Journal of Korean Society of Occupational and Environmental Hygiene (한국산업보건학회지)

Korean Industrial Hygiene Association (한국산업보건학회)
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Validation of an Extraction Method for the Determination of Airborne MWFs using Alternative Solvents

대체용매를 이용한 금속가공유 측정방법 타당성 평가

  • Jeong, Jee Yeon (Dept. of Occupational and Environment Health, Yong-In University) ;
  • Baek, Nam Won (Department of Public Health, Seoul National University)
  • 정지연 (용인대학교 자연과학대학 산업환경보건학과) ;
  • 백남원 (서울대학교 보건대학원)
  • Received : 2006.03.14
  • Accepted : 2006.04.17
  • Published : 2006.06.30
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Abstract

The purpose of this study was to validate alternative method by using non-carcinogenic, and less toxic solvents than NIOSH analytical method 5524 for measuring the airborne MWFs in workplaces. In laboratory tests, the ETM solvents(mixture of same volume for ethyl ether, toluene, and ethanol) were selected. The alternative method of analyzing MWFs, referred to as the ETM solvent extraction method, showed 0.04 mg/sample as LOD, and 0.15 mg/sample as LOQ. The analytical precision (pooled CV, coefficient of variation) of the ETM solvent extraction method for analyzing the straight, soluble, semisynthetic, and synthetic metalworking fluid was 1.5%, 2.0%, 2.6%, 1.6%, respectively, which was similar to the precision (2.6%) of NIOSH analytical method (NIOSH 0500) for total dust. The analytical accuracy by recovery test, spiked mass calculated as extractable mass, was almost 100%. As the result of storage stability test, metalworking fluid samples should be stored in refrigerated condition, and be analyzed in two weeks after sampling. The 95% confidence limit of the estimated total standard error for the ETM solvent extraction method for analyzing the straight, soluble, semisynthetic, and synthetic metalworking fluid was ${\pm}12.6%$, ${\pm}12.5%$, ${\pm}14.0%$, and ${\pm}13.6%$, respectively, which satisfied the OSHA sampling and analytical criteria.

Keywords

References

  1. 노동부. 화학물질 및 물리적인자의 노출기준 (고시 제 2002-8호). 노동부;2002
  2. American Conference of Governmental Industrial Hygienists (ACGIH). Documentation of the threshold limit values and biological exposure indices, 7th ed. Cincinnati, OH; ACGIH; 2001
  3. American Conference of Governmental Industrial Hygienists (ACGIH). Threshold Limit Values (TLVs${\circledr}$) for Chemical Substances and Physical Agents and Biological Exposure Indices (BEIs${\circledr}$). Cincinnati, OH; ACGIH; 2005
  4. American Chemical Society(ACS) Subcommittee on Environmental Improvement. Principles of environmental analysis. Anal Chem 1983;55:2210-2218 https://doi.org/10.1021/ac00264a003
  5. American Society for Testing and Materials (ASTM). Provisional standard test method for metal removal aerosol in workplace atmosphere, Method PS 42-97. PA; ASTM;1997
  6. Burright, D., Y. Chan, M. Edie, C. Elskamp, et al. Evaluation of guidelines for air sampling methods utilizing chromatographic analysis. Salt Lake City, UT; OSHA Salt Lake Technical center; 1999
  7. Ford Motor Company. Sampling and analytical method for metalworking fluids, method No. FIH-005. Ford; 1995
  8. Glaser, R.A, S. Shulman, R. Kirimo, and G. Piacitelli. Evaluation of an ASTM method for metal working fluids in a survey of metal working facilities. J Test Eval 2002;30:439-451 https://doi.org/10.1520/JTE12335J
  9. Harper, M. Extraction metalworking fluid aerosol samples in cassettes by provisional ASTM and NIOSH methods. Am Ind Hyg Assoc J 2002;63:488-492 https://doi.org/10.1080/15428110208984738
  10. Health and Safety Executive (HSE.). Method 84, In methods for the determination of hazardous substance (MDHS). HSE; 1999
  11. Safety Executive (HSE). Method 95/2, In methods for the Health and determination of hazardous substance (MDHS). HSE;2003
  12. Intemational Agency for Research on Cancer (IARC). Dichloromethane. In monograph on the evaluation of the carcinogenic risk of chemicals to human, some halogenated hydrocarbons and pesticide exposures. Lyon, France; IARC;1986
  13. Kenyon, E.M., K. Hammond, K. Shatkin, J. Wolskie, et al. Ethanolamine exposures of workers using machining fluids in the automotive parts manufacturing industry. Appl Occup and Environ Hyg 1993;8(7):655-661 https://doi.org/10.1080/1047322X.1993.10388175
  14. Leith, D., F.A. Leith, and M.G. Boundy. Laboratory measurements of oil mist concentrations using filters and an electrostatic precipitator. Am Ind Hyg Assoc J 1996;57:1137-1141 https://doi.org/10.1080/15428119691014242
  15. National Institutes of Health (NIH). U.S. National Toxicological Program: Toxicology and carcinogenesis studies of dichloromethane (methylene chloride) in F344/rats and B6C3F1 mice (inhalation studies). Research Triangle park, NC; NIH;1986
  16. National Institute for Occupational Safety and Health (NIOSH). Guidelines for air sampling and analytical method development and evaluation [DHHS (NIOSH) Pub. No. 95-117]. Cincinnati, OH; NIOSH; 1995
  17. National Institute for Occupational Safety and Health (NIOSH). Pocket guide to chemical hazards [DHHS (NIOSH) Pub. No. 97-140]. Cincinnati, OH; NIOSH; 1997
  18. National Institute for Occupational Safety and Health (NIOSH). Method 0500, In NIOSH pocket guide to chemical hazards and other databases [DHHS (NIOSH) Pub. No.2000-130]. Cincinnati, OH; NIOSH; 2000
  19. National Institute for Occupational Safety and Health (NIOSH). Method 5524, In NIOSH manual of analytical method, 4th ed. P.M. Eller(ed.), [DHHS (NIOSH) Pub. No.2003-154]. Cincinnati, OH; NIOSH; 2003
  20. Occupational Safety and Health Administration (OSHA). Evaluation scheme for methods that use filters as the collection medium, In OSHA Analytical Methods Manual. 2nd ed. Salt Lake City, UT; OSHA Salt Lake City Analytical Laboratory;1990
  21. Occupational Safety and Health Administration (OSHA). IMIS 5010, 9135 [Online]. 2005a. Available from: http://www.osha. gov/dts/chemicalsampling/toc/toc_chemsamp.html
  22. Occupational Safety and Health Administration (OSHA). Occupational exposure to methylene chloride-68:1494-1619 [Online]. 2005b. Available from: http://www.osha.gov/dts/ oshaweb
  23. Parkinson, A. Chapter 6. Biotransformation of xenobiotics. In Casarett and Doull's Toxicology. sixth edition, New York; McGraw-Hill Companies, Inc.; 2001. pp.133-224