Journal of the korean academy of Pediatric Dentistry (대한소아치과학회지)
- Volume 34 Issue 4
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- Pages.632-638
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- 2007
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- 1226-8496(pISSN)
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- 2288-3819(eISSN)
THE ANTICARIOGENIC EFFECTS OF XYLITOL ON MUTANS STREPTOCOCCI IN CHILDREN WITH MIXED DENTITION
혼합치열기 어린이에서 mutans streptococci에 대한 자일리톨 껌의 항균효과에 관한 연구
- Park, Jae-Hong (Department of Pediatric Dentistry and Institute of Oral Biology, School of Dentistry, Kyung Hee University)
- 박재홍 (경희대학교 치과대학 소아치과학교실, 구강생물학연구소)
- Published : 2007.11.30
Abstract
The purpose of this study was to investigate the effect of xylitol chewing gums on mutans streptococci (MS) counts in saliva. Sixty two children 6 to 11 years old were randomly assigned into one of three groups. Stimulated saliva specimens were plated in duplicate on conventional selective culture (mitis salivarius kanamycin bacitracin agar) for mutans streptococci. Polymerase chain reaction (PCR) amplication was performed to identify MS. After the 4-month period a significant decrease of the MS counts occurred in the group B (two gum 3 times a day; P < 0.05) but not in group A (one gum 3 times a day) and control group (didn't receive xylitol gum). According to qualitative evaluations, xylitol use did reduce the levels of MS in mixed dentition children. It has been suggested that a daily intake of 2 tablet for 3 times a day (about 10g) is needed in order to obtain a clinical anticariogenic effect.
Xylitol 껌의 mutans streptococci(MS)에 대한 항균효과를 평가하기 위하여 6세