Effect of Bojungikgitang on Starvation Stress in Mice

보중익기탕(補中益氣湯)이 생쥐의 기아(飢餓)stress에 미치는 영향

  • Kim, Jung-Hoon (Dept. of Formulae Pharmacology, School of Oriental Medicine, Kyungwon University) ;
  • Lee, Tae-Hee (Dept. of Formulae Pharmacology, School of Oriental Medicine, Kyungwon University)
  • 김정훈 (경원대학교 한의과대학 방제학교실) ;
  • 이태희 (경원대학교 한의과대학 방제학교실)
  • Published : 2006.06.30

Abstract

Objectives: We investigated the effect of Bojungikgitang on the change of the corticosterone and the rectal temperature of the mice induced by starvation stress. Methods: After administration of Bojungikgitang three times, mice were starved. The corticosterone and rectal temperature were measured after 36.5 hours starvation stress. Results : The plasma corticosterone level in Bojungikgitang(0.25g/Kg) was decreased comparing with the Control group and the rectal temperature in the Bojungikgitang(1.0g/Kg) was increased comparing with the Control group. Conclusion : it might be recognized that Bojungikgitang has anti starvation stress effect, and also it might be needed further study in various viewpoints.

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