Advances in Traditional Medicine

Kyung Hee Oriental Medicine Research Center (경희대학교 융합한의과학연구소)
권호 표지
DOI QR코드

DOI QR Code

Antinociceptive activity of some Bangladeshi medicinal plant extracts

  • Uddin, S.J. (Pharmacy Discipline, Life Science School, Khulna University) ;
  • Shilpi, J.A. (Pharmacy Discipline, Life Science School, Khulna University) ;
  • Rouf, R. (Pharmacy Discipline, Life Science School, Khulna University) ;
  • Ferdous, M.M. (Department of Botany, University of Rajshahi) ;
  • Nahar, L. (School of Life Sciences, The Robert Gordon University) ;
  • Sarker, S.D. (Pharmaceutical Biotechnology Research Group, School of Biomedical Sciences, University of Ulster at Coleraine)
  • Published : 2006.06.30
Download PDF
⟨ Previous Next ⟩

Abstract

The extracts of some Bangladeshi medicinal plants, Possur (Xylocarpus mekongensis), Dhundul (Xylocarpus granatum), Gab (Diospyros peregrina), Kadom (Anthocephalus chinensis) and Sundari (Heritiera fomes), were assessed for their possible antinociceptive activity using acetic acid induced writhing model in mice. Most of these plants have been used in traditional medicine in Bangladesh as well as in other countries for the treatment of various ailments ranging from common cold to cancer. All these extracts significantly inhibited the acetic acid induced writhing in mice at the oral dose of 500 mg/kg body weight. The extract of Anthocephalus chinensis bark showed the most potent writhing inhibition (69.47%, P < 0.001) and that of Diospyros peregrina bark had the least (33.54%, P< 0.02).

Keywords

References

  1. ARCBC database. (2004) ASEAN Regional Centre for Biodiversity Conservation, The Phillippines. Available on-line at: http://www.arcbc.org/arcbcweb/medicinal_plants/efault.htm.
  2. Connolly JD, MacLellan M, Okorie DA, Taylor DAH. (1976) Limonoids from Xylocarpus molucensis (Lam.) M. Roem. J. Chem. Soc. 1, 1993-1996.
  3. Chauhan JS, Kumari G. (1980) Nonadecan-7-ol-2-one an aliphatic ketol from Doiospyros peregrina. Phytochemistry 19, 2637-2638. https://doi.org/10.1016/S0031-9422(00)83935-7
  4. Conner EM and Grisham MS. (1996) Inflammation, Free radicals and antioxidants. Nutrition 12, 274-279. https://doi.org/10.1016/S0899-9007(96)00000-8
  5. Grijpma P. (1967) Anthocephalus cadama, a versatile, fast-growing industrial tree species for the tropics. Turrialba 17, 321-328.
  6. GRIN database. (2005) USDA, ARS, National Genetic Resources Program, Germplasm Resources Information Network-(GRIN), National Germplasm Resources Laboratory, Beltsville, Maryland, USA. Available on-line at: http://www.ars-grin.gov/.
  7. Ghani A. (1998) Medicinal Plants of Bangladesh. Asiatic Society of Bangladesh, Dhaka.
  8. Gupta BD, Dandiya PC, Gupta ML. (1971) A psychopharmacological analysis of behavior in rat. Jpn. J. Pharmacol. 21, 293. https://doi.org/10.1254/jjp.21.293
  9. Handa SS, Gupta SK, Vasisht K, Keene AT, Phillipson JD. (1983) Quinoline alkaloids from Anthicephalus chinensis. Planta Med. 50, 358-358. https://doi.org/10.1055/s-2007-969733
  10. Hemani T, Panihar MS. (1998) Reactive oxygen species and oxidative property of Nardostachys jatamanasi. Indian J. Expt. Biol. 34, 1150-1151.
  11. Hogg RW, Gillian FT. (1984) Fatty acids, sterols and hydrocarbons in the leaves from eleven species of mangrove. Phytochemistry 23, 93-97. https://doi.org/10.1016/0031-9422(84)83084-8
  12. Handa SS, Borris RP, Cordell GA, Phillipson JD. (1984) NMR spectral analysis of cadambine from Anthicephalus chinensis. J. Nat. Prod. 46, 325-330.
  13. Jain N, Yadav RN. (1997) Furano-(2",3",7,8)-3',5'-dimethoxy-5- hydroxyflavone: A new furanoflavone from the fruits of Diospyros peregrina Gurke. Asian J. Chem. 9, 442-444.
  14. Jain N, Yadav RN. (1994) Peregrinol, a lupane type triterpene from the fruits of Diospyros peregrina. Phytochemistry. 35, 1070-1072. https://doi.org/10.1016/S0031-9422(00)90674-5
  15. Khisal AA, Crews P, Aalbersberg B, Prasad R. (1991) Limonoids from the Fijian medicinal plant dabi (Xylocarpus granatum). Tetrahedron 47, 8943-8948. https://doi.org/10.1016/S0040-4020(01)86500-5
  16. Kirtikar KR, Basu BD. (1933) Indian Medicinal Plant, Allahabad, India.
  17. Kiritikar KR, Basu BD. (1999) Indian Medicinal Plants, 2nd edition, Allahabad, India.
  18. Kitagawa I, Wei H, Nagao S, Mahmud T, Hori K, Kobayashi M, Uji T, Shibuya H. (1996) Indonesian medicinal plants. 14. Characterisation of 3'-O-caffeoylsweroside, a new secoiridoid glucoside and kelampayosides A and B, two new phenolic Apioglucosides, from the bark of Anthocephalus chinensis (Rubiaceae). Chem. Pharm. Bull. 44, 1162-1167.
  19. Koster R, Anderson M, Beer EJ. (1959) Acetic acid for analgesic screening. Fed. Proc. 18, 412-415.
  20. Mary JM, Richard AH, Pamela CC. (1997) Lippincott's Illustrated Reviews of Pharmacology, 2nd edition, Lippincott-Raven Publishers, Philadelphia, USA.
  21. Misra PS, Misra G, Nigam SK, Mitra CR. (1971) Constituents of Diospyros peregrina fruit and seed. Phytochemistry 10, 904-905. https://doi.org/10.1016/S0031-9422(00)97175-9
  22. Parke DV, Sapota A. (1996), Chemical toxicity and reactive species. Int. J. Occup. Med. Envirn. Health 9, 119-123.
  23. Phytochemical and Ethnobotanical databases. (2005) USDA, ARS, Beltsville Agricultural Research Center, Beltsville, Maryland, USA, Available online at: http://www.ars-grin.gov/duke/.
  24. Rahman LM. (2000) The Sundarbans: A unique wilderness of the world. USDA Forest Service Proceedings RMPRS-P-15 2, 143-148.
  25. Rang HP, Dale MM. (1993) Pharmacology, pp. 706-711, 2nd edition, Churchill Livingstone publisher, UK.
  26. Singh N, Nath R, Gupta ML. (1988) A pharmacological evaluation of antistress activity of Diospyros peregrina Gurke. Indian J. Pharmacol. 20, 102-108.
  27. Shilpi SJ, Uddin SJ, Rouf R, Billah MM. (2004), Central nervous system depressant activity of Diospyros peregrina bark, Orient. Pharm. Exp. Med. 4, 249-252. https://doi.org/10.3742/OPEM.2004.4.4.249
  28. Taylor DAH. (1983) Limonoids extraction from Xylocarpus molucensis. Phytochemistry 22, 1297-1299. https://doi.org/10.1016/0031-9422(83)80251-9
  29. Tomlinson PB. (1986) The Botany of Mangroves, Cambridge University Press, New York.
  30. Uddin SJ, Shilpi JA, Alam SMS, Alamgir M, Rahman MT, Sarker SD. (2005) Antidiarrhoeal activity of the methanol extract of the barks of Xylocarpus molucensis in castor oil and magnesium sulphate-induced diarrhoea models in mice. J. Ethnopharmacol. 101, 139-143. https://doi.org/10.1016/j.jep.2005.04.006
  31. Uddin SJ, Shilpi JA, Barua J, Rouf R. (2005) Antinociceptive activity of Ceriops decandra leaf and pneumatophore, Fitoterapia 76, 261-263. https://doi.org/10.1016/j.fitote.2004.12.015
  32. Uddin SJ, Shilpi JA, Delazar A, Nahar L, Sarker SD. (2004) Free radical scavenging activity of some Bangladeshi plant extracts, Orient. Pharm. Exp. Med. 4, 185-193. https://doi.org/10.3742/OPEM.2004.4.3.187
  33. Wan-Omar A, Ibrahim J, Sulaiman O, Hashim Y. (1997) Screening of local plants for antifilarial activity against adult worm and microfilariae of Brugia pahangi. J. Tropical Forest Products 3, 216-219.
  34. Whitmore TC. (1984) A vegetation map of Malesia at scale 1-5 million. J. Biogeography 11, 461-471. https://doi.org/10.2307/2844792
  35. Winrow VR, Winyard PG, Morris CT, and Black DR. (1993) Free radicals in inflammation: Second messengers and mediators of tissue destruction. Br. Med. Bull. 49, 506-540.
  36. Wu J, Zhang S, Xiao Q, Li Q, Huang J, Long L, Huang L. (2004) Xyloccensin L, a novel limonoid from Xylocarpus granatum. Tetrahedron Lett. 45, 591-593. https://doi.org/10.1016/j.tetlet.2003.10.216
  37. Yusuf M, Chowdhury JU, Wahab MA, Begum J. (1994) Medicinal Plants of Bangladesh, Bangladesh Council of Scientific and Industrial Research, Dhaka, Bangladesh.
  38. Zaridah MZ, Idid SZ, Wan-Omar A, Khozirah S. (2001) In vitro antifilarial effects of three plant species against adult worms of subperiodic Brugia malayi. J. Ethnopharmacol. 78, 79-84. https://doi.org/10.1016/S0378-8741(01)00286-0

Cited by

  1. Leaves vol.2017, pp.1741-4288, 2017, https://doi.org/10.1155/2017/5034827