Journal of Life Science (생명과학회지)

Korean Society of Life Science (한국생명과학회)
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Antioxidative Activity and Nitrite Scavenging Effect of the Composites Containing Medicinal Plant Extracts

한약재 조성물의 항산화 활성 및 아질산염 소거능

  • Cho, Hee-Sook (Department of Arts, Woosong University) ;
  • Lee, Soo-Jung (Department of Food Science and Nutrition, Institute of Agriculture and Life Science, Gyeongsang National University) ;
  • Shin, Jung-Hye (Department of Hotel Curinary Arts & Bakery, Namhae College) ;
  • Kang, Min-Jung (Department of Food Science and Nutrition, Institute of Agriculture and Life Science, Gyeongsang National University) ;
  • Cho, Hyun-So (Department of Food Science and Nutrition, Institute of Agriculture and Life Science, Gyeongsang National University) ;
  • Lee, Hyun-Ji (Department of Food Science and Nutrition, Institute of Agriculture and Life Science, Gyeongsang National University) ;
  • Sung, Nak-Ju (Department of Food Science and Nutrition, Institute of Agriculture and Life Science, Gyeongsang National University)
  • 조희숙 (우송대학교 외식조리학과) ;
  • 이수정 (경상대학교 식품영양학과 농업생명과학연구원) ;
  • 신정혜 (남해전문대학 호텔조리제빵과) ;
  • 강민정 (경상대학교 식품영양학과 농업생명과학연구원) ;
  • 조현소 (경상대학교 식품영양학과 농업생명과학연구원) ;
  • 이현지 (경상대학교 식품영양학과 농업생명과학연구원) ;
  • 성낙주 (경상대학교 식품영양학과 농업생명과학연구원)
  • Published : 2007.08.30
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Abstract

The composites(PM-A-PM-I) of 9 groups containing 7 kinds of hot water extracted medicinal plants were produced and evaluated its antioxidative activity. Each medicinal plants used these composites were analyzed in primer research that its anti oxidative activity was high. In the composites of medicinal plant, electron donating ability was higher than 70% in all sample. PM-D, PM-E and PM-F were significantly higher than others. Reducing power have similar tendency to electron donating ability. PM-D was the strongest in hydroxyl radical scavenging activity, followed by PM-E. In linoleic acid system, antioxidative activity of all sample was showed more than 50%, except PM-A. Especially PM-E and PM-F have significantly higher activity. Nitrite scavenging effect was significantly increased by PM-D, PM-E and PM-F added to Inula Japonica Thunberg. In these results, we suggested that high-er antioxidative activity of PM-D, PM-E and PM-F may be responsible for the contents of phenolic compounds present in Inula Japonica Thunberg. And thought to be enhanced by the synergy effect of the water extracted medicinal plants in the composite.

항산화 활성이 높은 한약재 10종을 대상으로 9종의 조성물(PM-A-PM-I)을 제조하여 항산화 활성을 비교 분석하였다. 한약재 조성물의 DPPH에 대한 전자공여능은 모든 실험군에서 70%이상이었으며, 조성물 중 PM-D, PM-E 및 PM-F가 여타 시료에 비해 유의적으로 전자공여능이 높았다. 환원력도 전자공여능과 동일한 경향이었다. Hydroxyl radical에 대한 항산화 활성은 PM-D가 가장 높았고 다음으로 PM-E였 다. Linoleic acid 에 대한 자동산화 억제능은 PM-A를 제외한 모든 시료에서 50%이상의 활성을 나타내었으며, PM-E, PM-F에서 유의적으로 활성이 높았다. 아질산염 소거능은 선복화가 첨가된 PM-D, PM-E, PM-F에서 유의적으로 높았다. 따라서 9종의한약재 조성물의 항산화활성은 첨가된 한약재의 종류가 유사하였으나 PM-D, PM-E, PM-F 에서 높은 항산화활성을 보인 것은 선복화의 작용이 컸던 것으로 생각되며, 또한 한약재에 함유된 항산화 성분간의 시너지 효과 때문인 것으로 추정된다.

Keywords

References

  1. Baranen, A. L. 1975. Toxicological and biochemistry of butylated hydroxyanisol and butylated hydroxy toluene. JAOCS 52, 59-63. https://doi.org/10.1007/BF02901825
  2. Blois, M. S. 1958. Antioxidant determination by the use of a stable free radical. Nature 26, 1199-1200.
  3. Dong, S., S. H. Jung, J. S. Moon, S. K. Rhee and J. Y. Son. 2004. Antioxidant activities of clove by extraction solvent. J. Korean Soc. Food Sci. Nutr. 33, 609-613. https://doi.org/10.3746/jkfn.2004.33.4.609
  4. Fang, Y. Z., S. Yanga and G. Wu. 2002. Free radical, antioxidant and nutrition. Nutr. 18, 872-879. https://doi.org/10.1016/S0899-9007(02)00916-4
  5. Fridorich. I. 1978. The biology of oxygen radicals. Science 201, 875-881. https://doi.org/10.1126/science.210504
  6. Gordon, M. H. 1990. The mechanism of antioxidant action in vitro. pp. 1-18. In Food Antioxidant. Hudson, B. J. F., ed. Elsevier Applied Science, London/New York.
  7. Gutteridge, J. M. 1984. Reactivity of hydroxyl and hydroxyl like radicals discriminated by release of thiobarbituric acid reactive material from deoxy sugars, nucleosides and benzoate. Biochem. J. 224, 761-767. https://doi.org/10.1042/bj2240761
  8. Hammerschmidt, P. A. and D. E. Pratt. 1978. Phenolic antioxidants of dried soybeans. J. Food Sci. 43, 556-559. https://doi.org/10.1111/j.1365-2621.1978.tb02353.x
  9. Ju, J. C., J. H. Shin, S. J. Lee, H. S. Cho and N. J. Sung. 2006. Antioxidative activity of hot water extracts from medicinal plants. J. Korean Soc. Food Sci. Nutr. 35, 7-14. https://doi.org/10.3746/jkfn.2006.35.1.007
  10. Jung, S. J., J. H. Lee, H. N. Song, N. S. Seong, S. E. Lee and N. I. Baek. 2004. Screening for antioxidant activity of plant medicinal extracts. J. Korean Soc. Appl. Biol. Chem. 47, 135-140.
  11. Kato, H., I. E. Lee, N. V. Chuyen, S. B. Kim and F. Hayase. 1987. Inhibition of nitrosamine formation by nondialyzable melanoidins. Agric. Bio. Chem. 51, 1333-1338. https://doi.org/10.1271/bbb1961.51.1333
  12. Kim, D. S., B. W. Ahn, D. M. Yeum, D. W. Lee, S. T. Kim and Y. H. Park. 1987. Degradation of carcinogenic nitrosamine formation factor by natural food components. Bull. Korean Fish. Soc. 20, 463-468.
  13. Kim, E. Y., I. H. Baik, J. H. Kim, S. R. Kim and M. R. Rhyu. 2004. Screening of the antioxidant activity of some medicinal plants. Korean J. Food Sci. Technol. 36, 333-338.
  14. Kim, J. H., B. H. Kang and J. M. Jeong. 2003. Antioxidant, antimutagenic and chemopreventive activities of a phyto-extract mixture derived from various vegetables, fruits and oriental herbs. Food Sci. Biotechnol. 12, 631-638.
  15. Kim, J. P., I. J. Chon, H. K. Cho, I. H. Ham and W. K. Whang. 2004. The antioxidant and the antidiabetic effects of ethanol extract from biofunctional foods prescriptions. Kor. J. Pharmacogn. 35, 98-103.
  16. Kim, K. D. 2004. Research of oriental medicine plant on antioxidation and ultraviolet rays absorption. J. Kor. Soc. Cosm. 10, 145-153.
  17. Kim, S. M., Y. S. Cho, E. J. Kim, M. J. Bae, J. P. Han, S. H. Lee and S. K. Sung. 1998. Effect of water extracts of Salvia miuorrhiza Ege. Primus persica Stokes, Angelica gigas Nakai and Pinus strobus on lipid oxidation. J. Korean Soc. Food Sci. Nutr. 27, 339-405.
  18. Lee, J. M. and M. S. Ahn. 1997. A study on nitrite scavenging ability of tea extracts. Korean J. Dietary Culture 12, 567-572.
  19. Lee, J. M., S. H. Lee and H. M. Kim. 2000. Use of oriental herbs as medical food. Food Industry and Nutrition 5, 50-56.
  20. Lee, S. E., N. S. Seong, J. K. Bang, C. G. Park, J. S. Seong and J. Song. 2003. Antioxidative activity of Korean medicinal plant. Korean J. Medicinal Crop. Sci. 11, 127-134.
  21. Lee, S. H., I. J. Hong, H G. Park, S. S. Jew and K. T. Kim. 2003. Functional characteristics from the barley leaves and its antioxidant mixture. - Study on the nitrite scavenging effect. J. Korean Soc. Agric. Chem. Biotechnol. 46, 333-337.
  22. Nam, S. H. and M. Y. Kang. 2000. Screening antioxidative activity of hot water extracts from medicinal plants. J. Korean Soc. Agric. Chem. Biotechnol. 43, 141-147.
  23. Oh, S. I. and M. S. Lee. 2003. Screening for antioxidative and antimutagenic capacities in seven common vegetables taken by Korean. J. Korean Soc. Food Sci. Nutr. 32, 1344-1350. https://doi.org/10.3746/jkfn.2003.32.8.1344
  24. Osawa, T. 1981. A novel type of antioxidant isolated from leaf was of Eucalyptus leaves. Agric. Biol. Chem. 45, 735-739. https://doi.org/10.1271/bbb1961.45.735
  25. Oyaizu, M. 1986. Studies on products of browning reactions: antioxidative activities of products of browning reaction prepared from glucosamine. Japanese J. Nutr. 44, 307-315. https://doi.org/10.5264/eiyogakuzashi.44.307
  26. Yang, M. S., Y. L. Ha, S. H. Nam, S. U. Choi and D. S. Jang. 1995. Screening of domestic plants with antibacterial activity. J. Korean Agric. Chem. 38, 584-589.

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