A Case of Necrotizing Meningoencephalitis in a Maltese Dog

말티즈견에서 괴사성 뇌막뇌염 증례

  • Park Jin-hee (College of Veterinary Medicine, Kyungpook National University) ;
  • Eom Ki-dong (College of Veterinary Medicine, Kyungpook National University) ;
  • Kim Jae-hoon (Department of Veterinary Medicine, Jeju National University) ;
  • Seong Yun-sang (College of Veterinary Medicine, Kyungpook National University) ;
  • Lee Hae-oon (College of Veterinary Medicine, Kyungpook National University) ;
  • Lee Sang-gwan (College of Veterinary Medicine, Kyungpook National University) ;
  • Jang Kwang-ho (College of Veterinary Medicine, Kyungpook National University) ;
  • Lee Keun-woo (College of Veterinary Medicine, Kyungpook National University) ;
  • Kweon Oh-deog (College of Veterinary Medicine, Kyungpook National University) ;
  • Park Hyun-jung (Department of Veterinary Medicine, Jeju National University) ;
  • Oh Tae-ho (College of Veterinary Medicine, Kyungpook National University)
  • Published : 2005.09.01

Abstract

A 18-month-old, male Maltese dog with acute seizure was referred to Veterinary Medical Teaching Hospital, Kyungpook National University. Abnormal neurologic findings included a tendency to fall to the left, turn and circle to the right, negative bilateral menace responses and pupillary light reflexes, and diminished responses to facial sensation testing on both sides. Radiographic signs were normal, except for occipital dysplasia. Magnetic resonance imaging of the brain revealed bilateral asymmetric ventriculomegaly, which is more on left side. Cerebral edema was also suspected. The dog died after 9 days from the onset of seizure, and a necropsy was performed. Histopathologically, the brain lesions in the meninges and the cerebral cortex of this dog was presented. There was severe diffuse nonsuppurative inflammation in perivascular area of the meninges and the cerebral white matter. Based on the results, this case was diagnosed as necrotizing meningoencephalitis in Maltese dog.

Keywords

References

  1. Bradley GA. Myocardial necrosis in a pug dog with necrotizing meningoencephalitis. Vet Pathol 1991; 28: 91-93 https://doi.org/10.1177/030098589102800116
  2. Cantile C, Chianini F, Arispici M, Fatzer R. Necrotizing meningoencephalitis association with cortical hippocampal hamartia in a pekingese dog. Vet Pathol 2001; 38: 119-122 https://doi.org/10.1354/vp.38-1-119
  3. Cordy DR, Holliday TA. Necrotizing meningoencephalitis of pug dogs. Vet Pathol 1989; 26: 191-194 https://doi.org/10.1177/030098588902600301
  4. Ducote JM, Johnson KE, Dewey CW, Walker MA, Coates JR, Berridge BR. Computed tomography of necrotizing meningoencephalitis in 3 yorkshire terriers. Vet Radiol Ultrasound 1999; 40: 617-621 https://doi.org/10.1111/j.1740-8261.1999.tb00888.x
  5. Fearnside SM, Kessell AE, Powe JR. Cervical hyperatesthesia in a maltese terrier with necrotising meningoencephalitis. Aust Vet J 2004; 82: 550-552 https://doi.org/10.1111/j.1751-0813.2004.tb11198.x
  6. Jull BA, Merryman JI, Thomas WB, McArthur A. Necrotizing meningoencephalitis in a yorkshire terrier. J Am Vet Med Assoc 1997; 211: 1005-1007
  7. Kobayashi Y, Ochiai K, Umemura T, Goto N, Ishida T, Itakura C. Necrotizing meningoencephalitis in pug dog in Japan. J Comp Pathol 1994; 110: 129-136 https://doi.org/10.1016/S0021-9975(08)80184-3
  8. Lotti D, Capucchio MT, Gaidolfi E, Merlo M. Necrotizing encephalitis in a yorkshire terrier: clinical imaging, and pathologic findings. Vet Radiol Ultrasound 1999; 40: 622-626 https://doi.org/10.1111/j.1740-8261.1999.tb00889.x
  9. Matsuki N, Fujiwara K, Tamahara S, Uchida K, Matsunaga S, Nakayama H, Doi K, Ogawa H, Ono K. Prevalence of autoboby in cerebrospinal fluids from dogs with various CNS Disease. J Vet Med Sci 2004; 66: 295-297 https://doi.org/10.1292/jvms.66.295
  10. Michael P. Nervous system. In: Saunders manual of small animal practice, 2nd ed. Philadelphia: WB Saunders. 2000: 1233-1310
  11. Sawashima Y, Sawashima K, Taura Y, Shimada A, Umemura T. Clinical and pathological finding of a yorkshire terrier affected with necrotizing encephalitis. J Vet Med Sci 1996; 58: 659-661 https://doi.org/10.1292/jvms.58.659
  12. Stalis IH, Chadwick B, Dayrell-Hart B, Summers BA, Van Winkle TJ. Necrotizing meningoencephalitis of maltese dogs. Vet Pathol 1995; 32: 230-235 https://doi.org/10.1177/030098589503200303
  13. Suzuki M, Uchida K, Morozumi M, Hasegawa T, Yanai T, Nakayama H, Tateyama S. A comparative pathological study on canine necrotizing meningoencephalitis and granulomatous meningoencephalitis. J Vet Med Sci 2003; 65: 1233-1239 https://doi.org/10.1292/jvms.65.1233
  14. Uchida K, Hasegawa T, Ikeda M, Yamaguchi R, Tateyama S. Detection of an autoantibody from pug dogs with necrotizing encephalitis (pug dog encephalitis). Vet Pathol 1999; 36: 301-307 https://doi.org/10.1354/vp.36-4-301
  15. 박은정, 김대용, 김재훈, 권오경. 퍼그견에서 발생한 괴사성 뇌막뇌염 증례보고. 한국임상수의학회지 1996; 36: 441-445