대한의생명과학회지 (Biomedical Science Letters)
- 제12권4호
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- Pages.427-433
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- 2006
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- 1738-3226(pISSN)
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- 2288-7415(eISSN)
Effect of Propolis on the Activity of Antioxidant Enzymes in Rat Liver Irradiated by X-ray
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서을원
(안동대학교 생명과학과)
- Lee, Ji-Hoon (Department of Biological Science, Andong National University) ;
- Ji, Tae-Jeong (Department of Radiological Science, Kaya University) ;
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Seo, Eul-Won
(Department of Biological Science, Andong National University)
- 발행 : 2006.12.31
초록
We investigated the effect of propolis on the activity of antioxidant enzymes in rat liver exposed by X-ray irradiation. The dosage of propolis showed the effect of lowering the concentration of superoxide anion in irradiated rat liver, suggesting that propolis has a significant role to remove superoxide anion as an antioxidant and/or by activating the antioxidant enzyme. The activities of superoxide dismutase (SOD) and glutathione reductase (GR), disturbed by X-ray irradiation, were restored in 30 days to normal status in the group which dosed propolis before X-ray irradiation. Interestingly, catalase (CAT) and glutathione peroxidase (GPOX) activities were highly increased with feeding propolis to rat compared to untreated group, whereas glutathione s-transferase (GST) activity was little affected. Taken together, it suggests that the propolis has a protective role in the rat liver cells against X-ray irradiation by increasing and recovering the activities of antioxidant enzymes.