Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
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A Case of Poorly Differentiated Squamous Cell Lung Cancer with Hyperamylasemia

아밀라제 상승이 동반된 저분화 편평상피세포폐암 1예

  • Chung, Hyun Soo (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Park, Moo Suk (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Kim, Young Sam (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Kim, Se Kyu (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Chang, Joon (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Kim, Sung Kyu (Department of Internal Medicine, Yonsei University College of Medicine)
  • 정현수 (연세대학교 의과대학 내과학교실) ;
  • 박무석 (연세대학교 의과대학 내과학교실) ;
  • 김영삼 (연세대학교 의과대학 내과학교실) ;
  • 김세규 (연세대학교 의과대학 내과학교실) ;
  • 장준 (연세대학교 의과대학 내과학교실) ;
  • 김성규 (연세대학교 의과대학 내과학교실)
  • Received : 2005.10.27
  • Accepted : 2005.11.07
  • Published : 2005.12.30
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Abstract

A 78-year-old man was admitted to our hospital as a result of dyspepsia with a 2-month duration. Upon admission, the laboratory data showed a marked elevation in amylase activity in both the serum and urine. The pancreas and salivary glands were considered unlikely to have any clinical involvement in the hyperamylasemia. The chest PA revealed a right side pleural effusion, and the chest CT showed a heterogeneous enhancing mass on the subcarinal area. The patient was diagnosed bronchoscopically with a poorly differentiated squamous cell carcinoma. The amylase isoenzyme patterns indicated the salivary types, but lung cancer was strongly suspected to be the source. In most cases, lung cancers with hyperamylasemia have been diagnosed as adenocarcinomas. A squamous cell carcinoma is quite rare. We report an interesting case of squamous cell lung cancer with hyperamylasemia.

원발성 폐암에서 아밀라제가 증가하는 기전은 정확히 밝혀져 있지 않으나 대부분 타액형이며, 조직학적으로 거의 대부분이 선암이었으며, 일부 소세포폐암에서 부종양증후군으로 고아밀라제 혈증을 동반한 경우가 보고되고 있으나, 편평상피세포 폐암과 동반된 예는 국내에서 보고된 바가 없어 이를 문헌고찰과 함께 보고하는 바이다.

Keywords

References

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