대한의용생체공학회:의공학회지 (Journal of Biomedical Engineering Research)

  • 제26권1호
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  • Pages.43-47
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  • 2005
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  • 1229-0807(pISSN)
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  • 2288-9396(eISSN)
대한의용생체공학회 (The Korean Society of Medical and Biological Engineering)
권호 표지

Development of a Small Animal CT using a Linear Detector Array and Small-Scale Slip Rings

  • An Ung Hwan (Dept. of Biomedical Engineering, Kyung Hee University) ;
  • Chun In Kon (Dept. of Biomedical Engineering, Kyung Hee University) ;
  • Lee Sang Chul (Dept. of Biomedical Engineering, Kyung Hee University) ;
  • Cho Min Hyoung (Dept. of Biomedical Engineering, Kyung Hee University) ;
  • Lee Soo Yeol (Dept. of Biomedical Engineering, Kyung Hee University)
  • 발행 : 2005.02.01
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초록

We have developed a small bore x-ray CT for small animal imaging with a linear x-ray detector array and small-scale slip rings. The linear x-ray detector array consists of 1024 elements of 400□m×400□m with a gadolinium oxysulfide (GOS) scintillator on top of them. To avoid use of expensive large diameter slip rings for projection data transmission from the X­ray detector to the image reconstruction system, we used the wireless LAN technology. The projection data are temporally stored in the data acquisition system residing on the rotating gantry during the scan and they are transmitted to the image reconstruction system after the scan. With the wireless LAN technology, we only needed to use small-scale slip rings to deliver the AC electric power to the X-ray generator and the power supply on the rotating gantry. The performances of the small animal CT system, such as SNR, contrast, and spatial resolution, have been evaluated through experiments using various phantoms. It has been experimentally found that the SNR is almost linearly proportional to the tube current and tube voltage, and the minimum resolvable contrast is less than 30 CT numbers at 40kVp/3.0㎃. The spatial resolution of the small animal CT system has been found to be about 0.9Ip/㎜. Postmortem images of a piglet is also presented.

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참고문헌

  1. Michael J. Paulus, Shaun S. Gleason, M. Evangeline Easterly, and Charmaine J. Foltz, 'A Review of High-Resolution X-ray Computed Tomography and Other Imaging Modalities for Small Animal Research', Lab Animal, Vol. 30, No.3, pp. 36-45, 2001
  2. Cherry S.R, Shao Y., Silverman RW., Meadors K., Siegel S., Chatziioannou A., Young J.W., Jones W., Moyers J.C., Newport D., Boutefnouchet A., Farquhar T.H., Andreaco M., Paulus M.J., Binkley D.M., Nutt R., and Phelps M.E., 'MicroPET: A High Resolution PET scanner for Imaging Small Animals', IEEE Trans. Nucl. Sci., Vol. 44, No.3, pp. 1161-1166, 1997 https://doi.org/10.1109/23.596981
  3. David P. McElroy, Lawrence R MacDonald, Freek J. Beekman, Yuchuan Wang, Bradley E. Patt, Jan S. Iwanczyk, Benjamin M. W. Tsui, and Edward J. Hoffman, 'Performance Evaluation of A-SPECT: A High Resolution Desktop Pinhole SPECT System for Imaging Small Animals', IEEE Trans. Nucl. Sci., Vol. 49, No.5, pp. 2139-2147, 2002 https://doi.org/10.1109/TNS.2002.803801
  4. Masaya Takahashi, David B. Hackney, Guixin Zhang, Suzanne L. Wehrli, Alex C. Wright, William T. O'Brien, Hidemasa Uematsu, Felix W. Wehrli, and Michael E. Selzer, 'Magnetic resonance microimaging of intraaxonal water diffusion in live excised lamprey spinal cord', Proc. Natl. Acad. Sci., Vol. 99, No. 25, pp. 16192-16196, 2002
  5. S. C. Lee, M. H. Cho, and S. Y. Lee, 'Performance Comparison of Reconstruction Algorithms for Fan-Beam Computerized Tomography', J. Biomed. Eng. Res., Vol. 22, No.3, pp. 223-229, 2001
  6. G. N. Ramachandran, and A. V. Lakshminarayanan, 'Three dimensional reconstructions from radiographs and electron micrographs: application of convolution instead of Fourier transforms', Proc. Natl. Acad. Sci., Vol. 68, pp. 2236-2240, 1971
  7. Ed. S. Webb, The Physics of Medical Imaging, Inst. of Phys. Pub., pp. 123-131, 1988
  8. Holdsworth D W, Drangova M, Fenster A, 'A high-resolution XRII-based quantitative volume CT scanner', Med. Phys., Vol. 20, No.2, pp. 449-462, 1993 https://doi.org/10.1118/1.597038
  9. Jiang Hsieh, Computed Tomography: Principles, Design, Artifacts, and Recent Advances, Bellingham: SPIE Press, pp. 265-276, 2003
  10. C. H. McCollough, F. E. Zink, Performance evaluation of CT systems, Categorical Courses in Diagnostic Radiology Physics, pp. 189-207, 2000