninomiya, K., Kageura, T., Morikawa, T. and Yoshikawa, M. (2003) Effects of sesquiterpenes and amino acid-sesquiterpene conjugates from the roots of Saussurea lappa on inducible nitric oxide synthesis and heat shock protein in lipopolysaccharide-activated macrophages. Bioorg. Med. Chem. 11: 709-715 https://doi.org/10.1016/S0968-0896(02)00471-6
  10. Choi, J. H., Seo, B. R., Seo, S. H., Lee, K. T., Park, J. H., Park, H. J., Choi, J. W., Itoh, Y. and Miyamoto, K. (2002) Costunolide induces differentiation of human leukemia HL- 60 cells. Arch. Pharm. Res. 25: 480-484 https://doi.org/10.1007/BF02976606
  11. Jeon, Y. J., Lee, H. S., Yeon, S. W., Ko, J. H., An, K. M., Yu, S. W., Kang, J. H., Hwang, B. Y. and Kim, T. Y. (2005) Inhibitory effects of dehydrocostuslactone isolated from Saussureae Radix on CDK2 activity. Kor. J. Pharmacogn. 36(2): 97-101
  12. Wang K., Liu H., Zhao Y., Chen X., Hu Z., Song Y. and Ma X. (2000) Separation and determination of alantolactone and isoalantolactone in traditional Chinese herbs by capillary electrophoresis. Talanta. 52: 1001-1005 https://doi.org/10.1016/S0039-9140(00)00467-7
  13. Soh, C. T., Oh, H. S. and Kim, N. S. (1980) Effect of Lysimachia clethroides in vitro on several trematodes and nematodes. Yonsei Rep. Trop. Med. 11: 58
  14. Ahn, B. J. and Rhee, J. K. (1986) Anthelmintic natural products against clonorchis sinensis and the analogues. Yakhak Hoeji. 30(5): 253-265
  15. 중화인민공화국 (1995) 중화인민 공화국약전, 화학공업출판사, 12, 47, 북경
  16. 식품의약품안전청 (2002) 대한약전, 메디칼인덱스사, 1654- 1656, 서울