YAKHAK HOEJI (약학회지)

The Pharmaceutical Society of Korea (대한약학회)
권호 표지

The Study of MLS-Resistant Gram Positive Cocci Isolated In a Korean Hospital

임상 분리 그람 양성 구균에 대한 MLS계 항생물질의 내성

  • Yoon, Eun-Jeong (College of Pharmacy and Reserach Institute of Pharmaceutical Sciences, Seoul National University) ;
  • Yoon, Jong-Min (College of Pharmacy and Reserach Institute of Pharmaceutical Sciences, Seoul National University) ;
  • Choi, Sung-Sook (Department of Pharmacy, Sahmyook University) ;
  • Kwon, Ae-Ran (College of Pharmacy and Reserach Institute of Pharmaceutical Sciences, Seoul National University) ;
  • Shim, Mi-Ja (Department of Life Science, University of Seoul) ;
  • Choi, Eung-Chil (College of Pharmacy and Reserach Institute of Pharmaceutical Sciences, Seoul National University)
  • 윤은정 (서울대학교 약학대학.종합 약학 연구소) ;
  • 윤종민 (서울대학교 약학대학.종합 약학 연구소) ;
  • 최성숙 (삼육대학교 약학과) ;
  • 권애란 (서울대학교 약학대학.종합 약학 연구소) ;
  • 심미자 (서울시립대학교 생명과학과) ;
  • 최응칠 (서울대학교 약학대학.종합 약학 연구소)
  • Published : 2006.06.30
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Abstract

A total of 398 strains of Staphylococcus aureus (99), coagulase-negative staphylococci (CNS) (99), enterococci (100), Streptococcus pyogenes (18) and Streptococcus agalatiae (82) were in Korean tertiary hospital from Dec. 2004 to Mar, 2005. When minimal inhibitory concentrations (MIC), phenotypes and genotypes were determined, 70% of S. aureus, 65.7% of CNS, 78% of enterococci and 37.8% of S. agalatiae were resistant to erythromycin and 95.7% of erythromycin-resistant (EMR) S. aureus, 92.3% of EMR CNS and all of EMR enterococci and S. agalatiae had erm of the methylase gene or msr(A) of the efflux gene.

Keywords

References

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