Herbal Formula Science (대한한의학방제학회지)

The Korean Medicine Society for the Herbal Formula Study (대한한의학방제학회)
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Effect of Cheunggansoyosan-gamibang on Hyperlipidemic mice

청간소요산가미방(淸肝逍遙散加味方)이 생쥐의 고지혈증에 미치는 영향

  • Baek, Yong-Ju (Department of Internal Medicine, College of Oriental Medicine, Dong-Shin University) ;
  • Yang, Seung-Jung (Sun Cheon Oriental Medicine Hospital, Dong-Shin University) ;
  • Park, Hye-Sun (Sun Cheon Oriental Medicine Hospital, Dong-Shin University) ;
  • Kim, Kyoung-Su (Department of Radiology, College of Oriental Medicine, Dong-Shin University) ;
  • Hong, Seok (Department of Internal Medicine, College of Oriental Medicine, Dong-Shin University) ;
  • Jeon, Sang-Yoon (Department of Internal Medicine, College of Oriental Medicine, Dong-Shin University)
  • 백용주 (동신대학교 한의과대학 내과학교실) ;
  • 양승정 (동신대학교 순천한방병원) ;
  • 박혜선 (동신대학교 순천한방병원) ;
  • 김경수 (동신대학교 한의과대학 방사선과교실) ;
  • 홍석 (동신대학교 한의과대학 내과학교실) ;
  • 전상윤 (동신대학교 한의과대학 내과학교실)
  • Published : 2006.06.30
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Abstract

Hyperlipidemia is one of dangerous factors causing the arteriosclerosis. For the study of Cheunggansoyosan-gamibang( CGSYS) on antihyperlipidemic effect, we had fed mice divided to three groups (basal diet, hyperlipidemic diet, hyperlipidemic diet + CGSYS), and observed the change of weight, total cholesterol. triglyceride, HDL-cholesterol. LDL-cholesterol. sGOT, sGPT on the serum per every 7days for 6weeks. Also to compensate for the results above, we had tested rat liver. The results of this Study were obtained as fallows ; 1. Cholesterol change on blood was decreased by CGSYS. 2. Total cholesterol. triglyceride and LDL-cholesterol were significantly decreased by CGSYS. 3. HDL-cholesterol was significantly increasd by CGSYS. 4. sGPT was significantly decreased by CGSYS. 5. sGOT was not changed by CGSYS. 6. In case of supplying CGSYS. fatty degeneration was not observed in liver portal area. This study suggests that Cheunggansoyosan-gamibang was significant effect with hyperlipidemia.

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