Nutritional Sciences

한국영양학회 (The Korean Nutrition Society)
권호 표지

Effects of Alcohol Intake on Body Fluid Balance and Fat Mobilization After Exercise Induced Dehydration

  • Park, Hyun-Jeong (Graduate School of Sports Industry, Kookmin University) ;
  • Bae, Yoon-Jung (Graduate School of Obesity Science, Dongduk Women's University) ;
  • Lee, Joo-Hyung (Kim Chang Kew Exercise Physiology Laboratory, Kookmin University) ;
  • Lee, Dae-Taek (Kim Chang Kew Exercise Physiology Laboratory, Kookmin University)
  • 발행 : 2006.05.01
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

To examine the effects of alcohol consumption on body fluid restoration and fat mobilization following exercise induced dehydration, nine healthy collegiate men ($24{\pm}2yrs,\;177{\pm}5cm,\;72{\pm}8kg,\;10.5{\pm}2.3%$ body fat) underwent three experiments. In each experiment, subjects ran on a treadmill to reduce individual body mass to $2.2{\pm}0.1%$ and consumed one of three beverages containing 0, 4, or 8% alcohol over 60 min followed by 4 hr of resting recovery. They consumed approximately 150% of weight loss $(2053{\pm}204,\;2091{\pm}149,\;and\;1943{\pm}295mL)$ and content of alcohol was $9.9{\pm}1.0(0%),\;71.9{\pm}5.1(4%)$, and $132.2{\pm}20.1g$ (8% trial). Body weight, urine volume and samples, blood samples, and thirst sensation were measured five times; at baseline, immediately after exercise, and 0, 1st, and 4th hr of recovery. Blood alcohol concentration after ingestion was $0.0{\pm}0.0(0%),\;0.1{\pm}0.02(4%)$, and $0.2{\pm}0.03%$ (8% trial). No differences in blood sodium and potassium concentrations, and urine specific gravity were noticed over time periods and trials. Thirst sensation tended to be elevated in all trials immediately after exercises and urine output was elevated during the recovery. The magnitude of changes in these variables was proportional to the alcohol concentrations, but not statistically significant. While serum osmolality was not different among trials and time periods in 0 and 4% trials, it was higher during recovery than the baseline in the 8% trial (P<0.01). Triglycerides did not change throughout the time period and among trials. Free fatty acids were elevated after exercise in all trials and 4th hr of recovery in 0% (P<0.05). Subjects' net body fluid balance at 4th hr of recovery was negatively maintained and proportional to alcohol concentrations. Only 8% trials showed a significant reduction at 1st and 4th hr of recovery compared to 0 hr. The results suggested that diuretic effect of alcohol after moderate level of dehydration appeared dose dependent, but beverage containing alcohol up to 4% did not induce impaired rehydration than alcohol free drinks. Alcohol effects on fat mobilization during recovery appeared to be minimal and the mechanism is unclear.

키워드

참고문헌

  1. Gonzales-Alonso J, Heaps CL, Coyle EF. Rehydration after exercise with common beverages and water. Int J Sports Med 13:399-406, 1992 https://doi.org/10.1055/s-2007-1021288
  2. Maughan RJ, Leiper JB. Sodium intake and post-exercise rehydration in man. Eur J Appl Physiol 75:311-319, 1995
  3. Maughan RJ, Leiper JB, Shirreffs SM. Factors influencing the restoration of fluid and electrolyte balance after exercise in the heat. Br J Sports Med 31:175-182, 1997 https://doi.org/10.1136/bjsm.31.3.175
  4. Nose H, Mack GW, Shi X, Nadel ER. Role of osmolality and plasma volume during rehydration in humans. J Appl Physiol 65:325-331, 1988 https://doi.org/10.1152/jappl.1988.65.1.325
  5. Mack GW, Weseman CA, Langhans GW, Scherzer H, Gillen CM, Nadel ER. Body fluid balance in dehydrated healthy older men: thirst and renal osmoregulation. J Appl Physiol 76:1615-1623, 1994 https://doi.org/10.1063/1.357741
  6. Maughan RJ, Owen JH, Shirreffs SM, Leiper SM. Post-exercise rehydration in man: effects of electolyte addition to ingested fluids. Eur J Appl Physiol 69:209-215, 1994 https://doi.org/10.1007/BF01094790
  7. Ryan AJ, Lambert GP, Shi X, Chang RT, Summers RW, Gisolfi CV. Effect of hypohydration on gastric emptying and intestinal absorption during exercise. J Appl Physiol 84:1581-1588, 1998 https://doi.org/10.1152/jappl.1998.84.5.1581
  8. Lindeman RD. Renal and urinary Thact function. In: Fregly MJ, Blatteis CM, eds. Handbook of Physiology, Aging. sect. 11, chapt.19, pp .485-504, American Physiological Society, Bethesda, MD, 1995
  9. reenleaf JE, Brock PJ, Keil LC, Morse JT. Drinking and water balance during exercise and heat acclimation. J Appl Physiol 54:414-419, 1983 https://doi.org/10.1152/jappl.1983.54.2.414
  10. Zappe DH, Bell GW, Swartzenruber H, Wideman RF, Kenny WL. Age and regulation of fluid and electrolyte balance during repeated exercise sessions. Am J Physiol 270:R71-R79, 1996
  11. Rehrer NJ. Fluid and electrolyte balance in ultra-endurance sport. Sports Med 31:701-715, 2001 https://doi.org/10.2165/00007256-200131100-00001
  12. Roberts KE. Mechanism of dehydration following alcohol ingestion. Arch Intern Med 112:154-157, 1963 https://doi.org/10.1001/archinte.1963.03860020052002
  13. Farthing MJG. Oral rehydration therapy. Pharmacol Ther 64:477-492, 1994 https://doi.org/10.1016/0163-7258(94)90020-5
  14. Eggleton MG. The diuretic action of alcohol in man. J Physiol 101: 172-191, 1942 https://doi.org/10.1113/jphysiol.1942.sp003973
  15. Kleeman CR, Rubini ME, Lamdin E, Epstein FH. Studies on alcohol diuresis. II. The evaluation of ethyl alcohol as an inhibitor of the neurohypophysis. J Clin Invest 34 :448-455, 1955 https://doi.org/10.1172/JCI103093
  16. Shirreffs SM, Maughan RJ. Restoration of fluid balance after exercise-induced dehydration: effects of alcohol consumption. J Appl Physiol 83: 1152-1158, 1997 https://doi.org/10.1152/jappl.1997.83.4.1152
  17. Crouse JR, Grundy SM. Effects of alcohol on plasma lipoproteins and cholesterol and triglyceride metabolism in men. J Lipid Res 25:486-496, 1984
  18. EI-Sayed MS, AL-Bayatti ME Effects of alcohol ingestion following exercise on postprandial lipernia. Alcohol 23:15-21, 2001 https://doi.org/10.1016/S0741-8329(00)00119-1
  19. Veenstra J, Okhuizen T, Van de Pol H, Wedel M, Schaafsma G. Effects of moderate dose of alcohol on blood lipids and lipoproteins postprandially and in the fasting state. Alcohol 25:371-377, 1990
  20. Bunout D. Nutritional and metabolic effects of alcoholism: their relationship with alcoholic liver disease. Nutrition 15:583-589, 1999 https://doi.org/10.1016/S0899-9007(99)00090-8
  21. Marmot M, Brunner E. Alcohol and cardiovascular disease: the status of V-shaped curve. Br Med J 303:565-568, 1991 https://doi.org/10.1136/bmj.303.6802.565
  22. Suter PM, Schutz Y, Jequier E. The effect of ethanol on fat storage in healthy subjects. N Engl J Med 326:983-987, 1992 https://doi.org/10.1056/NEJM199204093261503
  23. Siler SQ, Neese RA, Hellerstein MK. De novo lipogenesis, lipid kinetics, and whole-body lipid balances in humans after acute alcohol consumption. Am J Clin Nutr 70:928-936, 1999 https://doi.org/10.1093/ajcn/70.5.928
  24. Takamata A, Ito T, Yaegashi K, Takamiya H, Maegawa Y, Itoh T, Greenleaf JE, Morinloto T. Effect of an exercise-heat acclimation program on body fluid regulatory responses to dehydration in older men. Am J Physiol 277:R1041-R1050, 1999
  25. Shirreffs SM, Taylor AJ, Leiper JB, Maughan RJ. Post-exercise rehydration in man: effects of volume consumed and dodium content of ingested fluids. Med Sci Sports Exerc 28:1260-1271, 1996 https://doi.org/10.1097/00005768-199610000-00009
  26. Rubini ME, Kleeman CR, Lamdin E. Studies on alcohol diuresis. I. The effect of ethyl alcohol ingestion on water, electrolyte and acid-base metabolism. J Clin Invest 34:439-447, 1955 https://doi.org/10.1172/JCI103092
  27. Christiansen C, Thomsen C, Rasmussen O, Hauerslev C, Balle M, Hansen C, Hermansen K. Effect of alcohol on glucose, insulin, free fatty acid and triacylglycerol responses to a light meal in non-insulin-dependent diabetic subjects. Br J Nutr 71: 449-454, 1994 https://doi.org/10.1079/BJN19940151
  28. Christiansen C, Thomsen C, Rasmussen O, Hansen C, Hermansen K. The acute impact of ethanol on glucose, insulin, triacylglycerol, and free fatty acid responses and insulin sensitivity in type 2 diabetes. Br J Nutr 76:669-675, 1996 https://doi.org/10.1079/BJN19960074
  29. Rasmussen BM, Christiansen C, Rasmussen OW, Hansen C, Hermansen K. Alcohol and post-exercise metabolic responses in type 2 diabetes. Metabolism 48:597-602, 1999 https://doi.org/10.1016/S0026-0495(99)90057-4
  30. Mishra L, Le NA, Brown WV, Mezey E. Effect of acute intravenous alcohol on plasma lipoproteins in man. Metabolism 40:1128-1130, 1991 https://doi.org/10.1016/0026-0495(91)90205-B
  31. Verdy M, Gattereau A. Ethanol, lipase activity, and serum-lipid level. Am J Clin Nutr 20:997-1003, 1967 https://doi.org/10.1093/ajcn/20.9.997
  32. Nilsson-Ehle P. Alcohol-induced alterations in lipoprotein lipase activity and plasma lipoproteins. In: Avogaro P, Sirtori CR, Tremoli E, eds. Metabolic Effects of alcohol. pp.175-186, Elsevier/North-Holland Biomedical Press, Amsterdam, 1979
  33. Schneider J, Panne E, Braun H, Mordasini R, Kaffarnik H.Ethanol-induced hyperlipoproteinemia. Crucial Role preceding ethanol intake in the removal of chylomicrons. J Lab Clin Med 101:114-121, 1983
  34. Raben A, Agerholm-Larsen L, Flint A, Holst JJ, Astrup A. Meals with similar energy densities but rich in protein, fat, carbohydrate, or alcohol have different effects on energy expenditure and substrate metabolism but not on appetite and energy intake. Am J Clin Nutr 77:91-100, 2003 https://doi.org/10.1093/ajcn/77.1.91
  35. Suter PM, Jequier E, Schutz Y. Effect of ethanol on energy expenditure. Am J Physiol 266:R1204-R1212, 1994
  36. Crouse JR, Gerson CD, DeCarli LM, Lieber CS. Role of acetate in the reduction of plasma free fatty acids produced by ethanol in man. J Lipid Res 9:509-512, 1968
  37. EI-Sayed MS, Rattu AJM. Changes in lipid profile variables in response to submaximal and maximal exercise in trained cyclists. Eur J Appl Physiol 73:88-92, 1996 https://doi.org/10.1007/BF00262814