한국동물위생학회지 (Korean Journal of Veterinary Service)

  • 제30권1호
  • /
  • Pages.115-123
  • /
  • 2007
  • /
  • 3022-7372(pISSN)
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  • 2287-7630(eISSN)
한국동물위생학회 (The Korean Society of Veterinary Service)
권호 표지

젖소 유방염에 대한 국내산 봉독의 치료 효과

Therapeutic effects of honeybee (Apis Mellifera L.) venom injection on bovine mastitis

  • 한상미 (농촌진흥청 농업과학기술원) ;
  • 이광길 (농촌진흥청 농업과학기술원) ;
  • 여주홍 (농촌진흥청 농업과학기술원) ;
  • 권해용 (농촌진흥청 농업과학기술원) ;
  • 우순옥 (농촌진흥청 농업과학기술원) ;
  • 오백영 (이천시 농업기술센터) ;
  • 이윤근 (이천시 농업기술센터) ;
  • 김봉순 (양평군 농업기술센터) ;
  • 백하주 (경상북도 보건환경연구원) ;
  • 김순태 (경상북도 가축위생시험소)
  • Han, Sang-Mi (National Institute of Agricultural Science and Technology) ;
  • Lee, Kwang-Gill (National Institute of Agricultural Science and Technology) ;
  • Yeo, Joo-Hong (National Institute of Agricultural Science and Technology) ;
  • Kweon, Hae-Yong (National Institute of Agricultural Science and Technology) ;
  • Woo, Soon-Ok (National Institute of Agricultural Science and Technology) ;
  • Oh, Baeg-Young (Icheon-city Agricultural Technology Service Center) ;
  • Lee, Yun-Geun (Icheon-city Agricultural Technology Service Center) ;
  • Kim, Bong-Soon (Yangpyeong Agricultural Technology Service Center) ;
  • Baek, Ha-Ju (Gyeongbuk Government Public Institute of Health and Environmental) ;
  • Kim, Soon-Tae (Northern-branch, Gyeongbuk Veterinary Service Laboratory)
  • 발행 : 2007.03.30
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초록

The therapeutic effect of honeybee venom collected using be venom collector on bovine mastitis was investigated. Mastitic cows from four farms were selected in the Yang-pyeong areas. Chronic mastitic cows were injected with the various concentrations of honey-bee venom per day. There was a significant difference in the reduction rates of somatic cell counts (SCC) according to treatment concentration and method of bee venom. The milk SCC were significantly decreased in all concentrations of bee venom 3 days after treatment. The reduction rates of SCC in treatment of 3, 6, 12 and 24mg honeybee venom were 20, 43, 63.3 and 65.8% respectively. Honeybee venom treatment consisted of two methods, a syringeful and a Bovivet Spenstift. The treatment with Bovivet Spenstift was more effective in the reduction rates of SCC compared with the syringeful. Thirty two out of 53 quarters were cured by Bovivet Spenstift with 12mg bee venom per day for 14 days. The venom cure rates of bovine mastitis by Escherichia coli, Stapylococcus aureus, Gram positive bacteria and Gram negative bacteria were 33.3, 75, 75 and 43.8% respectively. These results suggested that bee venom treatment (by Bovivet Spenstift with 12mg) might be effective for treatment of bovine mastitis.

키워드

참고문헌

  1. Komine Y, Komine KI, Kai K, et al. 2006. Effect of combination therapy with lactoferrin and antibiotics against Staphylococcal mastitis on dry in cows. J Vet Med Sci 68(3):205-211 https://doi.org/10.1292/jvms.68.205
  2. Borm AA, Fox LK, Leslie KE, et al. 2006. Effects of prepartum intra-mammary antibiotic therapy on udder health, milk production, and reproductive performance in dairy heifers. J Dairy Sci 89(6):2090-2098 https://doi.org/10.3168/jds.S0022-0302(06)72279-2
  3. Kwon HJ, Liu J, Jo SN, et al. 2005. Therapeutic effect of ozone gas on bovine mastitis. J Vet Clin 22(4) : 314-317
  4. 강의정, 김익천, 김진회 등 2001. 젖소의 유방염 원인균 분리 및 약제 감수성 검사. 대한수의학회지 41(4):511-521
  5. 문진산, 강현미, 이은실 등 2004. 젖소 유방염 유래 Staphylococcus aureus의 $\beta$-lactamase 산생과 항생제 내성 실태 조사. 대한수의공중보건학회지 29(2):121-129
  6. 문진산, 주이석, 구복경 등 1998. 젖소 유방염에 대한 키토산의 효능에 관한 연구. 대한수의학회지 38(1) : 71-76
  7. 남향미, 문진산, 주이석 등 2006. 젖소 유방염에 대한 주사용 $\beta$-carotene의 효과. 대한수의학회지 46(2) : 149-158
  8. 강현미, 문진산, 장금찬 등 2005. 가자(Terminaliae chebula) 추출물의 젖소 유방염 주요 원인체 및 메치실린내성 황색포도상구균(MRSA)에 대한 항균효과. 대한수의학회지 45(1) : 113-119
  9. 김문호. 1992. 봉독요법과 봉침요법. 한국교육기획. 서울:67-141
  10. 최석화. 2003. 꿀벌의 독을 이용한 돼지 호흡기질병의 치료 및 예방법 개발. 농림부 최종보고서. 서울
  11. 민병준, 권오석, 홍종욱 등. 2005. 생약제(Miracle) 첨가가 포유모돈의 생산성, 자돈의 성장 및 혈액성상 변화에 미치는 영향. 동물자원지 47(3):371-378 https://doi.org/10.5187/JAST.2005.47.3.371
  12. Abbadie C, Besson JM. 1994. Chronic treatments with aspirin or aceta-minophen reduce both the development of polyarthritis and Fos-like immunoreactivity in rat lumbar spinal cord. Pain 57(1):45-54 https://doi.org/10.1016/0304-3959(94)90106-6
  13. Habermann E, Reiz KG. 1965. On the biochemistry of bee venom peptides, melittin and apamin. Biochem Z 343(2):192-203
  14. Vick JA, Shipman WH. 1972. Effects of whole bee venom and its fractions (apamin and melittin) on plasma cortisol levels in the dog. Toxicon 10(4):377-380
  15. Fennell JF, Shipman WH, Cole LJ. 1967. Antibacterial action of a bee venom fraction (melittin) against a penicillin-resistant staphylococcus and other microorganisms. USNRDL-TR-67-101. Res Dev Tech Rep 5:1-13
  16. Curcio-Vonlanthen V, Schneider CH, Frutig K, et al. 1997. Molecular parameters in melittin immunogenicity. J Pept Sci 3(4):267-276 https://doi.org/10.1002/(SICI)1099-1387(199707)3:4<267::AID-PSC106>3.0.CO;2-7
  17. Rudenko SV, Nipot EE. 1996. Modulation of melittin-induced hemolysis of erythrocytes. Biokhimiia 61(12):2116-2124
  18. Cowan ST. 1974. Manual for the identification of medical bacteria. Cambridge University Press. London:45-50
  19. 조성구. 2000. 생봉독 주입에 의한 가축의 다발성질환 치료법 개발. 농림부 최종보고서. 서울
  20. 조성구, 최석화, 최향순 등. 1999. 생봉독을 이용한 돼지 관절염의 치료 효과. 한국임상수의학회지 16(1): 145-149
  21. Shkenderov S, Koburova K. 1082. Adolapin. a newly isolated analgetic and anti-inflammatory polypeptide from bee venom. Toxicon 20(1):317-321 https://doi.org/10.1016/0041-0101(82)90234-3
  22. Feng WL. 1989. Acupuncture treatment for 30 cases of infantile chronic diarrhea. J Tradit Chin Med 9(2):106-107
  23. Lin YC. 1987. Observation of therapeutic effects of acupuncture treatment in 170 cases of infantile diarrhea. J Tradit Chin Med 7(3):203-204
  24. 최석화, 강성구, 최향순 등. 1999. 생봉(Apis mellifera)을 이용한 모돈의 무유증 치료효과. 한국양봉학회지 14(2):119-126
  25. 최석화, 조성구, 최향순 등. 1999. 생봉독을 이용한 세균성 설사 자돈의 치료 효과. 한국임상수의학회지 16(1):150-154
  26. Lin JH, Rogers PAM. 1980. Acupuncture effects on the body's defense systems. Vet Bull 50:633-640
  27. Bennedsgaard TW, Enevoldsen C, Thamsborg SM, et al. 2003. Effect of mastitis treatment and somatic cell counts on milk yield in Danish organic dairy cows. J Dairy Sci 86(10):3174-3183 https://doi.org/10.3168/jds.S0022-0302(03)73920-4