Korean Journal of Pharmacognosy (생약학회지)

The Korean Society of Pharmacognosy (한국생약학회)
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Vasorelaxation Effect of the Flavonoids from the Rhizome Extract of Alpinia offcinarum on Isolated Rat Thoracic Aorta

고량강 추출물로부터 분리된 Flavonoid 화합물의 혈압강하 효과

  • Published : 2006.03.30
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Abstract

The vascular relaxant effets of Alpinia officinarum(Zingiberaceae) were evaluated on isolated thoracic aorta from rats. The methanolic extract of rhizome of Alpinia officinarum caused a concentration-dependent relaxation of rat aortic preparations precontracted with $0.3{\mu}M$ phenylephrine, The intensive investigation of the extract by way of activity-guided fractionation led us to yield three kind of active components, galangin(1), kaempferide(2), and kaempferol(3), which were responsible for the vasodilating property of the extract. Stuctures of the isolated active components were established by chemical and spectroscopic means.

Keywords

References

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