Journal of Microbiology and Biotechnology

The Korean Society for Microbiology and Biotechnology (한국미생물·생명공학회)
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Terrein, a Melanin Biosynthesis Inhibitor, from Penicillium sp. 20135

  • KIM WON-GON (Korea Research Institute of Bioscience and Biotechnology) ;
  • RYOO IN-JA (Korea Research Institute of Bioscience and Biotechnology) ;
  • PARK SEO-HYOUNG (Department of Dermatology, Seoul National University College of Medicine) ;
  • KIM DONG-SEOK (Department of Dermatology, Seoul National University College of Medicine) ;
  • LEE SANGKU (Korea Research Institute of Bioscience and Biotechnology) ;
  • PARK KYOUNG-CHAN (Department of Dermatology, Seoul National University College of Medicine) ;
  • YOO ICK-DONG (Korea Research Institute of Bioscience and Biotechnology)
  • Published : 2005.08.01
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Abstract

In the course of screening a melanin biosynthesis inhibitor, terrein, 4,5-dihydroxy-3-propenyl-2-cyclopenten-l-one, was isolated from Penicillium sp. Terrein was found to have a strong inhibitory activity on melanin formation in B 16 melanoma and melanocyte Mel-Ab cells.

Keywords

References

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