Tuberculosis and Respiratory Diseases

  • 제59권2호
  • /
  • Pages.198-203
  • /
  • 2005
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  • 1738-3536(pISSN)
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  • 2005-6184(eISSN)
대한결핵및호흡기학회 (The Korean Academy of Tuberculosis and Respiratory Diseases)
권호 표지

폐암과 위암을 동반한 말단비대증 1예

A Case of Acromegaly Associated with Lung and Gastric Cancer

  • 김진수 (가톨릭대학교 의과대학 내과학교실) ;
  • 길욱현 (가톨릭대학교 의과대학 내과학교실) ;
  • 송도선 (가톨릭대학교 의과대학 내과학교실) ;
  • 양홍준 (가톨릭대학교 의과대학 내과학교실) ;
  • 이혁 (가톨릭대학교 의과대학 내과학교실) ;
  • 허민 (가톨릭대학교 의과대학 내과학교실) ;
  • 김정표 (가톨릭대학교 의과대학 내과학교실) ;
  • 권순석 (가톨릭대학교 의과대학 내과학교실) ;
  • 김영균 (가톨릭대학교 의과대학 내과학교실) ;
  • 김관형 (가톨릭대학교 의과대학 내과학교실) ;
  • 문화식 (가톨릭대학교 의과대학 내과학교실) ;
  • 송정섭 (가톨릭대학교 의과대학 내과학교실) ;
  • 박성학 (가톨릭대학교 의과대학 내과학교실) ;
  • 안중현 (가톨릭대학교 의과대학 내과학교실)
  • Kim, Jin Soo (Department of Internal Medicine, The Catholic University of Korea College of Medicine) ;
  • Kil, Uk Hyun (Department of Internal Medicine, The Catholic University of Korea College of Medicine) ;
  • Song, Do Seon (Department of Internal Medicine, The Catholic University of Korea College of Medicine) ;
  • Yang, Hong Jun (Department of Internal Medicine, The Catholic University of Korea College of Medicine) ;
  • Lee, Hyeug (Department of Internal Medicine, The Catholic University of Korea College of Medicine) ;
  • Huh, Min (Department of Internal Medicine, The Catholic University of Korea College of Medicine) ;
  • Kim, Jeong Pyo (Department of Internal Medicine, The Catholic University of Korea College of Medicine) ;
  • Kwon, Soon Seog (Department of Internal Medicine, The Catholic University of Korea College of Medicine) ;
  • Kim, Young Kyoon (Department of Internal Medicine, The Catholic University of Korea College of Medicine) ;
  • Kim, Kwan Hyoung (Department of Internal Medicine, The Catholic University of Korea College of Medicine) ;
  • Moon, Hwa Sik (Department of Internal Medicine, The Catholic University of Korea College of Medicine) ;
  • Song, Jeong Sup (Department of Internal Medicine, The Catholic University of Korea College of Medicine) ;
  • Park, Sung Hak (Department of Internal Medicine, The Catholic University of Korea College of Medicine) ;
  • Ahn, Joong Hyun (Department of Internal Medicine, The Catholic University of Korea College of Medicine)
  • 투고 : 2005.04.27
  • 심사 : 2005.07.21
  • 발행 : 2005.08.30
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초록

드물게 발생하는 말단비대증은 성장호르몬 및 IGF-1의 증가에 따라 악성 및 양성 종양의 발생이 증가하는 것으로 알려지고 있어 이에 대한 조기 발견과 치료에 노력을 기울여야 할 것이다. 저자들은 58세 남자가 객혈을 주소로 내원하여 폐의 편평 상피 세포암과 위선암 및 대장 폴립이 동반된 말단비대증 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

Patients with acromegaly have high incidence of benign or malignant neoplasia than general population. Around fifteen percent of the deaths reported in acromegaly are attributable to malignancy of cancer. On the whole, mortality in acromegaly has been shown to be correlated with the degree of growth hormone (GH) control. Especially, the levels of insulin like growth factor-1 (IGF-1) may be higher in neoplasm, but there is no clear evidence to prove that tumor development is triggered by IGF-1 in acromegaly. Henceforth, we report a case of acromegaly associated with lung and gastric cancer in a 58-year-old man, suggesting the possible carcinogenic role of IGF-1.

키워드

참고문헌

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