The Korean Journal of Cytopathology (대한세포병리학회지)

The Korean Society for Cytopathology (대한세포병리학회)
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Fine Needle Aspiration Cytology of Parathyroid Neoplasms - A Review of Three Cases -

부갑상샘 종양의 세침흡인 세포소견 -3예 보고-

  • Kim, Lucia (Department of Pathology, Inha University College of Medicine) ;
  • Han, Jee-Young (Department of Pathology, Inha University College of Medicine) ;
  • Park, In-Suh (Department of Pathology, Inha University College of Medicine) ;
  • Choi, Suk-Jin (Department of Pathology, Inha University College of Medicine) ;
  • Kim, Joon-Mee (Department of Pathology, Inha University College of Medicine) ;
  • Chu, Young-Chae (Department of Pathology, Inha University College of Medicine)
  • 김루시아 (인하대학교 의과대학 병리학교실) ;
  • 한지영 (인하대학교 의과대학 병리학교실) ;
  • 박인서 (인하대학교 의과대학 병리학교실) ;
  • 최석진 (인하대학교 의과대학 병리학교실) ;
  • 김준미 (인하대학교 의과대학 병리학교실) ;
  • 주영채 (인하대학교 의과대학 병리학교실)
  • Published : 2007.03.30
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Abstract

Parathyroid tumors may be difficult to distinguish from thyroid follicular lesions, especially when a tumor is nonfunctioning. We report here two cases of asymptomatic parathyroid carcinoma preoperatively misdiagnosed as thyroid follicular lesions, and one case of parathyroid adenoma showing hyperparathyroidism, and review the cytologic features favoring the diagnosis of parathyroid neoplasm. The cytologic findings that are characterized by clean background, monomorphic small cells, cohesive three-dimensional papillary clusters, small tight clusters with scattered naked nuclei, and well-defined clear cytoplasm favor a diagnosis for the parathyroid lesions. Cytologic findings such as macrofollicular structure, presence of colloid and macrophages, and presence of perivacuolar cytoplasmic granules on May-Grunwald-Giemsa stain support a diagnosis of a thyroid follicular lesion. The cytomorphology of parathyroid tumors is so variable that the distinction from a thyroid lesion cannot be based on the presence or absence of a single feature only but on the cytologic features as a whole.

Keywords

References

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