Maxillofacial Plastic and Reconstructive Surgery

Korean Association of Maxillofacial Plastic and Reconstructive Surgeons (대한악안면성형재건외과학회)
권호 표지

STUDY ON PLATELET RICH PLASMA CONCENTRATION ACCORDING TO PROCESSING METHOD

처리방법에 따른 혈소판 혈장의 농축도에 관한 연구

  • Min, Seung-Ki (Dept. of Oral & Maxillofacial Surgery, School of Dentistry, Wonkwang University) ;
  • Kim, Hyung-Ju (Dept. of Oral & Maxillofacial Surgery, School of Dentistry, Wonkwang University) ;
  • Cha, Soo-Ryen (Dept. of Oral & Maxillofacial Surgery, School of Dentistry, Wonkwang University)
  • 민승기 (원광대학교 치과대학 구강악안면외과학교실) ;
  • 김형주 (원광대학교 치과대학 구강악안면외과학교실) ;
  • 차수련 (원광대학교 치과대학 구강악안면외과학교실)
  • Published : 2005.01.31
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Abstract

Recently, Platelet rich plasma(PRP) is commonly used because it is now well known that platelets have many functions beyond that of simple hemostasis in aspect of containing autogenous source of several growth factors. It could be responsible for increasing cell mitosis, increasing collagen production, recruiting other cells to the site of injury, initiating vascular ingrowth, and inducing cell differentiation, enhancing bone formation capacity and easily handling to clinician. However, in spite of these clinical advantages, still the theory behind the use of PRP is compelling. This study was to determine preparation techniques used to increase the concentration of platelets and growth factors are all crucial steps in early wound healing of bone graft which may lead to a more rapid and denser bone regenerate. 200 volunteers were sampled and PRP were prepared according to each evaluation item in this study. Higher concentration of platelets have been gained in double centrifugation. 2000 and 2500 rpm showed proper concentration of platelets at first centrifugation and 5000 rpm in second. Timing for 2 minutes was showed good concentration of platelets in high and low centrifugation speed. It was better concentration of platelets in 20 or 30 ml volume during centrifugation. In histomorphologic findings, degrnulated and high concentraion of platelets were found in low centrifugation speed.

Keywords

References

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