Korean Journal of Pharmacognosy (생약학회지)

The Korean Society of Pharmacognosy (한국생약학회)
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Isolation and Quantitative Determination Method Validation of myristicin from Myristica fragrans Houttuyn

육두구(Myristica fragrans Houttuyn) 내의 myristicin의 분리 및 HPLC를 이용한 함량분석 방법 밸리데이션

  • Kim, Soo-Hwan (Analytical Science Center, Samyang Medical R&D Center) ;
  • Lee, Dong-Ho (Analytical Science Center, Samyang Medical R&D Center) ;
  • Kwon, Soo-Han (Department of Chemistry, Chungbuk National University) ;
  • Lim, Buyng-Ho (Analytical Science Center, Samyang Medical R&D Center) ;
  • Lee, Sang-Hun (Analytical Science Center, Samyang Medical R&D Center) ;
  • Min, Bum-Chan (Analytical Science Center, Samyang Medical R&D Center)
  • 김수환 (삼양사 의약연구소 분석센터) ;
  • 이동호 (삼양사 의약연구소 분석센터) ;
  • 권수한 (충북대학교 화학과) ;
  • 임병호 (삼양사 의약연구소 분석센터) ;
  • 이상훈 (삼양사 의약연구소 분석센터) ;
  • 민범찬 (삼양사 의약연구소 분석센터)
  • Published : 2007.03.31
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Abstract

Myristica fragrans has been used for the treatment of stomachache in East Asia. It is very important to determine the amount of myristicin in Myristica fragrans, because excess myristicin causes side effects. In this study, we developed and validated the method for determination contents of myristicin in Myristica fragrans which was purchased from various regions of Korea. The average content of myristicin in Myristica fragrans was 2.10% with the validated HPLC analysis method.

Keywords

References

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