시력 저하를 주소로 내원한 세기관지폐포암 1예

A Case of Bronchioloalveolar Carcinoma Presenting with Initial Symptom of Visual Disturbance due to Intraocular Metastasis

  • 박선영 (연세대학교 의과대학 내과학교실) ;
  • 오형중 (연세대학교 의과대학 내과학교실) ;
  • 문진욱 (연세대학교 의과대학 내과학교실) ;
  • 강신명 (연세대학교 의과대학 내과학교실) ;
  • 한창훈 (연세대학교 의과대학 내과학교실) ;
  • 박무석 (연세대학교 의과대학 내과학교실) ;
  • 김영삼 (연세대학교 의과대학 내과학교실) ;
  • 장준 (연세대학교 의과대학 내과학교실) ;
  • 김성규 (연세대학교 의과대학 내과학교실) ;
  • 조상호 (연세대학교 의과대학 병리학교실) ;
  • 김세규 (연세대학교 의과대학 내과학교실)
  • Park, Sun Young (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Oh, Hyung Jung (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Moon, Jin Wook (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Kang, Shin Myung (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Hahn, Chang Hoon (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Park, Moo Suk (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Kim, Young Sam (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Chang, Joon (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Kim, Sung Kyu (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Cho, Sang Ho (Department of Pathology, Yonsei University College of Medicine) ;
  • Kim, Se Kyu (Department of Internal Medicine, Yonsei University College of Medicine)
  • 투고 : 2005.04.04
  • 심사 : 2005.06.23
  • 발행 : 2005.07.30

초록

저자들은 좌안의 시력 저하를 주소로 내원한 52세의 남자 환자에서 안구를 비롯한 간과 뇌 등에 전이성 병변을 동반한 세기관지폐포암 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

Intraocular tumors are uncommon and an intraocular metastatic carcinoma is extremely rare. An intraocular metastasis in adults most often originates from the breast or the lung. An intraocular lesion may be the first presentation of cancer and a search should be made to locate the primary tumor. To our knowledge, an intraocular metastasis of a bronchioloaveolar carcinoma has not reported in Korea. We report a case of a bronchioloalveolar carcinoma presenting with the initial symptom of a unilateral visual disturbance due to an intraocular metastasis.

키워드

참고문헌

  1. Divine RD, Anderson RL. Metastatic small cell carcinoma masquerading as orbital myositis. Ophthalmic Surg 1982;13:483-7
  2. Velten IM, Gusek-Schneider GC, Tomandl B. Diplopia as first symptom of a bronchogenic carcinoma. Klin Monatsbl Augenheilkd 2000;217:52-4 https://doi.org/10.1055/s-2000-10383
  3. Nelson CC, Hertzberg BS, Klintworth GK. A histopathologic study of 716 unselected eyes in patients with cancer at the time of death. Am J Ophthalmol 1983;95:788-93
  4. Ferry AP, Font RL. Carcinoma metastatic to the eye and orbit: a clinicopathologic study of 227 cases. Arch Ophthalmol 1974;92:276-86 https://doi.org/10.1001/archopht.1974.01010010286003
  5. Shields JA, Shileds CL. Metastatic tumors to the intraocular structures. In: Shields JA, Shields CL, editors. Intraocular tumors: a text and atlas. Philadelphia: W B Saunders Co; 1992. p. 207-38
  6. Matsuda H, Chida K, Hashimoto D, Naito T, Fujisawa T, Enomoto N, et al. A case of adenocarcinoma of the lung presenting symptoms of choroidal metastasis as the initial clinical manifestation. Nihon Kokyuki Gakkai Zasshi 2004;42:410-4
  7. Perl M. Contributions to pathology of tumors. Virchows Arch A 1872;56:437-67 https://doi.org/10.1007/BF01973432
  8. Song MJ, Joo DW, Park BI. A case of metastatic squamous cell carcinoma of choroids. J Korean Ophthalmol Soc 1991;32:546-9
  9. Jung KJ, Kim TH, Koh HJ, Byun YJ. A case of choroidal metastasis of pancreatic carcinoma. J Korean Ophthalmol Soc 1999;40:1155-9
  10. Lee MS, Chung SM, Baek NH. A case of papillary adenocarcinoma metastasized to both eyes. J Korean Ophthalmol Soc 1990;31:825-9
  11. Patel AM, Peters SG. Clinical manifestations of lung cancer. Mayo Clin Proc 1993;68:273-7
  12. Kreusel KM, Wiegel T, Stange M, Bornfeld N, Hinkelbein W, Foerster MH. Choroidal metastasis in disseminated lung cancer: frequency and risk factors. Am J Ophthalmol 2002;134:445-7 https://doi.org/10.1016/S0002-9394(02)01580-5
  13. Morgan WE 3rd, Malmgren RA, Albert DM. Metastatic carcinoma of the ciliary body simulating uveitis: diagnosis by cytologic examination of aqueous humor. Arch Ophthalmol 1970;83:54-8 https://doi.org/10.1001/archopht.1970.00990030056010
  14. Sierocki JS, Charles NC, Schafrank M, Wittes RE. Carcinoma metastatic to the anterior ocular segment: response to chemotherapy. Cancer 1980;45:2521-3 https://doi.org/10.1002/1097-0142(19800515)45:10<2521::AID-CNCR2820451009>3.0.CO;2-5
  15. Maor M, Chan RC, Young SE. Radiotherapy of choroidal metastases: breast cancer as primary site. Cancer 1977;40;2081-6 https://doi.org/10.1002/1097-0142(197711)40:5<2081::AID-CNCR2820400515>3.0.CO;2-O