Environmental Analysis Health and Toxicology

The Korean Society of Environmental Health and Toxicology (환경독성보건학회)
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Toxicity of Binary Mixture of Cyanide and 3,5-dichlorophenol to Vibrio fischeri Determined by Newly Developed $N-tox^{(R)}$ Bioassay System

국내 개발된 $N-tox^{(R)}$ 생물검정 시스템을 이용한 시안과 3, 5-이염화페놀의 발광박테리아(Vibrio fischeri)에 대한 혼합 독성 영향 연구

  • Lee, Jung-Suk (Institute of Environmental Protection and Safety, NeoEnBiz Co.) ;
  • Lee, Kyu-Tae (Institute of Environmental Protection and Safety, NeoEnBiz Co.) ;
  • Kim, Chan-Kook (Institute of Environmental Protection and Safety, NeoEnBiz Co.) ;
  • Kim, Hye-Jin (Institute of Environmental Protection and Safety, NeoEnBiz Co.) ;
  • Lee, Chang-Hoon (Institute of Environmental Protection and Safety, NeoEnBiz Co.) ;
  • Lee, Jong-Hyeon (Institute of Environmental Protection and Safety, NeoEnBiz Co.)
  • 이정석 ((주)네오엔비즈 부설환경안전연구소) ;
  • 이규태 ((주)네오엔비즈 부설환경안전연구소) ;
  • 김찬국 ((주)네오엔비즈 부설환경안전연구소) ;
  • 김혜진 ((주)네오엔비즈 부설환경안전연구소) ;
  • 이창훈 ((주)네오엔비즈 부설환경안전연구소) ;
  • 이종현 ((주)네오엔비즈 부설환경 안전연구소)
  • Published : 2007.03.31
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Abstract

Cyanides and dichlorophenols were important pollutants in industrial effluents of steel, petroleum, plastics, pesticides, synthetic dye and/or fiber manufacturing. The toxic effects of cyanide and 3, 5-dichlorophenol in the unary and binary solutions to Vibrio fischeri were determined using the newly developed $N-tox^{(R)}$ bioassay system. This bioassay system relies upon the attenuation of light intensity emitted by Vibrio fischeri exposed to various pollutants including metals and organic compounds. Most of studies dealing with toxicity of pollutants concerned single chemical species, while the organisms were typically exposed to pollutant mixtures. The present study showed that the toxicity of some binary combinations of cyanide and 3, 5-dichlorophenol significantly was lower than the predicted toxicity from the addicted model. This antagonistic interaction was well explained by chemical interaction model presented in this study.

Keywords

References

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