Journal of The Korean Society of Clinical Toxicology (대한임상독성학회지)

Korean society of Clincal Toxicology (대한임상독성학회)
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Epidemiology and Clinical Analysis of Poisoning of Glufosinate Herbicide - Multicenter Study -

Glufosinate 제초제 중독의 실태 조사와 임상적 특성 고찰 - 다기관 연구 -

  • Lee, Sung-Woo (Department of Emergency Medicine, Korea University College of Medicine) ;
  • Hong, Yun-Sik (Department of Emergency Medicine, Korea University College of Medicine) ;
  • Kwon, Woon-Yong (Department of Emergency Medicine, Seoul National University College of medicine) ;
  • Park, Joon-Seok (Department of Emergency Medicine, College of Medicine, Konyang University) ;
  • Eo, Eun-Kyung (Department of Emergency Medicine, School of Medicine, Ewha Womans University) ;
  • Oh, Bum-Jin (Department of Emergency Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Lee, Mi-Jin (Department of Emergency Medicine, College of Medicine, The Catholic University of Korea) ;
  • Suh, Joo-Hyun (Department of Internal Medicine, Gachon University of Medicine and Science) ;
  • Roh, Hyung-Keun (Department of Internal Medicine, Gachon University of Medicine and Science)
  • 이성우 (고려대학교 의과대학 응급의학교실) ;
  • 홍윤식 (고려대학교 의과대학 응급의학교실) ;
  • 권운용 (서울대학교 의과대학 응급의학교실) ;
  • 박준석 (건양대학교 의과대학 응급의학교실) ;
  • 어은경 (이화여자대학교 의학전문대학원 응급의학교실) ;
  • 오범진 (울산대학교 의과대학 서울아산병원 응급의학교실) ;
  • 이미진 (가톨릭대학교 의과대학 응급의학교실) ;
  • 서주현 (가천의과학대학교 내과학교실) ;
  • 노형근 (가천의과학대학교 내과학교실)
  • Published : 2007.06.13
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Abstract

Purpose: To assess the epidemiology and the clinical features of Glufosinate herbicide in Korea. Methods: Data was prospectively collected during 1 year since August 2005 from 38 hospital in Korea. We analyzed the epidemiologic characters and clinical manifestations of Glufosinate poisoning. In addition, the characteristics of patients with severe central nervous system toxicity were separately analyzed to find poor prognosis relating factors. Results: During study periods, there were 715 persons of poisoning of herbicides and insecticides. 6.3% (45 persons) of the agricultural chemicals poisoning had Glufosinate poisoning. There were 36 cases of suicide attempts and 7 cases of accidental exposure, The major of poisoning route was oral ingestion (44 cases). 28.9 % of the study patients had not toxic symptoms. The most common symptoms were gastrointestinal symptoms relating surfactant irritation. 67.7% of central nervous symptoms occurred lately. 10 persons showed severe central nervous system toxicity. 4 persons of them showed poor outcomes (1 death, 3 hopeless discharged). Complications of respiratory failure and renal failure related with poor outcome. Conclusion: Majority of patients ingested Glufosinate for suicide attempt. 22.2% of patients with Glufosinate poisoning showed delayed serious central nervous system toxicity. Early supportive care of altered mentality may prevent late respiratory complications and improve the outcomes.

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