Clinical and Experimental Pediatrics

The Korean Pediatric Society (대한소아청소년과학회)
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Factors influencing birth weight premature infants

미숙아들의 출생 체중에 영향을 주는 요인

  • Aum, Ji A (Department of Pediatrics, Il Sin Christian Hospital) ;
  • Jung, Hee Jin (Department of Pediatrics, Il Sin Christian Hospital) ;
  • Huh, Jae Won (Department of Pediatrics, Il Sin Christian Hospital) ;
  • Hong, Su Young (Department of Pediatrics, Il Sin Christian Hospital)
  • Received : 2007.07.02
  • Accepted : 2007.08.08
  • Published : 2007.10.15
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Abstract

Purpose : The purpose of this study was to identify factors influencing premature infants who are small for their gestational ago. Methods : The medical records of 1,010 premature infants of 26 to 35 weeks of gestational age born at Il-Sin Christian Hospital, Busan from January 2000 to August 2006 were reviewed. We collected data on gestational age, birth weight, infant gender, birth order, maternal age and previous abortion history and analyzed the factors influencing premature infants who were small for their gestational ago at birth. Results : In our study more female than male (P=0.042) in premature infants who were small for their gestational ago were born from mothers aged younger than 20 or older than 35 (P=0.041). But association between smallness for gestational age and birth order or maternal previous abortion history was statistically insignificant (P=0.228, P=0.129). Conclusion : Considering the association of birth weight and the survival rate of premature infants, it is thought that maternal age had an influence on the survival rate of premature infants. Social and political support to lower the teenager pregnancy and older pregnancy is expected to increase the survival rate of premature infants and the birth of healthy normal neonates.

목 적 : 본원에서 출생한 미숙아들을 대상으로 하여 이들 미숙아들 중에서 부당 경량아 출생과 관련이 있는 요인들에 대해 알아보고자 본 연구를 시행하였다. 방 법 : 2000년 1월부터 2006년 8월까지 출생한 재태 연령 26주 이상 35주 이하의 미숙아 1,010명을 대상으로 하였으며 이들과 이들의 모체의 의무기록을 후향적으로 조사하여 재태 연령, 출생 체중, 성별, 출생 순위, 산모의 나이 및 이전 유산 횟수 등에 관한 자료들을 수집하였고 부당 경량아 출생과 관련이 있는 요인들을 비교 분석하였다. 결 과 : 본 연구에서 미숙아들 중에서 여아에서 남아보다 부당 경량아 출생이 더 많은 것으로 나타났으며(P=0.042) 또한 산모의 나이가 20세 미만이거나 35세 이상인 경우에 부당 경량아 출생이 더 많은 것으로 나타났다(P=0.041). 미숙아의 출생 순위나 산모의 이전 유산 경력은 부당 경량아 출생과 통계학적인 관련성이 없는 것으로 나타났다(P=0.228, P=0.129). 결 론 : 출생 체중과 미숙아의 생존율과의 관련성을 생각해 보면 산모의 나이가 미숙아의 생존율과 관련이 있는 것으로 생각된다. 10대 임신을 줄이고 산모가 고령이 되기 전에 출산을 할 수 있도록 여러 사회적, 정책적인 뒷받침이 이루어진다면 미숙아들의 생존율을 높이고 더 나아가 건강한 정상 신생아 분만에도 큰 도움이 되리라 생각된다.

Keywords

References

  1. Demissie K, Rhoads GG, Ananth CV, Alexander GR, Kramer MS, Kogan MD, et al. Trends in preterm birth and neonatal mortality among blacks and whites in the United States from 1989 to 1997. Am J Epidemiol 2001;154:307-15. https://doi.org/10.1093/aje/154.4.307
  2. Gonzalez R, Merialdi M, Lincetto O, Lauer J, Becerra C, Castro R, et al. Reduction in neonatal mortality in Chile between 1990 and 2000. Pediatrics 2006;117:e949-54 https://doi.org/10.1542/peds.2005-3085
  3. Tsou KI, Tsao PN. Taiwan Infant Development Collaborative Study Group. The morbidity and survival of very-lowbirth-weight infants in Taiwan. Acta Paediatr Taiwan 2003; 44:349-55
  4. Copper RL, Goldenberg RL, Creasy RK, DuBard MB, Davis RO, Entman SS, et al. A multicenter study of preterm birth weight and gestational age-specific neonatal mortality. Am J Obstet Gynecol 1993;168:78-84 https://doi.org/10.1016/S0002-9378(12)90889-3
  5. Fanaroff AA, Wright LL, Stevenson DK, Shankaran S, Donovan EF, Ehrenkranz RA, et al. Very-low-birth-weight outcomes of the National Institute of Child Health and Human Development Neonatal Research Network, May 1991 through December 1992. Am J Obstet Gynecol 1995;173: 1423-31 https://doi.org/10.1016/0002-9378(95)90628-2
  6. Lemons JA, Bauer CR, Oh W, Korones SB, Papile LA, Stoll BJ, et al. Very low birth weight outcomes of the National Institute of Child health and human development neonatal research network, January 1995 through December 1996. NICHD Neonatal Research Network. Pediatrics. 2001;107:E1 https://doi.org/10.1542/peds.107.5.e71
  7. Basso O Wilcox AJ, Weinberg CR. Birth weight and mortality: causality or confounding? Am J Epidemiol 2006;164: 303-11 https://doi.org/10.1093/aje/kwj237
  8. Larroque B, Breart G, Kaminski M, Dehan M, Andre M, Burguet A, et al. Survival of very preterm infants: Epipage, a population based cohort study. Arch Dis Child Fetal Neonatal Ed. 2004;89:F139-44 https://doi.org/10.1136/adc.2002.020396
  9. Ayoubi JM, Audibert F, Boithias C, Zupan V, Taylor S, Bosson JL, et al. Perinatal factors affecting survival and survival without disability of extreme premature infants at two years of age. Eur J Obstet Gynecol Reprod BioI 2002; 105:124-31 https://doi.org/10.1016/S0301-2115(02)00158-6
  10. Hong Chang Wee Pediatrics. 9th ed. Daehan Printing & Publishing Co, 277-8
  11. Mohsin M, Wong F, Bauman A, Bai J. Maternal and neo- natal factors influencing premature birth and low birth weight in Australia. J Biosoc Sci 2003;35:161-74 https://doi.org/10.1017/S0021932003001615
  12. Alonso V, Fuster V, Luna F. Causes of neonatal mortality in Spain (1975-98): influence of sex, rural-urban residence and age at death. J Biosoc Sci 2006;38:537-51 https://doi.org/10.1017/S0021932005026957
  13. Verloove-Vanhorick SP, Veen S, Ens-Dokkum MH, Schreuder AM, Brand R, Ruys JH. Sex difference in disability and handicap at five years of age in children born at very short gestation. Pediatrics 1994;93:576-9
  14. Italian Collaborative Group on Preterm Delivery, Bonati M. Prenatal and postnatal factors affecting short-term survival of very low birth weight infants. Eur J Pediatr 1988;147: 468-71 https://doi.org/10.1007/BF00441968
  15. Keskinoglu P, Bilgic N, Picakciefe M, Giray H, Karakus N, Gunay T. Perinatal outcomes and risk factors of Turkish adolescent mothers. J Pediatr Adolesc Gynecol 2007;20:19-24 https://doi.org/10.1016/j.jpag.2006.10.012
  16. Wasunna A, Mohammed K. Morbidity and outcome of low birthweight babies of adolescent mothers at Kenyatta National Hospital, Nairobi. East Afr Med J 2002;79:539-42
  17. Koniak-Griffin D, Turner-Pluta C. Health risks and psychosocial outcomes of early childbearing: a review of the literature. J Perinat Neonatal Nurs 2001;15:1-17
  18. Oboro VO, Dare FO. Pregnancy outcome in nulliparous women aged 35 or older. West Afr J Med 2006;25:65-8
  19. Ziadeh SM. Maternal and perinatal outcome in nulliparous women aged 35 and older. Gynecol Obstet Invest 2002;54: 6-10 https://doi.org/10.1159/000064689
  20. Machado CJ. Impact of maternal age on birth outcomes: a population-based study of primiparous Brazilian women in the city of Sao Paulo. J Biosoc Sci 2006;38:523-35 https://doi.org/10.1017/S0021932005026660
  21. Newburn-Cook CV, Onyskiw JE. Is older maternal age a risk factor for preterm birth and fetal growth restriction? A systematic review. Health Care Women Int 2005;26:852-75 https://doi.org/10.1080/07399330500230912
  22. Joseph KS, Allen AC, Dodds L, Turner LA, Scott H, Liston R. The perinatal effects of delayed childbearing. Obstet Gynecol 2005 ;105:1410-8 https://doi.org/10.1097/01.AOG.0000163256.83313.36
  23. Gao W, Paterson J, Carter S, Percival T. Risk factors for preterm and small-for-gestational-age babies: a cohort from the Pacific Islands Families Study. J Paediatr Child Health 2006;42:785-92 https://doi.org/10.1111/j.1440-1754.2006.00978.x
  24. Hirve SS, Ganatra BR. Determinants of low birth weight: a community based prospective cohort study. Indian Pediatr 1994;31:1221-5
  25. Henriet L, Kaminski M. Impact of induced abortions on subsequent pregnancy outcome: the 1995 French national perinatal survey. BJOG 2001;108:1036-42 https://doi.org/10.1016/S0306-5456(01)00243-1
  26. Pickering RM, Forbes JF. Risks of preterm delivery and small-for-gestational age infants following abortion: a population study. Br J Obstet Gynaecol 1985;92:1106-12 https://doi.org/10.1111/j.1471-0528.1985.tb03020.x
  27. Panaretto K, Lee H, Mitchell M, Larkins S, Manessis V, Buettner P, et al. Risk factors for preterm, low birth weight and small for gestational age birth in urban Aboriginal and Torres Strait Islander women in Townsville. Aust N Z J Public Health 2006;30:163-70 https://doi.org/10.1111/j.1467-842X.2006.tb00111.x