A Case of Extramedullary Plasmacytoma in Palatine Tonsil Achieved Complete Remission by Radiotherapy

국소 방사선 치료에 완전 관해된 구개편도에 발생한 골수외 형질세포종

  • Lee Jung-Hwa (Department of Internal Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine) ;
  • Kim Ki-Seong (Department of Internal Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine) ;
  • Kim Hyo-Jung (Department of Internal Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine) ;
  • Park Hee-Chul (Department of Radiation Oncology, Hallym University Sacred Heart Hospital, Hallym University College of Medicine) ;
  • Bae Hoon-Sik (Department of Radiation Oncology, Hallym University Sacred Heart Hospital, Hallym University College of Medicine) ;
  • Ha Jun-Wook (Department of Internal Medicine, Hyewon St. Marry's Hospital) ;
  • Zang Dae-Young (Department of Internal Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine)
  • 이정화 (한림대학교 의과대학 한림대학교 성심병원 내과학교실) ;
  • 김기성 (한림대학교 의과대학 한림대학교 성심병원 내과학교실) ;
  • 김효정 (한림대학교 의과대학 한림대학교 성심병원 내과학교실) ;
  • 박희철 (한림대학교 의과대학 한림대학교 성심병원 방사선종양학교실) ;
  • 배훈식 (한림대학교 의과대학 한림대학교 성심병원 방사선종양학교실) ;
  • 하준욱 (혜원성모병원 내과) ;
  • 장대영 (한림대학교 의과대학 한림대학교 성심병원 내과학교실)
  • Published : 2005.11.01

Abstract

Extramedullary plasmacytoma(EMP) is a rare tumor that originates as a clone of malignant transformed plasma cells. EMPs make up 4% of all plasma cell tumors and 90% of EMP cases occur in the head and neck area. The diagnosis of EMP is based on the morphologic and immunophenotypical finding of a localized collection of monoclonal plasma cells in the absence of plasma cell proliferation elsewhere. Patients with EMP can be treated by surgery or radiotherapy alone or in combination. EMP has good prognosis but long-term follow-up is critical because local recurrence or systemic progression to multiple myeloma may develop more than 30 years after the initial diagnosis of EMP. We report a case of EMP in palatine tonsil of 21-year old man who was treated successfully by radiotherapy alone.

골수외 형질세포종은 드문 종양으로 두경부에 주로 발생하며 수술 혹은 방사선의 국소 치료로 완치가 가능한 종양이다. 저자들은 구개편도에 발생 후 국소 방사선 치료로 완전 관해된 골수외 형질세포종 1예를 경험하였기에 보고하는 바이다.

Keywords

References

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