Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
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A Case of Idiopathic Hypereosinophilic Syndrome Complicated with Pulmonary Thromboembolism and Disseminated Intravascular Coagulation

폐색전증과 파종성혈관내응고가 합병된 특발성 과호산구 증후군 1례

  • Lee, Jong Sung (Department of Internal Medicine, Seoul Paik Hospital, Inje University) ;
  • Lee, Hyun-Kyung (Department of Internal Medicine, Seoul Paik Hospital, Inje University) ;
  • Lee, Sung Soon (Department of Internal Medicine, Seoul Paik Hospital, Inje University) ;
  • Jin, Jae Yong (Department of Internal Medicine, Seoul Paik Hospital, Inje University) ;
  • Lee, Young Min (Department of Internal Medicine, Seoul Paik Hospital, Inje University) ;
  • Lee, Hyuk Pyo (Department of Internal Medicine, Seoul Paik Hospital, Inje University) ;
  • Kim, Joo In (Department of Internal Medicine, Seoul Paik Hospital, Inje University) ;
  • Ku, Bon Il (Department of Thoracic Surgery, Seoul Paik Hospital, Inje University) ;
  • Choi, Soo Jeon (Department of Internal Medicine, Seoul Paik Hospital, Inje University) ;
  • Yum, Ho-Kee (Department of Internal Medicine, Seoul Paik Hospital, Inje University)
  • 이종성 (인제대학교 서울백병원 내과학교실) ;
  • 이현경 (인제대학교 서울백병원 내과학교실) ;
  • 이성순 (인제대학교 서울백병원 내과학교실) ;
  • 진재용 (인제대학교 서울백병원 내과학교실) ;
  • 이영민 (인제대학교 서울백병원 내과학교실) ;
  • 이혁표 (인제대학교 서울백병원 내과학교실) ;
  • 김주인 (인제대학교 서울백병원 내과학교실) ;
  • 구본일 ;
  • 최수전 (인제대학교 서울백병원 내과학교실) ;
  • 염호기 (인제대학교 서울백병원 내과학교실)
  • Received : 2004.06.14
  • Accepted : 2004.08.25
  • Published : 2004.12.30
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Abstract

The idiopathic hypereosinophilic syndrome (HES) comprises a heterogeneous group of disorders with unknown pathogenesis characterized by persistent peripheral blood and bone marrow eosinophilia. And the eosinophil infiltrates of multiple organs in HES lead to severe organ dysfunction. The disseminated intravascular coagulation (DIC) is a rare complication of HES. We have experienced a case of HES complicated with DIC and pulmonary thromboembolism. After intravenous injection of methylprednisone, blood eosinophil count was normalized but DIC was persisted. With cortico steroid and cyclosporine therapy, the disease activity was favorably remitted.

저자들은 폐색전증과 파종성혈관내응고를 동반한 특발성 과호산구 증후군 1례를 경험하였다. 환자는 스테로이드 투여로 빠른 호전이 없어 시클로스포린을 추가하여 호전되었다.

Keywords

References

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