Journal of Biomedical Engineering Research (대한의용생체공학회:의공학회지)

The Korean Society of Medical and Biological Engineering (대한의용생체공학회)
권호 표지

Zoom-in X-ray Micro Tomography System

  • Chun, In-Kon (Department of Biomedical Engineering, Kyung Hee University) ;
  • Lee, Sang-Chul (Department of Biomedical Engineering, Kyung Hee University) ;
  • Park, Jeong-Jin (Department of Biomedical Engineering, Kyung Hee University) ;
  • Cho, Min-Hyoung (Department of Biomedical Engineering, Kyung Hee University) ;
  • Lee, Soo-Yeol (Department of Biomedical Engineering, Kyung Hee University)
  • Published : 2005.10.01
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Abstract

We introduce an x-ray micro tomography system capable of high resolution imaging of a local region inside a small animal. By combining two kinds of projection data, one from a full field-of-view (FOV) scan of the whole body and the other from a limited FOV scan of the region of interest, we have obtained zoomed-in images of the region of interest without any contrast a nomalies. We have integrated a micro tomography system using a micro-focus x-ray source, a $1248\times1248$ flat-panel x-ray detector, and a precision scan mechanism. Using the cross-sectional images taken with the zoom-in micro tomography system, we measured trabecular thicknesses of femur bones in postmortem rats. To compensate the limited spatial resolution in the zoom-in micro tomography images, we used the fuzzy distance transform for the calculation of the trabecular thickness. To validate the trabecular thickness measurement with the zoom-in micro tomography images, we compared the measurement results with the ones obtained from the conventional micro tomography images of the extracted bone samples.

Keywords

References

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