Journal of The Korean Society of Clinical Toxicology (대한임상독성학회지)

Korean society of Clincal Toxicology (대한임상독성학회)
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Treatment with the Taylor Cyanide Antidote Package after Cyanide Poisoning: Case Report

시안화물 중독 후 해독제로 치료된 2례

  • Cho, Beam-Gyu (Department of Emergency Medicine, Wonju College of Medicine, Yonsei University) ;
  • Choi, Han-Joo (Department of Emergency Medicine, Wonju College of Medicine, Yonsei University) ;
  • Jang, Yang-Soo (Department of Emergency Medicine, Wonju College of Medicine, Yonsei University) ;
  • Shin, Tae-Yang (Department of Emergency Medicine, Wonju College of Medicine, Yonsei University) ;
  • Lee, Kang-Hyun (Department of Emergency Medicine, Wonju College of Medicine, Yonsei University) ;
  • Hwang, Sung-Oh (Department of Emergency Medicine, Wonju College of Medicine, Yonsei University) ;
  • Kim, Hyun (Department of Emergency Medicine, Wonju College of Medicine, Yonsei University)
  • 조범규 (연세대학교 원주의과대학 응급의학교실) ;
  • 최한주 (연세대학교 원주의과대학 응급의학교실) ;
  • 장용수 (연세대학교 원주의과대학 응급의학교실) ;
  • 신태용 (연세대학교 원주의과대학 응급의학교실) ;
  • 이강현 (연세대학교 원주의과대학 응급의학교실) ;
  • 황성오 (연세대학교 원주의과대학 응급의학교실) ;
  • 김현 (연세대학교 원주의과대학 응급의학교실)
  • Published : 2007.06.13
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Abstract

Cyanide has been well known from antiquity. Cyanide poisoning causes histotoxic hypoxia--inhibition of mitochondrial cytochrome oxidase with disruption of the ability of cells to use oxygen. The mortality rate is 95% within 30 minutes. Acute cyanide poisoning is mostly the result of attempted suicide, and because of the high doses typically employed it usually is lethal within minutes. Also acute cyanide poisoning leads to a very poor prognosis because medical personnel can't detect cyanide intoxication and so many hospital haven't antidote. We report two cases of cyanide poisoning which responded well to treatment with the Taylor cyanide antidote package.

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